Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 3 Interventional

Evaluation of CureXcell® in Treating Lower Extremity Chronic Ulcers in Adults With Diabetes

ClinicalTrials.gov ID: NCT01421966

Public ClinicalTrials.gov record NCT01421966. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 9, 2026, 8:52 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Multicenter, Randomized, Double-Blind, Parallel-Group, Sham-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of CureXcell® as an Adjunct to Good Wound Care in Lower Extremity Chronic Ulcers in Adults With Diabetes Mellitus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Chronic foot ulcers are particularly prevalent in patients with underlying diabetes mellitus. These ulcers are reported to be the leading cause of hospitalization among people with diabetes. The purpose of this study is to evaluate CureXcell® in treating chronic lower extremity ulcers in adults with diabetes mellitus. CureXcell® is a cell based therapy, containing activated homologous white blood cells prepared from donated healthy whole blood. A total of 280 patients will be randomized to receive either CureXcell® or sham.

Study identification

NCT ID
NCT01421966
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Macrocure Ltd.
Industry
Enrollment
285 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2011
Primary completion
Jan 31, 2015
Completion
Sep 30, 2015
Last update posted
Dec 6, 2015

2011 – 2015

United States locations

U.S. sites
31
U.S. states
16
U.S. cities
31
Facility City State ZIP Site status
Not listed Glendale Arizona
Not listed Mesa Arizona
Not listed Phoenix Arizona
Not listed Tucson Arizona
Not listed Fresno California
Not listed San Francisco California
Not listed Sylmar California
Not listed Gulf Breeze Florida
Not listed Hialeah Florida
Not listed Miami Florida
Not listed South Miami Florida
Not listed Evans Georgia
Not listed Arlington Heights Illinois
Not listed Chicago Illinois
Not listed Oak Park Illinois
Not listed Indianapolis Indiana
Not listed Wichita Kansas
Not listed Boston Massachusetts
Not listed Kansas City Missouri
Not listed Toms River New Jersey
Not listed Mineola New York
Not listed New York New York
Not listed Lima Ohio
Not listed Aiken South Carolina
Not listed Greenville South Carolina
Not listed Dallas Texas
Not listed Lewisville Texas
Not listed McAllen Texas
Not listed San Antonio Texas
Not listed Salt Lake City Utah
Not listed Norfolk Virginia

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01421966, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 6, 2015 · Synced Sep 9, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01421966 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →