A Study of Pertuzumab in Combination With Trastuzumab Plus an Aromatase Inhibitor in Participants With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive and Hormone Receptor-Positive Advanced Breast Cancer
Public ClinicalTrials.gov record NCT01491737. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Two-Arm, Open-Label, Multicenter Phase II Trial Assessing the Efficacy and Safety of Pertuzumab Given in Combination With Trastuzumab Plus an Aromatase Inhibitor in First Line Patients With HER2-Positive and Hormone Receptor-Positive Advanced (Metastatic or Locally Advanced) Breast Cancer
Study identification
- NCT ID
- NCT01491737
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 258 participants
Conditions and interventions
Conditions
Interventions
- Pertuzumab Drug
- Trastuzumab Drug
- Aromatase Inhibitor Drug
- Induction Chemotherapy Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 16, 2012
- Primary completion
- Mar 16, 2016
- Completion
- Nov 13, 2019
- Last update posted
- Oct 27, 2020
2012 – 2019
United States locations
- U.S. sites
- 21
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| Ironwood Cancer TX & Rsch Ctrs | Chandler | Arizona | 85224 | — |
| Genesis Cancer Center | Hot Springs | Arkansas | 71913 | — |
| Comprehensive Blood & CA Ctr; Research | Bakersfield | California | 93309 | — |
| Rocky Mountain Cancer Center - Denver | Denver | Colorado | 80220 | — |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Advanced Medical Specialties | Miami | Florida | 33176 | — |
| Georgia Cancer Specialists - Northside | Atlanta | Georgia | 30341 | — |
| Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital | Marietta | Georgia | 30060 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214-3728 | — |
| Crescent City Rsrch Cnsrtm, LLC | Marrero | Louisiana | 70072 | — |
| Weinberg CA Inst Franklin Sq | Baltimore | Maryland | 21237 | — |
| Center For Cancer and Blood Disorders | Bethesda | Maryland | 20817 | — |
| Washington University School of Medicine; Internal Medicine - Renal | St Louis | Missouri | 63110 | — |
| Hematology Oncology Associates; Carol G. Simon Ctr | Morristown | New Jersey | 07960 | — |
| Cooper Hospital; Hematology & Oncology | Voorhees Township | New Jersey | 08043 | — |
| NS-Long Island Jewish Hlth Sys | Lake Success | New York | 11042 | — |
| ProHEALTH Care Associates LLP | Lake Success | New York | 11042 | — |
| UPMC Cancer Centers | Pittsburgh | Pennsylvania | 15232 | — |
| Baylor College of Medicine; Lester & Sue Smith Breast Ctr | Houston | Texas | 77030 | — |
| Scott and White Hospital; Cancer Center | Temple | Texas | 76508 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 61 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01491737, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 27, 2020 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01491737 live on ClinicalTrials.gov.