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Completed Phase 4 Interventional Results available

A Long-term Efficacy, Safety, and Tolerability Study of BOTOX® in Patients With Chronic Migraine

ClinicalTrials.gov ID: NCT01516892

Public ClinicalTrials.gov record NCT01516892. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 1:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This open-label study will assess the long-term efficacy, safety, and tolerability of onabotulinumtoxinA administered for prophylaxis of headaches in patients with chronic migraine.

Study identification

NCT ID
NCT01516892
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Allergan
Industry
Enrollment
716 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2011
Primary completion
Oct 31, 2015
Completion
Oct 31, 2015
Last update posted
Jan 5, 2017

2011 – 2015

United States locations

U.S. sites
21
U.S. states
14
U.S. cities
21
Facility City State ZIP Site status
Arizona Neurological Institute Scottsdale Arizona 85255-7450
The Research Center of Southern California, LLC Encinitas California 92024
USC Neurology Los Angeles California 90033
UCSF Headache Center San Francisco California 94133
Neurological Research Institute Santa Monica California 90404
Advanced Neurosciences Research, LLC Fort Collins Colorado 80528
Tampa General Hospital Tampa Florida 33606
Premiere Research Institute at Palm Beach Neurology West Palm Beach Florida 33407
Robbins Headache Clinic Northbrook Illinois 60062
Mid-Atlantic Headache Institute Baltimore Maryland 21208
Kaiser Permanente Research Office/Neurology Department Largo Maryland 20774
Clinvest Research Springfield Missouri 65807-6988
Mercy Health Research St Louis Missouri 63141
Renown Institute for Neurosciences Reno Nevada 89502
Dent Neurologic Institute Amherst New York 14226
Montefiore Medical Center The Bronx New York 10461
Headache Wellness Center Greensboro North Carolina 27405
Ohio Clinical Research Partners, LLC Canton Ohio 44718
Jefferson University Hospitals Philadelphia Pennsylvania 19107
Wesley Headache Clinic Cordova Tennessee 38018
Baylor Research Institute Dallas Texas 75231

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01516892, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 5, 2017 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01516892 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →