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Completed Phase 2 Interventional Results available

Losartan to Reverse Sickle Nephropathy

ClinicalTrials.gov ID: NCT01479439

Public ClinicalTrials.gov record NCT01479439. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 6:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Trial of Losartan to Reverse Sickle Nephropathy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Sickle cell disease causes kidney damage with increasing age, leading to chronic kidney disease and renal failure in nearly one third of patients with sickle cell disease. Currently, there is no treatment for sickle cell related kidney disease.

Study identification

NCT ID
NCT01479439
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
36 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
6 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 2012 (Type not available)
Primary completion
Nov 2015 (Actual)
Completion
Dec 2015 (Actual)
Last update posted
Sep 29, 2020

2012 – 2015

United States locations

U.S. sites
9
U.S. states
5
U.S. cities
8
Facility City State ZIP Site status
University of Illinois at Chicago Chicago Illinois 60612 —
University of Louisville Louisville Kentucky 40201 —
NHLBI Bethesda Maryland 20892 —
Akron Children's Hospital Akron Ohio 44308 —
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 —
University of Cincinnati Cincinnati Ohio 45229 —
Nationwide Children's Hospital Columbus Ohio 43205 —
University of Texas Southwestern Dallas Texas 75390 —
Texas Children's Hospital Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01479439, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 29, 2020 · Synced Oct 22, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01479439 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →