A Trial of TH-302 in Combination With Doxorubicin Versus Doxorubicin Alone to Treat Patients With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Public ClinicalTrials.gov record NCT01440088. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase 3, Multicenter, Open-Label Study Comparing TH-302 in Combination With Doxorubicin vs. Doxorubicin Alone in Subjects With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether TH-302 in combination with Doxorubicin is safe and effective in the treatment of Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma.
Study identification
- NCT ID
- NCT01440088
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 640 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 15 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2011 (Type not available)
- Primary completion
- Dec 2015 (Actual)
- Completion
- May 2016 (Actual)
- Last update posted
- Jun 2, 2016
2011 – 2016
United States locations
- U.S. sites
- 44
- U.S. states
- 25
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Arizona | Scottsdale | Arizona | 85259 | — |
| Arizona Cancer Center | Tucson | Arizona | 85719 | — |
| USC-Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| University of California, Los Angeles | Los Angeles | California | 90095-6901 | — |
| Sarcoma Oncology Center | Santa Monica | California | 90403 | — |
| Stanford Comprehensive Cancer Center | Stanford | California | 94305 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Washington Cancer Institute | Washington D.C. | District of Columbia | 20010 | — |
| South Florida Center for Gynecologic Oncology | Boca Raton | Florida | 33487 | — |
| Mayo Clinic-Florida-Cancer Clinical Studies Unit | Jacksonville | Florida | 32224 | — |
| MD Anderson Cancer Center Orlando | Orlando | Florida | 32806 | — |
| H.Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | — |
| Winship Cancer Institute of Emory University, Midtown Campus | Atlanta | Georgia | 30322 | — |
| Kootenai Health - Kootenai Cancer Center | Coeur d'Alene | Idaho | 83814 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Oncology Specialists | Park Ridge | Illinois | 60068 | — |
| Indiana University Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| University of Iowa Health Care - University of Iowa Hospital | Iowa City | Iowa | 52242 | — |
| Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Dana Farber Cancer Institute Center for Sarcoma and Bone Oncology | Boston | Massachusetts | 02215 | — |
| University of Michigan Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Mayo Rochester | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10031 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Montefiore | The Bronx | New York | 10461 | — |
| Carolinas Hematology-oncology Associates-Blumenthal Cancer Center | Charlotte | North Carolina | 28203 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| University Hospitals Seidman Cancer Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| The Arthur G. James Cancer Hospital and Richard J Solove Research Institue, The Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43202 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Pennsylvania Oncology Hematology Associates | Philadelphia | Pennsylvania | 19106 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| University of Pittsburg Medical Center | Pittsburgh | Pennsylvania | 15232 | — |
| MUSC - Hollings Cancer Center | Charleston | South Carolina | 29425 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| University of Vermont | Burlington | Vermont | 05405 | — |
| Virginia Commonwealth Universtiy-Massey Cancer Center | Richmond | Virginia | 23298 | — |
| University of Washington Cancer Center | Seattle | Washington | 98109 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01440088, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 2, 2016 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01440088 live on ClinicalTrials.gov.