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Terminated Phase 3 Interventional

Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE)

ClinicalTrials.gov ID: NCT01449292

Public ClinicalTrials.gov record NCT01449292. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 12:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to demonstrate the safety and efficacy of AeriSeal System treatment plus optimal medical therapy compared in patients with advanced upper lobe predominant (ULP) heterogeneous emphysema.

Study identification

NCT ID
NCT01449292
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Aeris Therapeutics
Industry
Enrollment
300 participants

Conditions and interventions

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2012 (Type not available)
Primary completion
Nov 2013 (Actual)
Completion
Nov 2013 (Actual)
Last update posted
Nov 14, 2013

2012 – 2013

United States locations

U.S. sites
29
U.S. states
22
U.S. cities
28
Facility City State ZIP Site status
The University of Alabama at Birmingham Birmingham Alabama 35249 —
Pulmonary Associates Phoenix Arizona 85006 —
David Geffen School of Medicine at UCLA Los Angeles California 90095 —
Yale-New Haven Hospital New Haven Connecticut 06510 —
Miami VA Healthcare System (accepting Miami VA patients only) Miami Florida 33136 —
Emory University Hospital Atlanta Georgia 30308 —
The University of Chicago Medicine Chicago Illinois 60637 —
Presence Saint Joseph Medical Center Joliet Illinois 60435 —
Illinois Lung Institute Peoria Illinois 61606 —
University of Iowa Hospitals and Clinics Iowa City Iowa 55242 —
Veritas Clinical Specialties, Ltd. Topeka Kansas 66606 —
The Johns Hopkins Hospital Baltimore Maryland 21287 —
Brigham and Women's Hospital Boston Massachusetts 02115 —
St. Elizabeth's Medical Center Boston Massachusetts 02135 —
Lahey Clinic Burlington Massachusetts 01805 —
Mayo Clinic Rochester Minnesota 55905 —
Washington University St Louis Missouri 63110 —
Jamaica Hospital Medical Center Jamaica New York 11418 —
South Nassau Communities Hospital Oceanside New York 11572 —
Duke University Medical Center Durham North Carolina 27710 —
FirstHealth Moore Regional Hospital Pinehurst North Carolina 28374 —
Wake Forest Baptist Medical Center Winston-Salem North Carolina 27157 —
Cleveland Clinic Cleveland Ohio 44195 —
Kaiser Foundation Hospitals (accepting Kaiser patients only) Portland Oregon 97227 —
Temple University Hospital Philadelphia Pennsylvania 19140 —
University of South Carolina School of Medicine Columbia South Carolina 29203 —
UT Southwestern Medical Center Dallas Texas 75390 —
University of Utah Salt Lake City Utah 84112 —
Carilion Roanoke Memorial Hospital Roanoke Virginia 24014 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01449292, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 14, 2013 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01449292 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →