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Completed Phase 3 Interventional

A Study of Onartuzumab (MetMAb) in Combination With Tarceva (Erlotinib) in Participants With Met Diagnostic-Positive Non-Small Cell Lung Cancer Who Have Received Chemotherapy For Advanced or Metastatic Disease (MetLung)

ClinicalTrials.gov ID: NCT01456325

Public ClinicalTrials.gov record NCT01456325. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 11:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Phase III, Multicenter, Double-Blind, Placebo-Controlled Study Evaluating Efficacy and Safety of Onartuzumab (Metmab) in Combination With Tarceva (Erlotinib) in Patients With Met Diagnostic-Positive Non-Small Cell Lung Cancer Who Have Received Standard Chemotherapy for Advanced/Metastatic Disease

Study identification

NCT ID
NCT01456325
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Genentech, Inc.
Industry
Enrollment
494 participants

Conditions and interventions

Interventions

  • Erlotinib Drug
  • Onartuzumab (MetMab) Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2011
Primary completion
Dec 31, 2015
Completion
Dec 31, 2015
Last update posted
Nov 1, 2016

2012 – 2016

United States locations

U.S. sites
56
U.S. states
22
U.S. cities
50
Facility City State ZIP Site status
Not listed Chandler Arizona 85224
Not listed Hayward California 94545
Not listed Modesto California 95355
Not listed Oakland California 94611
Not listed Orange California 92868
Not listed Roseville California 95661
Not listed Sacramento California 95817
Not listed Sacramento California 95825
Not listed San Diego California 92108
Not listed San Francisco California 94115
Not listed San Jose California 95119
Not listed Santa Clara California 95051
Not listed South San Francisco California 94080
Not listed Vallejo California 94589
Not listed Walnut Creek California 94596
Not listed Boca Raton Florida 33486
Not listed Clearwater Florida 33761
Not listed Fort Myers Florida 33901
Not listed Jacksonville Florida 32207
Not listed Jacksonville Florida 32256
Not listed Chicago Illinois 60637
Not listed Urbana Illinois 61801
Not listed Bettendorf Iowa 52722
Not listed Sioux City Iowa 51101
Not listed Louisville Kentucky 40207
Not listed Annapolis Maryland 21401
Not listed Baltimore Maryland 21201
Not listed Baltimore Maryland 21231
Not listed Baltimore Maryland 21237
Not listed Boston Massachusetts 02114
Not listed Boston Massachusetts 02115
Not listed Springfield Massachusetts 01107
Not listed Ann Arbor Michigan 48106
Not listed Duluth Minnesota 55805
Not listed St Louis Missouri 63110
Not listed Omaha Nebraska 68114
Not listed Reno Nevada 89502
Not listed Farmington New Mexico 87401
Not listed Syracuse New York 13210
Not listed Chapel Hill North Carolina 27514
Not listed Canton Ohio 44718
Not listed Cleveland Ohio 44106
Not listed Columbus Ohio 43210
Not listed Columbus Ohio 43219
Not listed Philadelphia Pennsylvania 19104
Not listed Pittsburgh Pennsylvania 15232
Not listed Charleston South Carolina 29403
Not listed Columbia South Carolina 29210
Not listed Chattanooga Tennessee 37404
Not listed Knoxville Tennessee 37909
Not listed Nashville Tennessee 37203
Not listed Dallas Texas 75390
Not listed Fort Worth Texas 76104
Not listed Houston Texas 77030
Not listed Bristol Virginia 24201
Not listed Roanoke Virginia 24014

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 157 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01456325, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 1, 2016 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01456325 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →