Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

A Study to Assess the Effect and Safety of AZD6765 in Patients With Major Depressive Disorder

ClinicalTrials.gov ID: NCT01482221

Public ClinicalTrials.gov record NCT01482221. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 8:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled, Phase IIb Efficacy and Safety Study of Adjunctive AZD6765 in Patients With Major Depressive Disorder (MDD) and a History of Inadequate Response to Antidepressants

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the effect and safety of AZD6765 in patients with major depressive disorder who exhibit inadequate response to antidepressants. AZD6765 is a channel blocker of the N-methyl-D-aspartate (NMDA) class of glutamate receptors.

Study identification

NCT ID
NCT01482221
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
542 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 16, 2011 (Actual)
Primary completion
Aug 26, 2013 (Actual)
Completion
Aug 26, 2013 (Actual)
Last update posted
Apr 11, 2017

2011 – 2013

United States locations

U.S. sites
33
U.S. states
17
U.S. cities
33
Facility City State ZIP Site status
Research Site Chino California — —
Research Site Lond Beach California — —
Research Site San Diego California — —
Research Site Stanford California — —
Research Site New Heaven Connecticut — —
Research Site Fort Lauderdale Florida — —
Research Site Gainsville Florida — —
Research Site Lake City Florida — —
Research Site Miami Florida — —
Research Site Orlando Florida — —
Research Site St. Petersburg Florida — —
Research Site Atlanta Georgia — —
Research Site Decatur Georgia — —
Research Site Hoffman Estates Illinois — —
Research Site Joliet Illinois — —
Research Site Skokie Illinois — —
Research Site Lake Charles Louisiana — —
Research Site Shreveport Louisiana — —
Research Site Baltimore Maryland — —
Research Site Boston Massachusetts — —
Research Site Minneapolis Minnesota — —
Research Site St Louis Missouri — —
Research Site Willingboro New Jersey — —
Research Site Mount Kisco New York — —
Research Site New York New York — —
Research Site Rochester New York — —
Research Site Winston-Salem North Carolina — —
Research Site Cincinnati Ohio — —
Research Site Dayton Ohio — —
Research Site Philadelphia Pennsylvania — —
Research Site Dallas Texas — —
Research Site Houston Texas — —
Research Site Bellevue Washington — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01482221, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 11, 2017 · Synced Oct 17, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01482221 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →