Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY)
Public ClinicalTrials.gov record NCT01479283. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY): A Multi-Center International Randomized Controlled Trial Comparing Alternative Antibiotic Regimens in Patients Undergoing Tumor Resections With Endoprosthetic Replacements
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) trial is the first ever international multi-center randomized controlled trial in bone cancer surgery. In order to avoid amputation for bone cancer in the leg, complex limb-saving operations are performed. However, infections with devastating complications following surgery are common. Surgeons from across the world will randomize patients to receive either short- or long-duration antibiotic regimens after surgery with the goal of identifying the best regimen to reduce these infections.
Study identification
- NCT ID
- NCT01479283
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 602 participants
Conditions and interventions
Conditions
Interventions
- 24-Hour Prophylactic Cefazolin* Antibiotic Regimen Drug
- 5-Days Prophylactic Cefazolin* Antibiotic Regimen Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2013 (Actual)
- Primary completion
- Mar 2021 (Actual)
- Completion
- Mar 2021 (Actual)
- Last update posted
- Mar 11, 2021
2013 – 2021
United States locations
- U.S. sites
- 34
- U.S. states
- 18
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Ronald Reagan UCLA Medical Center | Los Angeles | California | 90404 | — |
| Stanford University Hospital and Clinics | Redwood City | California | 94063 | — |
| UC Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| University of California San Francisco Medical Center | San Francisco | California | 94118 | — |
| University of Connecticut Health Center | Farmington | Connecticut | 06030 | — |
| Hartford Hospital | Hartford | Connecticut | 06106 | — |
| University of Florida Health Shands Hospital | Gainesville | Florida | 32611-2727 | — |
| Emory Orthopaedics and Spine Center | Atlanta | Georgia | 30329 | — |
| Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| Franklin Square Medical Center | Baltimore | Maryland | 21237 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| University of Minnesota Medical Center | Minneapolis | Minnesota | 55454 | — |
| Saint Louis University Hospital | St Louis | Missouri | 63110 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Albany Medical Center | Albany | New York | 11206 | — |
| SUNY Upstate University Hospital | East Syracuse | New York | 13057 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| Long Island Jewish Medical Center | Northwell Health | Queens | New York | 11040 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Cincinnati Children's Hospital | Cincinnati | Ohio | 45229 | — |
| The Cleveland Clinic - Hillcrest Hospital | Cleveland | Ohio | 44195 | — |
| Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University Hospital | Portland | Oregon | 97239 | — |
| The Rothman Institute at Jefferson | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt Medical Center | Nashville | Tennessee | 37232-8774 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
| Medical College of Wisconsin - Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01479283, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 11, 2021 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01479283 live on ClinicalTrials.gov.