Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder
Public ClinicalTrials.gov record NCT01428661. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
MAGELLAN: A Multicenter, Randomized, Double-Masked, Placebo-Controlled, Parallel Study to Investigate the Safety and Efficacy of 20 Mg Tasimelteon Versus Placebo in Adult Subjects With Major Depressive Disorder Followed by a 52-Week Open-Label Extension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and efficacy of an 8-week double-masked treatment of tasimelteon or placebo in male and female subjects with Major Depressive Disorder.
Study identification
- NCT ID
- NCT01428661
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 507 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2011 (Type not available)
- Primary completion
- Jan 2013 (Actual)
- Completion
- May 2013 (Actual)
- Last update posted
- Jun 19, 2015
2011 – 2013
United States locations
- U.S. sites
- 40
- U.S. states
- 20
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Vanda Investigational Site | Garden Grove | California | 92845 | — |
| Vanda Investigational Site | Irvine | California | 92617 | — |
| Vanda Investigational Site | Los Alamitos | California | 90720 | — |
| Vanda Investigational Site | Oakland | California | 94612 | — |
| Vanda Investigational Site | Oceanside | California | 92056 | — |
| Vanda Investigational Site | San Diego | California | 92102 | — |
| Vanda Investigational Site | Sherman Oaks | California | 91403 | — |
| Vanda Investigational Site | Torrance | California | 90502 | — |
| Vanda Investigational Site | Denver | Colorado | 80239 | — |
| Vanda Investigational Site | Bradenton | Florida | 34201 | — |
| Vanda Investigational Site | Jacksonville | Florida | 32216 | — |
| Vanda Investigational Site | Maitland | Florida | 32751 | — |
| Vanda Investigational Site | North Miami | Florida | 33161 | — |
| Vanda Investigational Site | Orlando | Florida | 32806 | — |
| Vanda Investigational Site | Atlanta | Georgia | 30308 | — |
| Vanda Investigational Site | Atlanta | Georgia | 30328 | — |
| Vanda Investigational Site | Chicago | Illinois | 60640 | — |
| Vanda Investigational Site | Joliet | Illinois | 60435 | — |
| Vanda Investigational Site | Prairie Village | Kansas | 66205 | — |
| Vanda Investigational Site | Baltimore | Maryland | 21208 | — |
| Vanda Investigational Site | Boston | Massachusetts | 02135 | — |
| Vanda Investigational Site | Omaha | Nebraska | 68198 | — |
| Vanda Investigational Site | Las Vegas | Nevada | 89102 | — |
| Vanda Investigational Site | Toms River | New Jersey | 08755 | — |
| Vanda Investigational Site | Willingboro | New Jersey | 08046 | — |
| Vanda Investigational Site | Brooklyn | New York | 11235 | — |
| Vanda Investigational Site | Mount Kisco | New York | 10549 | — |
| Vanda Investigational Site | New York | New York | 10168 | — |
| Vanda Investigational Site | Rochester | New York | 14618 | — |
| Vanda Investigational Site | Staten Island | New York | 10312 | — |
| Vanda Investigational Site | Cincinnati | Ohio | 45267 | — |
| Vanda Investigational Site | Dayton | Ohio | 45417 | — |
| Vanda Investigational Site | Portland | Oregon | 97210 | — |
| Vanda Investigational Site | Lincoln | Rhode Island | 02865 | — |
| Vanda Investigational Site | Memphis | Tennessee | 38119 | — |
| Vanda Investigational Site | Austin | Texas | 78731 | — |
| Vanda Investigational Site | Dallas | Texas | 75231 | — |
| Vanda Investigational Site | Salt Lake City | Utah | 84106 | — |
| Vanda Investigational Site | Seattle | Washington | 98104 | — |
| Vanda Investigational Site | Brown Deer | Wisconsin | 53223 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01428661, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 19, 2015 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01428661 live on ClinicalTrials.gov.