Prevention of Serious Adverse Events Following Angiography
Public ClinicalTrials.gov record NCT01467466. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CSP #578 - Prevention of Serious Adverse Events Following Angiography (PRESERVE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this research study is to compare the effectiveness of intravenous isotonic sodium bicarbonate with intravenous isotonic sodium chloride and oral N-acetylcysteine (NAC) with oral placebo for the prevention of serious adverse outcomes following angiographic procedures in high-risk patients.
Study identification
- NCT ID
- NCT01467466
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 5,177 participants
Conditions and interventions
Interventions
- IV isotonic saline Drug
- IV isotonic bicarbonate Drug
- N-acetylcysteine Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 7, 2013 (Actual)
- Primary completion
- Sep 29, 2017 (Actual)
- Completion
- Oct 17, 2017 (Actual)
- Last update posted
- Nov 5, 2025
2013 – 2017
United States locations
- U.S. sites
- 35
- U.S. states
- 24
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Southern Arizona VA Health Care System, Tucson | Tucson | Arizona | 85723 | — |
| Central Arkansas VHS John L. McClellan Memorial Veterans Hospital, Little Rock, AR | Little Rock | Arkansas | 72205-5484 | — |
| VA Palo Alto Health Care System, Palo Alto, CA | Palo Alto | California | 94304-1290 | — |
| San Francisco VA Medical Center, San Francisco, CA | San Francisco | California | 94121 | — |
| VA Greater Los Angeles Healthcare System, West Los Angeles, CA | West Los Angeles | California | 90073 | — |
| Bay Pines VA Healthcare System, Pay Pines, FL | Bay Pines | Florida | 33708 | — |
| North Florida/South Georgia Veterans Health System, Gainesville, FL | Gainesville | Florida | 32608 | — |
| Charlie Norwood VA Medical Center, Augusta, GA | Augusta | Georgia | 30904 | — |
| Atlanta VA Medical and Rehab Center, Decatur, GA | Decatur | Georgia | 30033 | — |
| Jesse Brown VA Medical Center, Chicago, IL | Chicago | Illinois | 60612 | — |
| Richard L. Roudebush VA Medical Center, Indianapolis, IN | Indianapolis | Indiana | 46202-2884 | — |
| VA Boston Healthcare System West Roxbury Campus, West Roxbury, MA | West Roxbury | Massachusetts | 02132 | — |
| VA Ann Arbor Healthcare System, Ann Arbor, MI | Ann Arbor | Michigan | 48113 | — |
| Minneapolis VA Health Care System, Minneapolis, MN | Minneapolis | Minnesota | 55417 | — |
| Kansas City VA Medical Center, Kansas City, MO | Kansas City | Missouri | 64128 | — |
| St. Louis VA Medical Center John Cochran Division, St. Louis, MO | St Louis | Missouri | 63106 | — |
| New Mexico VA Health Care System, Albuquerque, NM | Albuquerque | New Mexico | 87108-5153 | — |
| VA Western New York Healthcare System, Buffalo, NY | Buffalo | New York | 14215 | — |
| Manhattan Campus of the VA NY Harbor Healthcare System, New York, NY | New York | New York | 10010 | — |
| Durham VA Medical Center, Durham, NC | Durham | North Carolina | 27705 | — |
| Cincinnati VA Medical Center, Cincinnati, OH | Cincinnati | Ohio | 45220 | — |
| Louis Stokes VA Medical Center, Cleveland, OH | Cleveland | Ohio | 44106 | — |
| Dayton VA Medical Center, Dayton, OH | Dayton | Ohio | 45428 | — |
| Oklahoma City VA Medical Center, Oklahoma City, OK | Oklahoma City | Oklahoma | 73104 | — |
| Portland VA Medical Center, Portland, OR | Portland | Oregon | 97201 | — |
| VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA | Pittsburgh | Pennsylvania | 15240 | — |
| Ralph H. Johnson VA Medical Center, Charleston, SC | Charleston | South Carolina | 29401-5799 | — |
| Memphis VA Medical Center, Memphis, TN | Memphis | Tennessee | 38104 | — |
| VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX | Dallas | Texas | 75216 | — |
| Michael E. DeBakey VA Medical Center, Houston, TX | Houston | Texas | 77030 | — |
| South Texas Health Care System, San Antonio, TX | San Antonio | Texas | 78229 | — |
| VA Salt Lake City Health Care System, Salt Lake City, UT | Salt Lake City | Utah | 84148 | — |
| Hunter Holmes McGuire VA Medical Center, Richmond, VA | Richmond | Virginia | 23249 | — |
| Salem VA Medical Center, Salem, VA | Salem | Virginia | 24153 | — |
| VA Puget Sound Health Care System Seattle Division, Seattle, WA | Seattle | Washington | 98108 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01467466, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 5, 2025 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01467466 live on ClinicalTrials.gov.