A Study To Evaluate Both The Efficacy and Safety Profile of CP-690,550 In Patients With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT01458951. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Randomized, Double-blind, Placebo-controlled, Parallel-group Study Of Oral Cp-690,550 As An Induction Therapy In Subjects With Moderate To Severe Ulcerative Colitis.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to evaluate the efficacy and safety of tofacitinib (CP-690,550) in patients with moderate to severe ulcerative colitis who have failed or be intolerant to one of following treatments for ulcerative colitis: oral steroids, azathiopurine/6-mercaptopurine, or anti-TNF-alpha therapy.
Study identification
- NCT ID
- NCT01458951
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 547 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2012 (Type not available)
- Primary completion
- May 2015 (Actual)
- Completion
- Jun 2015 (Actual)
- Last update posted
- Jun 1, 2016
2012 – 2015
United States locations
- U.S. sites
- 62
- U.S. states
- 19
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Desert Sun Clinical Research, LLC | Tucson | Arizona | 85710 | — |
| Desert Sun Gastroenterology | Tucson | Arizona | 85710 | — |
| Desert Sun Surgery Center | Tucson | Arizona | 85710 | — |
| Alliance Clinical Research | Oceanside | California | 92056 | — |
| Clinical Application Laboratories | San Diego | California | 92103 | — |
| San Diego Endoscopy Center | San Diego | California | 92103 | — |
| UCSF Endoscopy Unit at Mount Zion | San Francisco | California | 94115 | — |
| University of California San Francisco | San Francisco | California | 94115 | — |
| Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| Bristol Hospital | Bristol | Connecticut | 06010 | — |
| Connecticut Clinical Research Foundation | Bristol | Connecticut | 06010 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Central Connecticut Endoscopy Center | Plainville | Connecticut | 06062 | — |
| Citrus Surgery & Endoscopy Center (Colonoscopy) | Crystal River | Florida | 34429 | — |
| Nature Coast Clinical Research | Inverness | Florida | 34452 | — |
| Suncoast Endoscopy Center (colonoscopy) | Inverness | Florida | 34453 | — |
| Gastroenterology Group of Naples | Naples | Florida | 34102 | — |
| Advanced Gastroenterology Center | Port Orange | Florida | 32127 | — |
| Advanced Medical Research Center | Port Orange | Florida | 32127 | — |
| Endoscopy Center | Port Orange | Florida | 32127 | — |
| Port Orange Urgent Care | Port Orange | Florida | 32127 | — |
| Atlanta Center for Gastroenterology, P.C. | Decatur | Georgia | 30033 | — |
| Cotton-O'Neil Clinical Research Center, Digestive Health | Topeka | Kansas | 66606 | — |
| Gastrointestinal Specialists, A.M.C. | Shreveport | Louisiana | 71103 | — |
| Shreveport Endoscopy Center, A.M.C. | Shreveport | Louisiana | 71103 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Chevy Chase Endoscopy Center (Endoscopies Only) | Chevy Chase | Maryland | 20815 | — |
| MGG Group Co., Inc., Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | — |
| Clinical Research Institute of Michigan, LLC | Chesterfield | Michigan | 48047 | — |
| Center for Digestive Health | Troy | Michigan | 48098 | — |
| Surgical Centers of Michigan | Troy | Michigan | 48098 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Surgery Center of Columbia | Columbia | Missouri | 65201 | — |
| Hannibal Regional Hospital | Hannibal | Missouri | 63401 | — |
| Audrain Medical Center | Mexico | Missouri | 65265 | — |
| Center for Digestive & Liver Disease, Inc. | Mexico | Missouri | 65265 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| AGA Clinical Research Associates, LLC | Egg Harbor | New Jersey | 08234 | — |
| South Jersey Gastroenterology | Marlton | New Jersey | 08053 | — |
| The Gastroenterology Group of South Jersey | Vineland | New Jersey | 08360 | — |
| The Endo Center at Voorhees | Voorhees Township | New Jersey | 08043 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Carolina Research - Carolina Digestive Diseases | Greenville | North Carolina | 27834 | — |
| Regional Gastroenterology Associates of Lancaster, Ltd. | Lancaster | Pennsylvania | 17604 | — |
| Vanderbilt University Medical Center - IBD Clinic | Nashville | Tennessee | 37212-1375 | — |
| Vanderbilt University Medical Center - GI Research Office | Nashville | Tennessee | 37212-1610 | — |
| Vanderbilt University Medical Center - Drug Shipment | Nashville | Tennessee | 37232-7610 | — |
| Vanderbilt University Medical Center - GCRC | Nashville | Tennessee | 37232 | — |
| Vanderbilt University Medical Center - Heart Station | Nashville | Tennessee | 37232 | — |
| Vanderbilt University Medical Center - Radiology | Nashville | Tennessee | 37232 | — |
| Texas Clinical Research Institiute | Arlington | Texas | 76012 | — |
| Austin Gastroenterology PA/Professional Quality Research, Inc. | Austin | Texas | 78705 | — |
| Austin Gastroenterology PA | Austin | Texas | 78745 | — |
| Austin Endoscopy Center II | Austin | Texas | 78746 | — |
| Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Digestive Health Specialists of Tyler | Tyler | Texas | 75701 | — |
| VCU Health System Digestive Health Center | Richmond | Virginia | 23298 | — |
| VCU Health System Endoscopy Suite | Richmond | Virginia | 23298 | — |
| VCU Medical Center Investigational Drug Service (IDS) | Richmond | Virginia | 23298 | — |
| Virginia Commonwealth University, Clinical Research Services (CRSU) | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 120 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01458951, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 1, 2016 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01458951 live on ClinicalTrials.gov.