Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis
Public ClinicalTrials.gov record NCT01505088. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Multi-Center, Randomized, Double-Masked, Positive-Controlled Phase 3 Clinical Trial Designed to Evaluate the Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution Compared to Prednisolone Acetate Ophthalmic Suspension (1%) in Patients With Non-Infectious Anterior Segment Uveitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution EGP-437 using the EyeGate® II Drug Delivery System (EGDS) compared to prednisolone acetate ophthalmic suspension (1%) in patients with non-infectious anterior segment uveitis.
Study identification
- NCT ID
- NCT01505088
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 193 participants
Conditions and interventions
Conditions
Interventions
- 40 mg/mL Dexamethasone phosphate ophthalmic solution Drug
- Prednisolone Acetate (1%) Eyedrops Drug
- 100 mM sodium citrate buffer solution Drug
- Placebo Eyedrops Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2011 (Type not available)
- Primary completion
- Feb 2013 (Actual)
- Completion
- Mar 2013 (Actual)
- Last update posted
- Mar 29, 2013
2011 – 2013
United States locations
- U.S. sites
- 39
- U.S. states
- 22
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Department of Ophthalmology at University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Arizona Eye Center | Chandler | Arizona | 85225 | — |
| Associated Retina Consultants | Phoenix | Arizona | 85020 | — |
| Retina-Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Doheny Eye Medical Group | Los Angeles | California | 90033 | — |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | — |
| Colorado Retina Associates | Golden | Colorado | 80401 | — |
| Corneal Consultants of Colorado | Littleton | Colorado | 80120 | — |
| Connecticut Retina Consultants, LLC | Bridgeport | Connecticut | 06606 | — |
| Eye Center of Southern Connecticut | Hamden | Connecticut | 06518 | — |
| Yale Eye Center | New Haven | Connecticut | 06510 | — |
| The Eye Associates of Manatee, LLP | Bradenton | Florida | 34209 | — |
| Levenson Eye Associates | Jacksonville | Florida | 32204 | — |
| Bascom Palmer Eye Institute | Miami | Florida | 33136 | — |
| Logan Ophthalmic Research | Tamarac | Florida | 33321 | — |
| Emory Eye Center | Atlanta | Georgia | 30322 | — |
| Advanced Eye Care | Fort Oglethorpe | Georgia | 30742 | — |
| Illinois Retina Associates | Chicago | Illinois | 60612 | — |
| Raj K. Maturi, M.D. PC | Indianapolis | Indiana | 46290 | — |
| Ellsworth Uveitis and Retina Care | Ellsworth | Maine | 04605 | — |
| Wilmer Eye Institute | Baltimore | Maryland | 21287 | — |
| Massachusetts Eye and Ear Infirmary | Boston | Massachusetts | 02114 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Massachusetts Eye Research and Surgery Institution | Cambridge | Massachusetts | 02142 | — |
| Lifelong Vision Foundation | Chesterfield | Missouri | 63017 | — |
| Tauber Eye Center | Kansas City | Missouri | 64111 | — |
| Comprehensive Eye Care Ltd. | Washington | Missouri | 63090 | — |
| Metropolitan Eye Research and Surgery Institute | Palisades Park | New Jersey | 07650 | — |
| The New York Eye and Ear Infirmary | New York | New York | 10003 | — |
| Charlotte Eye Ear Nose and Throat Associates | Matthews | North Carolina | 28105 | — |
| Casey Eye Institute | Portland | Oregon | 97239 | — |
| Scheie Eye Institute | Philadelphia | Pennsylvania | 19104 | — |
| Mid-Atlantic Retina | Philadelphia | Pennsylvania | 19107 | — |
| Southern College of Optometry | Memphis | Tennessee | 38104 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Houston Eye Associates | Houston | Texas | 77025 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Virginia Eye Consultants | Norfolk | Virginia | 23502 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01505088, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 29, 2013 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01505088 live on ClinicalTrials.gov.