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Completed Phase 2Phase 3 Interventional Results available

Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder

ClinicalTrials.gov ID: NCT01428661

Public ClinicalTrials.gov record NCT01428661. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 6:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

MAGELLAN: A Multicenter, Randomized, Double-Masked, Placebo-Controlled, Parallel Study to Investigate the Safety and Efficacy of 20 Mg Tasimelteon Versus Placebo in Adult Subjects With Major Depressive Disorder Followed by a 52-Week Open-Label Extension

Study identification

NCT ID
NCT01428661
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Vanda Pharmaceuticals
Industry
Enrollment
507 participants

Conditions and interventions

Interventions

  • placebo Drug
  • tasimelteon Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2011
Primary completion
Dec 31, 2012
Completion
Apr 30, 2013
Last update posted
Jun 18, 2015

2011 – 2013

United States locations

U.S. sites
40
U.S. states
20
U.S. cities
39
Facility City State ZIP Site status
Vanda Investigational Site Garden Grove California 92845
Vanda Investigational Site Irvine California 92617
Vanda Investigational Site Los Alamitos California 90720
Vanda Investigational Site Oakland California 94612
Vanda Investigational Site Oceanside California 92056
Vanda Investigational Site San Diego California 92102
Vanda Investigational Site Sherman Oaks California 91403
Vanda Investigational Site Torrance California 90502
Vanda Investigational Site Denver Colorado 80239
Vanda Investigational Site Bradenton Florida 34201
Vanda Investigational Site Jacksonville Florida 32216
Vanda Investigational Site Maitland Florida 32751
Vanda Investigational Site North Miami Florida 33161
Vanda Investigational Site Orlando Florida 32806
Vanda Investigational Site Atlanta Georgia 30308
Vanda Investigational Site Atlanta Georgia 30328
Vanda Investigational Site Chicago Illinois 60640
Vanda Investigational Site Joliet Illinois 60435
Vanda Investigational Site Prairie Village Kansas 66205
Vanda Investigational Site Baltimore Maryland 21208
Vanda Investigational Site Boston Massachusetts 02135
Vanda Investigational Site Omaha Nebraska 68198
Vanda Investigational Site Las Vegas Nevada 89102
Vanda Investigational Site Toms River New Jersey 08755
Vanda Investigational Site Willingboro New Jersey 08046
Vanda Investigational Site Brooklyn New York 11235
Vanda Investigational Site Mount Kisco New York 10549
Vanda Investigational Site New York New York 10168
Vanda Investigational Site Rochester New York 14618
Vanda Investigational Site Staten Island New York 10312
Vanda Investigational Site Cincinnati Ohio 45267
Vanda Investigational Site Dayton Ohio 45417
Vanda Investigational Site Portland Oregon 97210
Vanda Investigational Site Lincoln Rhode Island 02865
Vanda Investigational Site Memphis Tennessee 38119
Vanda Investigational Site Austin Texas 78731
Vanda Investigational Site Dallas Texas 75231
Vanda Investigational Site Salt Lake City Utah 84106
Vanda Investigational Site Seattle Washington 98104
Vanda Investigational Site Brown Deer Wisconsin 53223

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01428661, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 18, 2015 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01428661 live on ClinicalTrials.gov.

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