Open Label Study of Long Term Evaluation Against LDL-C Trial
Public ClinicalTrials.gov record NCT01439880. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Controlled, Open-label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of AMG 145 (Evolocumab)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary clinical hypothesis is that long-term exposure of evolocumab (AMG 145) will be safe and well tolerated in adults with hypercholesterolemia.
Study identification
- NCT ID
- NCT01439880
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 1,324 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 7, 2011 (Actual)
- Primary completion
- Jun 20, 2018 (Actual)
- Completion
- Jun 20, 2018 (Actual)
- Last update posted
- Sep 21, 2022
2011 – 2018
United States locations
- U.S. sites
- 78
- U.S. states
- 31
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35216 | — |
| Research Site | Birmingham | Alabama | 35294 | — |
| Research Site | Tucson | Arizona | 85710 | — |
| Research Site | Little Rock | Arkansas | 72205 | — |
| Research Site | Malvern | Arkansas | 72104 | — |
| Research Site | Anaheim | California | 92801 | — |
| Research Site | Carmichael | California | 95608 | — |
| Research Site | Inglewood | California | 90301 | — |
| Research Site | Mission Viejo | California | 92691 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Thousand Oaks | California | 91360 | — |
| Research Site | Tustin | California | 92780 | — |
| Research Site | Colorado Springs | Colorado | 80909 | — |
| Research Site | Littleton | Colorado | 80120 | — |
| Research Site | Daytona Beach | Florida | 32117 | — |
| Research Site | DeLand | Florida | 32720 | — |
| Research Site | Green Cove Springs | Florida | 32043 | — |
| Research Site | Jacksonville | Florida | 32216 | — |
| Research Site | Jacksonville | Florida | 32223 | — |
| Research Site | Melbourne | Florida | 32901 | — |
| Research Site | Miami | Florida | 33144 | — |
| Research Site | Miami | Florida | 33173 | — |
| Research Site | Ponte Vedra | Florida | 32081 | — |
| Research Site | Port Charlotte | Florida | 33952 | — |
| Research Site | Sanford | Florida | 32771 | — |
| Research Site | Atlanta | Georgia | 30338 | — |
| Research Site | Savannah | Georgia | 31406 | — |
| Research Site | Chicago | Illinois | 60654 | — |
| Research Site | Indianapolis | Indiana | 46260 | — |
| Research Site | Munster | Indiana | 46321 | — |
| Research Site | Iowa City | Iowa | 52242 | — |
| Research Site | Louisville | Kentucky | 40213 | — |
| Research Site | Auburn | Maine | 04210 | — |
| Research Site | Portland | Maine | 04101 | — |
| Research Site | Bethesda | Maryland | 20817 | — |
| Research Site | Chevy Chase | Maryland | 20815 | — |
| Research Site | Brockton | Massachusetts | 02301 | — |
| Research Site | Marquette | Michigan | 49855 | — |
| Research Site | Brooklyn Center | Minnesota | 55430 | — |
| Research Site | Tupelo | Mississippi | 38801 | — |
| Research Site | Great Falls | Montana | 59405 | — |
| Research Site | Henderson | Nevada | 89052 | — |
| Research Site | Las Vegas | Nevada | 89117 | — |
| Research Site | Las Vegas | Nevada | 89148 | — |
| Research Site | Cortlandt Manor | New York | 10567 | — |
| Research Site | Endwell | New York | 13760 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | Williamsville | New York | 14221 | — |
| Research Site | Raleigh | North Carolina | 27609 | — |
| Research Site | Raleigh | North Carolina | 27612 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Fargo | North Dakota | 58103 | — |
| Research Site | Akron | Ohio | 44311 | — |
| Research Site | Cadiz | Ohio | 43907 | — |
| Research Site | Cincinnati | Ohio | 45219 | — |
| Research Site | Cincinnati | Ohio | 45227 | — |
| Research Site | Cincinnati | Ohio | 45246 | — |
| Research Site | Cleveland | Ohio | 44122 | — |
| Research Site | Dayton | Ohio | 45414 | — |
| Research Site | Norman | Oklahoma | 73069 | — |
| Research Site | Oklahoma City | Oklahoma | 73103 | — |
| Research Site | Camp Hill | Pennsylvania | 17011 | — |
| Research Site | Duncansville | Pennsylvania | 16635 | — |
| Research Site | Pittsburgh | Pennsylvania | 15216 | — |
| Research Site | York | Pennsylvania | 17405 | — |
| Research Site | Mt. Pleasant | South Carolina | 29464 | — |
| Research Site | Rapid City | South Dakota | 57701 | — |
| Research Site | Rapid City | South Dakota | 57702 | — |
| Research Site | Bristol | Tennessee | 37620 | — |
| Research Site | Arlington | Texas | 76018 | — |
| Research Site | Houston | Texas | 77002 | — |
| Research Site | Houston | Texas | 77074 | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | Norfolk | Virginia | 23502 | — |
| Research Site | Richmond | Virginia | 23294 | — |
| Research Site | Renton | Washington | 98057 | — |
| Research Site | Seattle | Washington | 98122 | — |
| Research Site | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 109 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01439880, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2022 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01439880 live on ClinicalTrials.gov.