ClinicalTrials.gov record
A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin
ClinicalTrials.gov ID: NCT01492361
Public ClinicalTrials.gov record NCT01492361. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Evaluation of the Effect of AMR101 on Cardiovascular Health and Mortality in Hypertriglyceridemic Patients With Cardiovascular Disease or at High Risk for Cardiovascular Disease: REDUCE-IT (Reduction of Cardiovascular Events With EPA - Intervention Trial)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
AMR101 (icosapent ethyl \[ethyl-EPA\]) is a highly purified ethyl ester of eicosapentaenoic acid (EPA) developed by Amarin Pharma Inc. for the treatment of cardiovascular disease in statin-treated patients with hypertriglyceridemia. The purpose of this study was to evaluate whether this drug, combined with a statin therapy, will be superior to the statin therapy alone, when used as a prevention in reducing long-term cardiovascular events in high-risk patients with mixed dyslipidemia.
Study identification
- NCT ID
- NCT01492361
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 8,179 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2011 (Actual)
- Primary completion
- May 2018 (Actual)
- Completion
- May 2018 (Actual)
- Last update posted
- Apr 14, 2022
2011 – 2018
United States locations
- U.S. sites
- 176
- U.S. states
- 43
- U.S. cities
- 157
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Amarin Investigational Site | Birmingham | Alabama | 35205 | — |
| Amarin Investigational Site | Birmingham | Alabama | 35235 | — |
| Amarin Investigational Site | Huntsville | Alabama | 35801 | — |
| Amarin Investigational Site | Mobile | Alabama | 36608 | — |
| Amarin Investigational Site | Muscle Shoals | Alabama | 35662 | — |
| Amarin Investigational Site | Mesa | Arizona | 85206 | — |
| Amarin Investigational Site | Phoenix | Arizona | 85251 | — |
| Amarin Investigational Site | Tucson | Arizona | 85745 | — |
| Amarin Investigational Site | Little Rock | Arkansas | 72204 | — |
| Amarin Investigational Site | Beverly Hills | California | 90211 | — |
| Amarin Investigational Site | Chino | California | 91710 | — |
| Amarin Investigational Site | Concord | California | 94520 | — |
| Amarin Investigational Site | El Cajon | California | 92020 | — |
| Amarin Investigational Site | Encino | California | 91436 | — |
| Amarin Investigational Site | Fair Oaks | California | 95628 | — |
| Amarin Investigational Site | Hawaiian Gardens | California | 90716 | — |
| Amarin Investigational Site | Lancaster | California | 93534 | — |
| Amarin Investigational Site | Lincoln | California | 95648 | — |
| Amarin Investigational Site | Los Angeles | California | 90015 | — |
| Amarin Investigational Site | Los Angeles | California | 90017 | — |
| Amarin Investigational Site | Los Angeles | California | 90033 | — |
| Amarin Investigational Site | National City | California | 91950 | — |
| Amarin Investigational Site | Orange | California | 92868 | — |
| Amarin Investigational Site | Paramount | California | 90723 | — |
| Amarin Investigational Site | Roseville | California | 95661 | — |
| Amarin Investigational Site | San Diego | California | 92123 | — |
| Amarin Investigational Site | Torrance | California | 90502 | — |
| Amarin Investigational Site | Ventura | California | 93003 | — |
| Amarin Investigational Site | Walnut Creek | California | 94598 | — |
| Amarin Investigational Site | Aurora | Colorado | 80012 | — |
| Amarin Investigational Site | Colorado Springs | Colorado | 80909 | — |
| Amarin Investigational Site | Golden | Colorado | 80401 | — |
| Amarin Investigational Site | Guilford | Connecticut | 06437 | — |
| Amarin Investigational Site | Hartford | Connecticut | 06102 | — |
| Amarin Investigational Site | Newark | Delaware | 19718 | — |
| Amarin Investigational Site | Wilmington | Delaware | 19803 | — |
| Amarin Investigational Site | Washington D.C. | District of Columbia | 20037 | — |
| Amarin Investigational Site | Boynton Beach | Florida | 33437 | — |
| Amarin Investigational Site | Bradenton | Florida | 34209 | — |
| Amarin Investigational Site | Clearwater | Florida | 33756 | — |
| Amarin Investigational Site | Edgewater | Florida | 32132 | — |
| Amarin Investigational Site | Fleming Island | Florida | 32003 | — |
| Amarin Investigational Site | Fort Lauderdale | Florida | 33308 | — |
| Amarin Investigational Site | Fort Lauderdale | Florida | 33312 | — |
| Amarin Investigational Site | Inverness | Florida | 34429 | — |
