A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
Public ClinicalTrials.gov record NCT01498328. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this research study is to find out whether adding an experimental vaccine called rindopepimut (also known as CDX-110) to the commonly used drug bevacizumab can improve progression free survival (slowing the growth of tumors) of patients with relapsed EGFRvIII positive glioblastoma.
Study identification
- NCT ID
- NCT01498328
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 127 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2011 (Type not available)
- Primary completion
- Apr 2015 (Actual)
- Completion
- May 17, 2016 (Actual)
- Last update posted
- Feb 17, 2020
2011 – 2016
United States locations
- U.S. sites
- 45
- U.S. states
- 23
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| St. Joseph's Hospital and Medical Center / Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| University of Southern California (USC) Norris Comprehensive Cancer Center | Los Angeles | California | 90089 | — |
| UC Irvine Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| Stanford Cancer Institute, Stanford University | Stanford | California | 94305 | — |
| University of Colorado, Denver | Aurora | Colorado | 80045 | — |
| Memorial Cancer Institute | Hollywood | Florida | 33021 | — |
| Orlando Health, Inc. | Orlando | Florida | 32806 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Piedmont Atlanta Hospital | Atlanta | Georgia | 30309 | — |
| Atlanta Cancer Care | Atlanta | Georgia | 30342 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of Chicago | Chicago | Illinois | 60637-1470 | — |
| NorthShore University Health System | Evanston | Illinois | 60201 | — |
| The Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Dana-Farber Cancer Institute and Mass General Hospital Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Sparrow Cancer Center | Lansing | Michigan | 48912 | — |
| John Nasseff Neuroscience Institute, Abbott Northwestern Hospital, 800 e. 28th Str. MR | Minneapolis | Minnesota | 55407 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| New Jersey Neuroscience Institute JFK Medical Center | Edison | New Jersey | 08818 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Dent Neurologic Institute, 3980 Sheridan Dr, 3rd Flr Clinical Rsch | Amherst | New York | 14226 | — |
| The Long Island Brain Tumor Center at Neurology Surgery, P.C. | Commack | New York | 11725 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794-8121 | — |
| The Preston Robert Tisch Brain Tumor Center; Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati Cancer Institute | Cincinnati | Ohio | 45267 | — |
| Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center | Cleveland | Ohio | 44195 | — |
| Legacy Research Institute | Portland | Oregon | 97232 | — |
| Lehigh Valley Hospital-John and Dorothy Morgan Cancer Center | Allentown | Pennsylvania | 18103 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15232 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| Texas Oncology Midtown | Austin | Texas | 78705 | — |
| Baylor Research Institute | Dallas | Texas | 75246 | — |
| UT Health Science Center, Houston Memorial Hermann Hospital, 6400 Fannin Street, #2800 | Houston | Texas | 77030 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84116 | — |
| Swedish Neuroscience Research | Seattle | Washington | 98122 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01498328, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 17, 2020 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01498328 live on ClinicalTrials.gov.