Arestin - Use in Subjects With Peri-Implantitis (With Subgingival Microbiological Evaluation)
Public ClinicalTrials.gov record NCT01517334. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multi-Center Phase 3 Trial of Minocycline HCl 1 mg Microspheres for the Use in Subjects With Peri-Implantitis: Clinical and Microbiological Evaluations
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of the study is to evaluate the safety, effectiveness and anti-microbial effects of Arestin (minocycline HCl) 1 mg Microspheres in the treatment of subjects with peri-implantitis, when used in combination with mechanical debridement. The hypothesis of the study is that Arestin in combination with mechanical debridement is more effective in the treatment of peri-implantitis when compared to mechanical debridement alone. The primary efficacy measure will be the reduction of probing depth at Day 180 as measured at qualifying implant sites.
Study identification
- NCT ID
- NCT01517334
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 208 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2012
- Primary completion
- Aug 31, 2014
- Completion
- Oct 31, 2014
- Last update posted
- Aug 25, 2015
2012 – 2014
United States locations
- U.S. sites
- 10
- U.S. states
- 10
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Maryland, School of Dentistry | Baltimore | Maryland | 21201 | — |
| Tufts University School of Dental Medicine | Boston | Massachusetts | 02111 | — |
| University of Michigan - Michigan Center for Oral Health Research | Ann Arbor | Michigan | 48106 | — |
| University of Missouri - Kansas City School of Dentistry Clinical Research Center | Kansas City | Missouri | 64108 | — |
| University of North Carolina at Chapel Hill School of Dentistry | Chapel Hill | North Carolina | 27599 | — |
| University of Pennsylvania School of Dental Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Medical University of South Carolina College of Dental Medicine | Charleston | South Carolina | 29403 | — |
| UTHSC - College of Dentistry | Memphis | Tennessee | 38163 | — |
| Virginia Commonwealth University School of Dentistry | Richmond | Virginia | 98056 | — |
| Marquette University School of Dentstry | Milwaukee | Wisconsin | 53233 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01517334, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 25, 2015 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01517334 live on ClinicalTrials.gov.