| Amarin Investigational Site | Jacksonville | Florida | 32204 | — |
| Amarin Investigational Site | Jacksonville | Florida | 32205 | — |
| Amarin Investigational Site | Jacksonville | Florida | 32207 | — |
| Amarin Investigational Site | Jacksonville | Florida | 32216 | — |
| Amarin Investigational Site | Miami | Florida | 33144 | — |
| Amarin Investigational Site | Miami | Florida | 33175 | — |
| Amarin Investigational Site | Miami Beach | Florida | 33140 | — |
| Amarin Investigational Site | Miami Lakes | Florida | 33014 | — |
| Amarin Investigational Site | Ocala | Florida | 34471 | — |
| Amarin Investigational Site | Orlando | Florida | 32803 | — |
| Amarin Investigational Site | Pembroke Pines | Florida | 33026 | — |
| Amarin Investigational Site | Plantation | Florida | 33324 | — |
| Amarin Investigational Site | Safety Harbor | Florida | 34695 | — |
| Amarin Investigational Site | Sarasota | Florida | 34233 | — |
| Amarin Investigational Site | St. Petersburg | Florida | 33713 | — |
| Amarin Investigational Site | Vero Beach | Florida | 32960 | — |
| Amarin Investigational Site | West Palm Beach | Florida | 33401 | — |
| Amarin Investigational Site | Conyers | Georgia | 30094 | — |
| Amarin Investigational Site | Covington | Georgia | 30014 | — |
| Amarin Investigational Site | Cumming | Georgia | 30041 | — |
| Amarin Investigational Site | Roswell | Georgia | 30076 | — |
| Amarin Investigational Site | Honolulu | Hawaii | 96818 | — |
| Amarin Investigational Site | Addison | Illinois | 60101 | — |
| Amarin Investigational Site | Chicago | Illinois | 60611 | — |
| Amarin Investigational Site | Norman | Illinois | 61761 | — |
| Amarin Investigational Site | North Chicago | Illinois | 60064 | — |
| Amarin Investigational Site | Peoria | Illinois | 61636 | — |
| Amarin Investigational Site | Winfield | Illinois | 60190 | — |
| Amarin Investigational Site | Evansville | Indiana | 47713 | — |
| Amarin Investigational Site | Iowa City | Iowa | 52242 | — |
| Amarin Investigational Site | Wichita | Kansas | 67203 | — |
| Amarin Investigational Site | Wichita | Kansas | 67207 | — |
| Amarin Investigational Site | Louisville | Kentucky | 40213 | — |
| Amarin Investigational Site | Alexandria | Louisiana | 71301 | — |
| Amarin Investigational Site | Eunice | Louisiana | 70535 | — |
| Amarin Investigational Site | Marrero | Louisiana | 70072 | — |
| Amarin Investigational Site | Auburn | Maine | 04210 | — |
| Amarin Investigational Site | Baltimore | Maryland | 21236 | — |
| Amarin Investigational Site | Lutherville | Maryland | 21093 | — |
| Amarin Investigational Site | Takoma Park | Maryland | 20912 | — |
| Amarin Investigational Site | Boston | Massachusetts | 02118 | — |
| Amarin Investigational Site | Boston | Massachusetts | 02215 | — |
| Amarin Investigational Site | Fall River | Massachusetts | 02721 | — |
| Amarin Investigational Site | Lansing | Michigan | 48910 | — |
| Amarin Investigational Site | Marquette | Michigan | 49855 | — |
| Amarin Investigational Site | Troy | Michigan | 48098 | — |
| Amarin Investigational Site | Saint Cloud | Minnesota | 56303 | — |
| Amarin Investigational Site | Biloxi | Mississippi | 39531 | — |
| Amarin Investigational Site | Tupelo | Mississippi | 38801 | — |
| Amarin Investigational Site | Chesterfield | Missouri | 63141 | — |
| Amarin Investigational Site | City of Saint Peters | Missouri | 63303 | — |
| Amarin Investigational Site | Florissant | Missouri | 63031 | — |
| Amarin Investigational Site | Jefferson City | Missouri | 65109 | — |
| Amarin Investigational Site | Kansas City | Missouri | 64114 | — |
| Amarin Investigational Site | St Louis | Missouri | 63110 | — |
| Amarin Investigational Site | Hastings | Nebraska | 68901 | — |
| Amarin Investigational Site | Omaha | Nebraska | 68114 | — |
| Amarin Investigational Site | Omaha | Nebraska | 68154 | — |
| Amarin Investigational Site | Henderson | Nevada | 89052 | — |
| Amarin Investigational Site | Las Vegas | Nevada | 89101 | — |
| Amarin Investigational Site | Ocean City | New Jersey | 07712 | — |
| Amarin Investigational Site | Albuquerque | New Mexico | 87102 | — |
| Amarin Investigational Site | Albany | New York | 12206 | — |
| Amarin Investigational Site | Brooklyn | New York | 11206 | — |
| Amarin Investigational Site | Great Neck | New York | 11023 | — |
| Amarin Investigational Site | Liverpool | New York | 13088 | — |
| Amarin Investigational Site | New York | New York | 10001 | — |
| Amarin Investigational Site | New York | New York | 10016 | — |
| Amarin Investigational Site | North Massapequa | New York | 11758 | — |
| Amarin Investigational Site | Smithtown | New York | 11787 | — |
| Amarin Investigational Site | Vestal | New York | 13850 | — |
| Amarin Investigational Site | West Seneca | New York | 14224 | — |
| Amarin Investigational Site | Charlotte | North Carolina | 28204 | — |
| Amarin Investigational Site | Durham | North Carolina | 27710 | — |
| Amarin Investigational Site | Gastonia | North Carolina | 28054 | — |
| Amarin Investigational Site | Kernersville | North Carolina | 27284 | — |
| Amarin Investigational Site | Raleigh | North Carolina | 27609 | — |
| Amarin Investigational Site | Winston-Salem | North Carolina | 27157 | — |
| Amarin Investigational Site | Fargo | North Dakota | 58103 | — |
| Amarin Investigational Site | Cincinnati | Ohio | 45219 | — |
| Amarin Investigational Site | Dayton | Ohio | 45419 | — |
| Amarin Investigational Site | Lorain | Ohio | 44053 | — |
| Amarin Investigational Site | Sandusky | Ohio | 44870 | — |
| Amarin Investigational Site | Tulsa | Oklahoma | 74104 | — |
| Amarin Investigational Site | Bend | Oregon | 97702 | — |
| Amarin Investigational Site | Portland | Oregon | 97239 | — |
| Amarin Investigational Site | Beaver | Pennsylvania | 15009 | — |
| Amarin Investigational Site | Doylestown | Pennsylvania | 18901 | — |
| Amarin Investigational Site | Jersey Shore | Pennsylvania | 17740 | — |
| Amarin Investigational Site | Newport | Pennsylvania | 17074 | — |
| Amarin Investigational Site | Philadelphia | Pennsylvania | 19104 | — |
| Amarin Investigational Site | Phoenixville | Pennsylvania | 19460 | — |
| Amarin Investigational Site | Sellersville | Pennsylvania | 18960 | — |
| Amarin Investigational Site | Tipton | Pennsylvania | 16684 | — |
| Amarin Investigational Site | Wyomissing | Pennsylvania | 19610 | — |
| Amarin Investigational Site | Yardley | Pennsylvania | 19067 | — |
| Amarin Investigational Site | Lancaster | South Carolina | 29720 | — |
| Amarin Investigational Site | Simpsonville | South Carolina | 29681 | — |
| Amarin Investigational Site | Rapid City | South Dakota | 57701 | — |
| Amarin Investigational Site | Bristol | Tennessee | 37620 | — |
| Amarin Investigational Site | Columbia | Tennessee | 38401 | — |
| Amarin Investigational Site | Germantown | Tennessee | 38138 | — |
| Amarin Investigational Site | Jackson | Tennessee | 38301 | — |
| Amarin Investigational Site | Knoxville | Tennessee | 37917 | — |
| Amarin Investigational Site | Smyrna | Tennessee | 37167 | — |
| Amarin Investigational Site | Austin | Texas | 78756 | — |
| Amarin Investigational Site | Beaumont | Texas | 77702 | — |
| Amarin Investigational Site | Carrollton | Texas | 75007 | — |
| Amarin Investigational Site | Dallas | Texas | 75231 | — |
| Amarin Investigational Site | Houston | Texas | 77024 | — |
| Amarin Investigational Site | Houston | Texas | 77025 | — |
| Amarin Investigational Site | Houston | Texas | 77030 | — |
| Amarin Investigational Site | Houston | Texas | 77053 | — |
| Amarin Investigational Site | Houston | Texas | 77070 | — |
| Amarin Investigational Site | Houston | Texas | 77077 | — |
| Amarin Investigational Site | Houston | Texas | 77079 | — |
| Amarin Investigational Site | Hurst | Texas | 76054 | — |
| Amarin Investigational Site | New Braunfels | Texas | 78130 | — |
| Amarin Investigational Site | Plano | Texas | 75075 | — |
| Amarin Investigational Site | San Antonio | Texas | 78228 | — |
| Amarin Investigational Site | San Antonio | Texas | 78238 | — |
| Amarin Investigational Site | Splendora | Texas | 77372 | — |
| Amarin Investigational Site | Tomball | Texas | 77375 | — |
| Amarin Investigational Site | West Jordan | Utah | 84088 | — |
| Amarin Investigational Site | Falls Church | Virginia | 22044 | — |
| Amarin Investigational Site | Manassas | Virginia | 20109 | — |
| Amarin Investigational Site | Midlothian | Virginia | 23114 | — |
| Amarin Investigational Site | Newport News | Virginia | 23606 | — |
| Amarin Investigational Site | Burien | Washington | 98166 | — |
| Amarin Investigational Site | Tacoma | Washington | 98405 | — |
| Amarin Investigational Site | Huntington | West Virginia | 25701 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 234 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01492361, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 14, 2022 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01492361 live on ClinicalTrials.gov.