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Completed Phase 1 Interventional

Study to Evaluate the Safety, Tolerability and the Effect of BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects With Mild Alzheimer's Disease

ClinicalTrials.gov ID: NCT01492374

Public ClinicalTrials.gov record NCT01492374. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 14, 2026, 8:05 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability and the Effect of BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects With Mild Alzheimer's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to evaluate safety and the pharmacodynamic effects of BMS-241027 on cerebrospinal fluid (CSF) Tau, connectivity magnetic resonance imaging (MRI), and computerized cognitive tests in mild Alzheimer's disease (AD) subjects, following 9 weekly intravenous (IV) infusions of BMS-241027

Study identification

NCT ID
NCT01492374
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
40 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 2012 (Type not available)
Primary completion
Oct 2013 (Actual)
Completion
Oct 2013 (Actual)
Last update posted
Jul 24, 2014

2012 – 2013

United States locations

U.S. sites
15
U.S. states
10
U.S. cities
14
Facility City State ZIP Site status
Anaheim Clinical Trials Llc Anaheim California 92801 —
Not listed Long Beach California 90806 —
Ucsf Memory And Aging Center San Francisco California 94158 —
Alpine Clinical Research Center, Inc. Boulder Colorado 80304 —
Associated Neurologists Of Southern Connecticut, P.C. Fairfield Connecticut 06824 —
Compass Research, Llc Orlando Florida 32806 —
Palm Beach Neurological Center Advanced Research Consultants Palm Beach Gardens Florida 33410 —
Alexian Brothers Neurosciences Institute Clinical Research Elk Grove Village Illinois 60007 —
Brigham And Women'S Hospital Boston Massachusetts 02115 —
Michigan State University East Lansing Michigan 48824 —
The Ohio State University Columbus Ohio 43210 —
The Clinical Trial Center, Llc Jenkintown Pennsylvania 19046 —
Hospital Of The University Of Pennsylvania Philadelphia Pennsylvania 19104 —
Penn Memory Center Philadelphia Pennsylvania 19104 —
Lifetree Clinical Research Salt Lake City Utah 84106 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01492374, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 24, 2014 · Synced Oct 14, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01492374 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →