Study Of Dacomitinib (PF-00299804) In Advanced NSCLC Patients (Post Chemo Or Select First Line) To Evaluate Prophylactic Intervention On Derm And GI AEs And PRO
Public ClinicalTrials.gov record NCT01465802. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
ARCHER 1042: A PHASE 2 STUDY OF DACOMITINIB IN ADVANCED NON-SMALL CELL LUNG CANCER (POST-CHEMOTHERAPY OR SELECT FIRST LINE PATIENTS) TO EVALUATE PROPHYLACTIC INTERVENTION ON DERMATOLOGIC AND GASTROINTESTINAL ADVERSE EVENTS AND PATIENT REPORTED OUTCOMES
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To assess the impact of prophylactic treatment on the incidence of adverse events in advanced NSCLC patients (post chemotherapy) treated with dacomitinib daily as a single agent. To assess the impact of an interrupted dacomitinib dosing schedule in Cycle 1 on the incidence of adverse events in first-line advanced NSCLC patients with an EGFR mutation (HER-1 mutation, HER-2 mutation or HER-2 amplification).
Study identification
- NCT ID
- NCT01465802
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 236 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 26, 2011 (Actual)
- Primary completion
- May 18, 2015 (Actual)
- Completion
- May 18, 2015 (Actual)
- Last update posted
- Jan 9, 2019
2011 – 2015
United States locations
- U.S. sites
- 79
- U.S. states
- 20
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope | Duarte | California | 91010 | — |
| St. Jude Heritage Healthcare | Fullerton | California | 92835 | — |
| UCLA Hematology Oncology | Irvine | California | 92604 | — |
| UC San Diego Medical Center - La Jolla | La Jolla | California | 92037 | — |
| UC San Diego Moores Cancer Center - Investigational Drug Services | La Jolla | California | 92037 | — |
| UC San Diego Moores Cancer Center | La Jolla | California | 92093 | — |
| Drug Management Only: UCLA West Medical Pharmacy | Los Angeles | California | 90095-7349 | — |
| Drug Management Only: UCLA West Medical Pharmacy Attn: Steven L. Wong, Pharm.D. | Los Angeles | California | 90095 | — |
| Drug Management Only: UCLA West Medical Pharmacy | Los Angeles | California | 90095 | — |
| Drug Managment Only: UCLA West Medical Pharmacy | Los Angeles | California | 90095 | — |
| Regulatory Management Only TRIO-US Central Administration | Los Angeles | California | 90095 | — |
| Regulatory Management Only: TRIO-US Central Administration | Los Angeles | California | 90095 | — |
| Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | — |
| UCLA Hematology Oncology | Los Angeles | California | 90095 | — |
| Westwood Bowyer Clinic | Los Angeles | California | 90095 | — |
| UCLA/Pasadena HealthCare | Pasadena | California | 91105 | — |
| UC San Diego Medical Center - Hillcrest | San Diego | California | 92103 | — |
| Coastal Integrative Cancer Care | San Luis Obispo | California | 93401 | — |
| SANSUM Clinic | Santa Barbara | California | 93105 | — |
| Cancer Center of Santa Barbara with SANSUM Clinic | Santa Barbara | California | 93150 | — |
| Central Coast Medical Oncology Corporation | Santa Maria | California | 93454 | — |
| UCLA Hematology Oncology | Santa Monica | California | 90404 | — |
| UCLA Santa Monica Medical Center & Orthopaedic Hospital | Santa Monica | California | 90404 | — |
| Cancer Center of Santa Barbara with SANSUM Clinic | Solvang | California | 93463 | — |
| City of Hope South Pasadena Cancer Center | South Pasadena | California | 91030 | — |
| UCLA/Santa Clarita Valley Cancer Center | Valencia | California | 91355 | — |
| UCLA Cancer Center | Westlake Village | California | 91361 | — |
| Kaiser Permanente Colorado - Franklin | Denver | Colorado | 80205 | — |
| St. Mary's Hospital Regional Cancer Center | Grand Junction | Colorado | 81501 | — |
| Kaiser Permanente Colorado - Rock Creek | Lafayette | Colorado | 80026 | — |
| Kaiser Permanente Colorado - Lonetree | Lonetree | Colorado | 80124 | — |
| Michael and Dianne Bienes Comprehensive Cancer Center, Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| Memorial Cancer Institute | Hollywood | Florida | 33021 | — |
| Cancer Care of North Florida, PA | Lake City | Florida | 32024 | — |
| Memorial West Cancer Institute | Pembroke Pines | Florida | 33028 | — |
| University Cancer & Blood Center, LLC | Athens | Georgia | 30607 | — |
| Summit Cancer Care,PC | Savannah | Georgia | 31404 | — |
| Summit Cancer Care, PC | Savannah | Georgia | 31405 | — |
| Rush University Medical Center, Division of Hematology & Oncology | Chicago | Illinois | 60612 | — |
| Ships Drugs to: Emmanuel Semmes, RPh (or Ami Patel, Pharm D) University of Chicago | Chicago | Illinois | 60637 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Illinois CancerCare, P.C. | Peoria | Illinois | 61615 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| Josephine Ford Cancer Center-Downriver | Brownstown | Michigan | 48183 | — |
| Henry Ford Medical Center - Fairlane | Dearborn | Michigan | 48126 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Henry Ford Medical Center - Columbus | Novi | Michigan | 48377 | — |
| Henry Ford Hospital and Medical Center - West Bloomfield | West Bloomfield | Michigan | 48322 | — |
| The West Clinic, PC | Corinth | Mississippi | 38834 | — |
| The West Clinic, PC | Southaven | Mississippi | 38671 | — |
| Mercy Clinic Cancer & Hematology-Branson | Branson | Missouri | 65616 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Mercy Clinic Cancer and Hematology - Chub O-Reilly Cancer Center | Springfield | Missouri | 65807 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89128 | — |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | — |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Beth Israel Medical Center | New York | New York | 10003 | — |
| Beth Israel Comprehensive Cancer Center | New York | New York | 10011 | — |
| Columbia University Medical Center - The New York Presbyterian Hospital | New York | New York | 10032 | — |
| Stony Brook University Medical Center-Cancer Center | Stony Brook | New York | 11794-9447 | — |
| Montefiore-Einstein Center for Cancer Care | The Bronx | New York | 10461 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Carolina Oncology Specialists, PA | Hickory | North Carolina | 28602 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Legacy Pharma Research | Bismarck | North Dakota | 58501 | — |
| Mid Dakota Clinic, PC | Bismarck | North Dakota | 58501 | — |
| St Alexius Medical Center | Bismarck | North Dakota | 58501 | — |
| Charleston Hematology Oncology Associates, PA | Charleston | South Carolina | 29414 | — |
| The West Clinic, PC | Memphis | Tennessee | 38104 | — |
| The West Clinic, PC | Memphis | Tennessee | 38120 | — |
| Investigational Product Center (IPC) | Fort Worth | Texas | 76177 | — |
| Investigational Products Center (IPC) | Fort Worth | Texas | 76177 | — |
| 'Fletcher Allen Health Care, Inc | Burlington | Vermont | 05401 | — |
| Office of Clinical Trials Research, Fletcher Allen Health Care, Inc. | Burlington | Vermont | 05405 | — |
| Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | — |
| Swedish Cancer Institute - Issaquah | Issaquah | Washington | 98029 | — |
| Swedish Cancer Institute | Seattle | Washington | 98104 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01465802, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 9, 2019 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01465802 live on ClinicalTrials.gov.