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Completed Phase 2 Interventional Results available

A Study of the Efficacy and Safety of MEDI-546 in Systemic Lupus Erythematosus

ClinicalTrials.gov ID: NCT01438489

Public ClinicalTrials.gov record NCT01438489. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 4, 2026, 4:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized Study to Evaluate the Efficacy and Safety of MEDI-546 in Subjects With Systemic Lupus Erythematosus

Study identification

NCT ID
NCT01438489
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
MedImmune LLC
Industry
Enrollment
626 participants

Conditions and interventions

Interventions

  • Anifrolumab 1000 mg Biological
  • Anifrolumab 300 mg Biological
  • Placebo Other

Biological · Other

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2011
Primary completion
Mar 31, 2015
Completion
Mar 31, 2015
Last update posted
Oct 6, 2016

2012 – 2015

United States locations

U.S. sites
30
U.S. states
15
U.S. cities
30
Facility City State ZIP Site status
Research Site Birmingham Alabama
Research Site La Jolla California
Research Site La Palma California
Research Site Long Beach California
Research Site Los Angeles California
Research Site Palm Desert California
Research Site San Leandro California
Research Site Upland California
Research Site Miami Florida
Research Site Ocala Florida
Research Site Orlando Florida
Research Site Palm Harbor Florida
Research Site Tampa Florida
Research Site Atlanta Georgia
Research Site Decatur Georgia
Research Site Stockbridge Georgia
Research Site Idaho Falls Idaho
Research Site Chicago Illinois
Research Site Indianapolis Indiana
Research Site Las Cruces New Mexico
Research Site New York New York
Research Site Charlotte North Carolina
Research Site Raleigh North Carolina
Research Site Columbus Ohio
Research Site Edmond Oklahoma
Research Site Tulsa Oklahoma
Research Site Memphis Tennessee
Research Site Houston Texas
Research Site Seattle Washington
Research Site Spokane Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 49 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01438489, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 6, 2016 · Synced May 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01438489 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →