A Study to Investigate the Safety and Clinical Effect of Nexagon® as a Topical Treatment for Subjects With a Diabetic Foot Ulcer (DUNE)
Public ClinicalTrials.gov record NCT01490879. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Prospective, Double-blind, Vehicle-controlled, Dose-ranging, Multi-center Study to Assess the Safety and Clinical Effect of Nexagon® in the Treatment of Subjects With a Diabetic Foot Ulcer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is for Type I or Type II diabetic subjects with with a diabetic foot ulcer. The study is being done to determine if Nexagon® plus standard of care is more effective than placebo plus standard of care. Standard of care will include debridement of the ulcer, standardized dressings and standardized off-loading using a Removable Cast Walker.
Study identification
- NCT ID
- NCT01490879
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 168 participants
Conditions and interventions
Conditions
Interventions
- Nexagon® Low Dose Drug
- Nexagon® Medium Dose Drug
- Nexagon® High Dose Drug
- Nexagon® vehicle Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2012
- Primary completion
- Jan 31, 2014
- Completion
- Mar 31, 2014
- Last update posted
- Apr 30, 2014
2012 – 2014
United States locations
- U.S. sites
- 9
- U.S. states
- 5
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Foot and Ankle Specialists, LLC | Phoenix | Arizona | 85015 | — |
| University of Arizona Medical Center | Tucson | Arizona | 85724 | — |
| Center For Clinical Research Inc. | Castro Valley | California | 94546 | — |
| Advanced Foot Care and Clinical Research Center | Fresno | California | 93722 | — |
| Barry University Clinical Research | Hialeah | Florida | 33013 | — |
| Univeristy of Miami, Miller School of Medicine, Dermatology Research | Miami | Florida | 33136 | — |
| Doctors Research Network | South Miami | Florida | 33143 | — |
| Advanced Foot and Ankle Center | Las Vegas | Nevada | 89119 | — |
| Houston Foot and Ankle Care | Houston | Texas | 77074 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01490879, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 30, 2014 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01490879 live on ClinicalTrials.gov.