Autopsy Follow-up of Subjects Previously Imaged With Florbetapir F 18 (18F-AV-45) PET in Trial 18F-AV-45-A07
Public ClinicalTrials.gov record NCT01447719. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to test the relationship between measurements of brain amyloid using florbetapir F 18 PET imaging and true levels of amyloid plaque density as measured by histopathological assessment. The study will address the following specific aims: 1. To expand the number of subjects included in the A07 (NCT00857415) trial correlation analysis (measuring the correlation between the global visual rating of brain amyloid plaque density on an independent blinded read of the florbetapir F 18 PET scan and the cortical amyloid plaque density at autopsy as assessed by histopathology for subjects in the autopsy cohort). 2. To determine the sensitivity and specificity of an independent blinded visual read assessment of the florbetapir F 18 PET scan (Aβ+ or Aβ-) versus the final blinded neuropathological assessment made at autopsy.
Study identification
- NCT ID
- NCT01447719
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 110 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2010
- Primary completion
- Feb 28, 2011
- Completion
- Jun 30, 2011
- Last update posted
- Mar 20, 2025
2010 – 2011
United States locations
- U.S. sites
- 22
- U.S. states
- 13
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Phoenix | Arizona | 85006 | — |
| Research Site | Sun City | Arizona | 85351 | — |
| Research Site | Little Rock | Arkansas | 72211 | — |
| Research Site | Irvine | California | 92697 | — |
| Research Site | Fort Myers | Florida | 33912 | — |
| Research Site | Miami | Florida | 33137 | — |
| Research Site | Miami Beach | Florida | 33140 | — |
| Research Site | Miami Springs | Florida | 33166 | — |
| Research Site | Orlando | Florida | 32835 | — |
| Research Site | Sarasota | Florida | 34231 | — |
| Research Site | St. Petersburg | Florida | 33709 | — |
| Research Site | West Palm Beach | Florida | 33407 | — |
| Research Site | Baltimore | Maryland | 21221 | — |
| Research Site | Hattiesburg | Mississippi | 39401 | — |
| Research Site | St Louis | Missouri | 63141 | — |
| Research Site | Albany | New York | 12208 | — |
| Research Site | New Hyde Park | New York | 11040 | — |
| Research Site | Durham | North Carolina | 27710 | — |
| Research Site | Centerville | Ohio | 45459 | — |
| Research Site | Oklahoma City | Oklahoma | 73112 | — |
| Research Site | Charleston | South Carolina | 29425 | — |
| Research Site | Johnson City | Tennessee | 37614 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01447719, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 20, 2025 · Synced Sep 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01447719 live on ClinicalTrials.gov.