ClinicalTrials.gov record
TRINOVA-3: A Study of AMG 386 or AMG 386 Placebo in Combination With Paclitaxel and Carboplatin to Treat Ovarian Cancer
ClinicalTrials.gov ID: NCT01493505
Public ClinicalTrials.gov record NCT01493505. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 19, 2026, 6:09 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-blind, Placebo-controlled, Multicenter Study of AMG 386 With Paclitaxel and Carboplatin as First-line Treatment of Subjects With FIGO Stage III-IV Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancers
Study identification
- NCT ID
- NCT01493505
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 1,015 participants
Conditions and interventions
Conditions
Interventions
- AMG 386 Drug
- AMG 386 Placebo Drug
- Carboplatin Drug
- Paclitaxel Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2011
- Primary completion
- Feb 29, 2016
- Completion
- Nov 30, 2016
- Last update posted
- Feb 22, 2017
2012 – 2016
United States locations
- U.S. sites
- 173
- U.S. states
- 45
- U.S. cities
- 145
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35233 | — |
| Research Site | Mobile | Alabama | 36604 | — |
| Research Site | Anchorage | Alaska | 99508 | — |
| Research Site | Gilbert | Arizona | 85234 | — |
| Research Site | Peoria | Arizona | 85381 | — |
| Research Site | Phoenix | Arizona | 85013 | — |
| Research Site | Phoenix | Arizona | 85016 | — |
| Research Site | Tucson | Arizona | 85710 | — |
| Research Site | Tucson | Arizona | 85724-5024 | — |
| Research Site | Berkeley | California | 94704 | — |
| Research Site | Burbank | California | 91505 | — |
| Research Site | Concord | California | 94520 | — |
| Research Site | Corona | California | 92879 | — |
| Research Site | La Jolla | California | 92093-0957 | — |
| Research Site | Long Beach | California | 90806 | — |
| Research Site | Los Angeles | California | 90027 | — |
| Research Site | Orange | California | 92868 | — |
| Research Site | Oxnard | California | 93030 | — |
| Research Site | Rancho Mirage | California | 92270 | — |
| Research Site | Sacramento | California | 95816 | — |
| Research Site | Sacramento | California | 95817 | — |
| Research Site | San Diego | California | 92123 | — |
| Research Site | Aurora | Colorado | 80045 | — |
| Research Site | Englewood | Colorado | 80113 | — |
| Research Site | Bridgeport | Connecticut | 06606 | — |
| Research Site | Farmington | Connecticut | 06030 | — |
| Research Site | Hartford | Connecticut | 06106 | — |
| Research Site | New Britain | Connecticut | 06050 | — |
| Research Site | Stamford | Connecticut | 06902 | — |
| Research Site | Clearwater | Florida | 33756 | — |
| Research Site | Hollywood | Florida | 33021 | — |
| Research Site | Miami | Florida | 33146 | — |
| Research Site | Orlando | Florida | 32804 | — |
| Research Site | Orlando | Florida | 32806 | — |
| Research Site | St. Petersburg | Florida | 33701 | — |
| Research Site | Tampa | Florida | 33612 | — |
| Research Site | Augusta | Georgia | 30912 | — |
| Research Site | Gainesville | Georgia | 30501 | — |
| Research Site | Macon | Georgia | 31201 | — |
| Research Site | Savannah | Georgia | 31404 | — |
| Research Site | Honolulu | Hawaii | 96826 | — |
| Research Site | Chicago | Illinois | 60611 | — |
| Research Site | Chicago | Illinois | 60612 | — |
| Research Site | Chicago | Illinois | 60637 | — |
| Research Site | Decatur | Illinois | 62526 | — |
| Research Site | Evanston | Illinois | 60201 | — |
| Research Site | Hinsdale | Illinois | 60521 | — |
| Research Site | Joliet | Illinois | 60435 | — |
| Research Site | Maywood | Illinois | 60153 | — |
| Research Site | Oak Lawn | Illinois | 60453 | — |
| Research Site | Park Ridge | Illinois | 60068 | — |
| Research Site | Urbana | Illinois | 61801 | — |
| Research Site | Indianapolis | Indiana | 46202 | — |
| Research Site | Indianapolis | Indiana | 46237 | — |
| Research Site | Indianapolis | Indiana | 46260 | — |
| Research Site | Munster | Indiana | 46321 | — |
| Research Site | South Bend | Indiana | 46628 | — |
| Research Site | Ames | Iowa | 50010 | — |
| Research Site | Iowa City | Iowa | 52242 | — |
| Research Site | Kansas City | Kansas | 66160 | — |
| Research Site | Edgewood | Kentucky | 41017 | — |
| Research Site | Lexington | Kentucky | 40536 | — |
| Research Site | Covington | Louisiana | 70433 | — |
| Research Site | Lafayette | Louisiana | 70503 | — |
| Research Site | Scarborough | Maine | 04074 | — |
| Research Site | Baltimore | Maryland | 21204 | — |
| Research Site | Baltimore | Maryland | 21215 | — |
| Research Site | Baltimore | Maryland | 21237 | — |
| Research Site | Boston | Massachusetts | 02114 | — |
| Research Site | Burlington | Massachusetts | 01805 | — |
| Research Site | Danvers | Massachusetts | 01923 | — |
| Research Site | Worcester | Massachusetts | 01605 | — |
| Research Site | Detroit | Michigan | 48201 | — |
| Research Site | Detroit | Michigan | 48202 | — |
| Research Site | Kalamazoo | Michigan | 49007 | — |
| Research Site | Minneapolis | Minnesota | 55416 | — |
| Research Site | Rochester | Minnesota | 55905 | — |
| Research Site | Saint Louis Park | Minnesota | 55426 | — |
| Research Site | Jackson | Mississippi | 39216 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | St Louis | Missouri | 63110 | — |
| Research Site | Billings | Montana | 59101 | — |
| Research Site | Lincoln | Nebraska | 68506 | — |
| Research Site | Las Vegas | Nevada | 89169 | — |
| Research Site | Reno | Nevada | 89502 | — |
| Research Site | Lebanon | New Hampshire | 03756 | — |
| Research Site | Hackensack | New Jersey | 07601 | — |
| Research Site | Neptune City | New Jersey | 07753 | — |
| Research Site | Voorhees Township | New Jersey | 08043 | — |
| Research Site | Albuquerque | New Mexico | 87102 | — |
| Research Site | Albuquerque | New Mexico | 87131 | — |
| Research Site | Albany | New York | 12208 | — |
| Research Site | Brightwaters | New York | 11718 | — |
| Research Site | Buffalo | New York | 14263 | — |
| Research Site | Jamaica | New York | 11432 | — |
| Research Site | Lake Success | New York | 11042 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | New York | New York | 10032 | — |
| Research Site | New York | New York | 10065 | — |
| Research Site | Syracuse | New York | 13210 | — |
| Research Site | The Bronx | New York | 10461 | — |
| Research Site | Asheville | North Carolina | 28806 | — |
| Research Site | Burlington | North Carolina | 27215 | — |
| Research Site | Chapel Hill | North Carolina | 27599-7570 | — |
| Research Site | Charlotte | North Carolina | 28204 | — |
| Research Site | Concord | North Carolina | 28025 | — |
| Research Site | Durham | North Carolina | 27710 | — |
| Research Site | Wilmington | North Carolina | 28402 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Winston-Salem | North Carolina | 27157 | — |
| Research Site | Fargo | North Dakota | 58122 | — |
| Research Site | Akron | Ohio | 44304 | — |
| Research Site | Canton | Ohio | 44710 | — |
| Research Site | Cincinnati | Ohio | 45220 | — |
| Research Site | Cincinnati | Ohio | 45267-0457 | — |
| Research Site | Cleveland | Ohio | 44106 | — |
| Research Site | Cleveland | Ohio | 44109 | — |
| Research Site | Cleveland | Ohio | 44195 | — |
| Research Site | Columbus | Ohio | 43210 | — |
| Research Site | Columbus | Ohio | 43214 | — |
| Research Site | Kettering | Ohio | 45429 | — |
| Research Site | Mayfield Heights | Ohio | 44124 | — |
| Research Site | Toledo | Ohio | 43614 | — |
| Research Site | Oklahoma City | Oklahoma | 73104 | — |
| Research Site | Tulsa | Oklahoma | 74136 | — |
| Research Site | Bend | Oregon | 97701 | — |
| Research Site | Abington | Pennsylvania | 19001 | — |
| Research Site | Bethlehem | Pennsylvania | 18015 | — |
| Research Site | Philadelphia | Pennsylvania | 19104 | — |
| Research Site | Philadelphia | Pennsylvania | 19107 | — |
| Research Site | Pittsburgh | Pennsylvania | 15213 | — |
| Research Site | Pittsburgh | Pennsylvania | 15224 | — |
| Research Site | Radnor | Pennsylvania | 19087 | — |
| Research Site | West Reading | Pennsylvania | 19611 | — |
| Research Site | Providence | Rhode Island | 02905 | — |
| Research Site | Charleston | South Carolina | 29425 | — |
| Research Site | Columbia | South Carolina | 29210 | — |
| Research Site | Greenville | South Carolina | 29601 | — |
| Research Site | Greenville | South Carolina | 29605 | — |
| Research Site | Sioux Falls | South Dakota | 57105 | — |
| Research Site | Chattanooga | Tennessee | 37403 | — |
| Research Site | Austin | Texas | 78701 | — |
| Research Site | Austin | Texas | 78731 | — |
| Research Site | Bedford | Texas | 76022 | — |
| Research Site | Dallas | Texas | 75231 | — |
| Research Site | Dallas | Texas | 75246 | — |
| Research Site | Dallas | Texas | 75390-9032 | — |
| Research Site | Galveston | Texas | 77555 | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | San Antonio | Texas | 78217 | — |
| Research Site | The Woodlands | Texas | 77380 | — |
| Research Site | Ogden | Utah | 84403 | — |
| Research Site | Burlington | Vermont | 05401 | — |
| Research Site | Annandale | Virginia | 22003 | — |
| Research Site | Charlottesville | Virginia | 22908 | — |
| Research Site | Norfolk | Virginia | 23502 | — |
| Research Site | Roanoke | Virginia | 24016 | — |
| Research Site | Winchester | Virginia | 22601 | — |
| Research Site | Woodbridge | Virginia | 22191 | — |
| Research Site | Seattle | Washington | 98104 | — |
| Research Site | Tacoma | Washington | 98405 | — |
| Research Site | Wenatchee | Washington | 98801 | — |
| Research Site | Green Bay | Wisconsin | 54301 | — |
| Research Site | Green Bay | Wisconsin | 54311 | — |
| Research Site | Marshfield | Wisconsin | 54449 | — |
| Research Site | Milwaukee | Wisconsin | 53215 | — |
| Research Site | Milwaukee | Wisconsin | 53226 | — |
| Research Site | Milwaukee | Wisconsin | 53233 | — |
| Research Site | Oshkosh | Wisconsin | 54904 | — |
| Research Site | Sheboygan | Wisconsin | 53081 | — |
| Research Site | Waukesha | Wisconsin | 53188 | — |
| Research Site | Wausau | Wisconsin | 54401 | — |
| Research Site | West Allis | Wisconsin | 53227 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 137 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01493505, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 22, 2017 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01493505 live on ClinicalTrials.gov.