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Completed Phase 2 Interventional

Dose Finding Study for QAW039 in Asthma

ClinicalTrials.gov ID: NCT01437735

Public ClinicalTrials.gov record NCT01437735. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 11:55 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Placebo-controlled, Dose-ranging, Multi-centre Trial of QAW039 (1-450 mg p.o.), to Investigate the Effect on FEV1 and ACQ in Patients With Moderate-to-severe, Persistent, Allergic Asthma, Inadequately Controlled With ICS Therapy.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study aims to demonstrate a clinically significant improvement in Forced Expiratory Volume in one second (FEV1) in moderate to severe allergic asthmatics inadequately controlled by Inhaled Corticosteroid (ICS) therapy. Patients will be treated with QAW039, an active comparator, or placebo. This will be a randomized, placebo-controlled, dose-ranging, multi-centre trial.

Study identification

NCT ID
NCT01437735
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
1,043 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2011
Primary completion
Oct 31, 2013
Completion
Oct 31, 2013
Last update posted
Dec 18, 2020

2011 – 2013

United States locations

U.S. sites
38
U.S. states
21
U.S. cities
36
Facility City State ZIP Site status
Novartis Investigative Site Scottsdale Arizona 85251
Novartis Investigative Site Encinitas California 92024
Novartis Investigative Site Huntington Beach California 92647
Novartis Investigative Site Los Angeles California 90048
Novartis Investigative Site Orange California 92868
Novartis Investigative Site Riverside California 92506
Novartis Investigative Site San Diego California 92120
Novartis Investigative Site San Diego California 92123
Novartis Investigative Site San Jose California 95117
Novartis Investigative Site San Mateo California 94401
Novartis Investigative Site Stockton California 95207
Novartis Investigative Site Centennial Colorado 80112
Novartis Investigative Site Denver Colorado 80230
Novartis Investigative Site Sarasota Florida 34233
Novartis Investigative Site Savannah Georgia 31406
Novartis Investigative Site River Forest Illinois 60305
Novartis Investigative Site Bangor Maine 04401
Novartis Investigative Site Wheaton Maryland 20902
Novartis Investigative Site North Dartmouth Massachusetts 02747
Novartis Investigative Site Minneapolis Minnesota 55402
Novartis Investigative Site St Louis Missouri 63141
Novartis Investigative Site Warrensburg Missouri 64093
Novartis Investigative Site Omaha Nebraska 68130
Novartis Investigative Site Omaha Nebraska 68131
Novartis Investigative Site Papillion Nebraska 68046
Novartis Investigative Site Skillman New Jersey 08558
Novartis Investigative Site Canton Ohio 44718
Novartis Investigative Site Columbus Ohio 43213
Novartis Investigative Site Oklahoma City Oklahoma 73103
Novartis Investigative Site Lake Oswego Oregon 97035
Novartis Investigative Site Medford Oregon 97504-8741
Novartis Investigative Site Erie Pennsylvania 16507
Novartis Investigative Site Lincoln Rhode Island 02865
Novartis Investigative Site Charleston South Carolina 29407
Novartis Investigative Site Dallas Texas 75231
Novartis Investigative Site Fort Worth Texas 76132
Novartis Investigative Site Waco Texas 76712
Novartis Investigative Site South Burlington Vermont 05403

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 168 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01437735, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 18, 2020 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01437735 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →