ClinicalTrials.gov record
Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer
ClinicalTrials.gov ID: NCT01546987
Public ClinicalTrials.gov record NCT01546987. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) With a GNRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT With a GNRH Agonist and TAK-700 For Men With High Risk Prostate Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Androgens can cause the growth of prostate cancer cells. Drugs, such as steroid 17alpha-monooxygenase TAK-700, when used with other hormone therapy, may lessen the amount of androgens made by the body. Radiation therapy uses high energy x rays to kill tumor cells. This may be an effective treatment for prostate cancer when combined with hormone therapy. Studying quality-of-life in patients having cancer treatment may help identify the intermediate- and long-term effects of treatment on patients with prostate cancer. PURPOSE: This randomized phase III trial is studying the use of hormone therapy, including TAK-700, together with radiation therapy in treating patients with prostate cancer.
Study identification
- NCT ID
- NCT01546987
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 239 participants
Conditions and interventions
Conditions
Interventions
- GnRH agonist Drug
- Anti-androgen Drug
- TAK-700 Drug
- Radiation therapy Radiation
Drug · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2012 (Actual)
- Primary completion
- Nov 1, 2021 (Actual)
- Completion
- Sep 4, 2025 (Actual)
- Last update posted
- Mar 6, 2026
2012 – 2025
United States locations
- U.S. sites
- 165
- U.S. states
- 38
- U.S. cities
- 139
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Kirklin Clinic at Acton Road | Birmingham | Alabama | 35243 | — |
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Arizona Oncology-Deer Valley Center | Phoenix | Arizona | 85027 | — |
| Arizona Oncology Services Foundation | Scottsdale | Arizona | 85260 | — |
| Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn | California | 95603 | — |
| Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park | California | 95682 | — |
| Mercy San Juan Medical Center | Carmichael | California | 95608 | — |
| Veterans Administration Long Beach Medical Center | Long Beach | California | 90822 | — |
| Los Angeles County-USC Medical Center | Los Angeles | California | 90033 | — |
| University of Southern California/Norris Cancer Center | Los Angeles | California | 90033 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Pomona Valley Hospital Medical Center | Pomona | California | 91767 | — |
| Rohnert Park Cancer Center | Rohnert Park | California | 94928 | — |
| Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California | 95661 | — |
| Sutter General Hospital | Sacramento | California | 95816 | — |
| University of California At San Diego | San Diego | California | 92103 | — |
| UCSF-Mount Zion | San Francisco | California | 94115 | — |
| Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | 95051 | — |
| Kaiser Permanente Cancer Treatment Center | South San Francisco | California | 94080 | — |
| Stanford University Hospitals and Clinics | Stanford | California | 94305 | — |
| Sutter Cancer Centers Radiation Oncology Services-Vacaville | Vacaville | California | 95687 | — |
| Sutter Solano Medical Center | Vallejo | California | 94589 | — |
| University of Colorado Cancer Center - Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| Poudre Valley Radiation Oncology | Fort Collins | Colorado | 80528 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| The Hospital of Central Connecticut | New Britain | Connecticut | 06050 | — |
| William Backus Hospital | Norwich | Connecticut | 06360 | — |
| Helen F Graham Cancer Center | Newark | Delaware | 19713 | — |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | — |
| University of Miami Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach | Florida | 33442 | — |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Florida Hospital | Orlando | Florida | 32803 | — |
| Grady Health System | Atlanta | Georgia | 30303 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Emory University/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Atlanta VA Medical Center | Decatur | Georgia | 30033 | — |
| Saint Joseph's-Candler Health System | Savannah | Georgia | 31405 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Idaho Urologic Institute PA | Meridian | Idaho | 83642 | — |
| Weiss Memorial Hospital | Chicago | Illinois | 60640 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Hines Veterans Administration Hospital | Hines | Illinois | 60141 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Radiation Oncology Associates PC | Fort Wayne | Indiana | 46804 | — |
| Parkview Hospital Randallia | Fort Wayne | Indiana | 46805 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Kansas City Cancer Centers-Southwest | Overland Park | Kansas | 66210 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809 | — |
| Touro Infirmary | New Orleans | Louisiana | 70115 | — |
| Ochsner Medical Center Jefferson | New Orleans | Louisiana | 70121 | — |
| Maine Medical Center- Scarborough Campus | Scarborough | Maine | 04074 | — |
| Saint Agnes Hospital | Baltimore | Maryland | 21229 | — |
| Peninsula Regional Medical Center | Salisbury | Maryland | 21801 | — |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Saint Anne's Hospital | Fall River | Massachusetts | 02721 | — |
| Dana-Farber/Brigham and Women's Cancer Center at Milford Regional | Milford | Massachusetts | 01757 | — |
| North Shore Medical Center Cancer Center | Peabody | Massachusetts | 01960 | — |
| Dana-Farber/Brigham and Women's Cancer Center at South Shore | South Weymouth | Massachusetts | 02190 | — |
| Bixby Medical Center | Adrian | Michigan | 49221 | — |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106-0995 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| McLaren-Flint | Flint | Michigan | 48532 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Great Lakes Cancer Institute-Lapeer Campus | Lapeer | Michigan | 48446 | — |
| McLaren Cancer Institute-Owosso | Owosso | Michigan | 48867 | — |
| Northern Michigan Regional Hospital | Petoskey | Michigan | 49770 | — |
| William Beaumont Hospital-Royal Oak | Royal Oak | Michigan | 48073 | — |
| William Beaumont Hospital - Troy | Troy | Michigan | 48098 | — |
| Sanford Clinic North-Bemidgi | Bemidji | Minnesota | 56601 | — |
| Saint Luke's Hospital of Duluth | Duluth | Minnesota | 55805 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Southeast Cancer Center | Cape Girardeau | Missouri | 63703 | — |
| Siteman Cancer Center - Saint Peters | City of Saint Peters | Missouri | 63376 | — |
| Kansas City Cancer Center - South | Kansas City | Missouri | 64131 | — |
| Kansas City Cancer Centers - North | Kansas City | Missouri | 64154 | — |
| Kansas City Cancer Center-Lee's Summit | Lee's Summit | Missouri | 64064 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Siteman Cancer Center-South County | St Louis | Missouri | 63129 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Barnes-Jewish West County Hospital | St Louis | Missouri | 63141 | — |
| Saint John's Mercy Medical Center | St Louis | Missouri | 63141 | — |
| Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| The Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Concord Hospital | Concord | New Hampshire | 03301 | — |
| Exeter Hospital | Exeter | New Hampshire | 03833 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Elliot Hospital | Manchester | New Hampshire | 03103 | — |
| Cooper Hospital University Medical Center | Camden | New Jersey | 08103 | — |
| Saint Peter's University Hospital | New Brunswick | New Jersey | 08901 | — |
| MD Anderson Cancer Center at Cooper-Voorhees | Voorhees Township | New Jersey | 08043 | — |
| Sanford Bismarck Medical Center | Bismarck | North Dakota | 58501 | — |
| Sanford Medical Center-Fargo | Fargo | North Dakota | 58122 | — |
| Summa Akron City Hospital/Cooper Cancer Center | Akron | Ohio | 44304 | — |
| Akron General Medical Center | Akron | Ohio | 44307 | — |
| Summa Barberton Hospital | Barberton | Ohio | 44203 | — |
| Geaugra Hospital | Chardon | Ohio | 44024 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| Mercy Cancer Center-Elyria | Elyria | Ohio | 44035 | — |
| Summa Health Center at Lake Medina | Medina | Ohio | 44256 | — |
| Lake University Ireland Cancer Center | Mentor | Ohio | 44060 | — |
| Southwest General Health Center Ireland Cancer Center | Middleburg Heights | Ohio | 44130 | — |
| UHHS-Chagrin Highlands Medical Center | Orange | Ohio | 44122 | — |
| Robinson Radiation Oncology | Ravenna | Ohio | 44266 | — |
| Ireland Cancer Center at Firelands Regional Medical Center | Sandusky | Ohio | 44870 | — |
| Flower Hospital | Sylvania | Ohio | 43560 | — |
| UHHS-Westlake Medical Center | Westlake | Ohio | 44145 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Natalie Warren Bryant Cancer Center at Saint Francis | Tulsa | Oklahoma | 74136 | — |
| Rogue Valley Medical Center | Medford | Oregon | 97504 | — |
| Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | 19026 | — |
| The Regional Cancer Center | Erie | Pennsylvania | 16505 | — |
| Adams Cancer Center | Gettysburg | Pennsylvania | 17325 | — |
| Cherry Tree Cancer Center | Hanover | Pennsylvania | 17331 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Lankenau Hospital | Wynnewood | Pennsylvania | 19096 | — |
| WellSpan Health-York Hospital | York | Pennsylvania | 17405 | — |
| Gibbs Cancer Center-Pelham | Greer | South Carolina | 29651 | — |
| Spartanburg Regional Medical Center | Spartanburg | South Carolina | 29303 | — |
| Lexington Medical Center | West Columbia | South Carolina | 29169 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Texas Oncology PA - Bedford | Bedford | Texas | 76022 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| The Klabzuba Cancer Center | Fort Worth | Texas | 76104 | — |
| University of Texas Medical Branch at Galveston | Galveston | Texas | 77555-0565 | — |
| Memorial Hermann Memorial City Medical Center | Houston | Texas | 77024 | — |
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
| UTMB Cancer Center at Victory Lakes | League City | Texas | 77573 | — |
| Texas Cancer Center-Sherman | Sherman | Texas | 75090 | — |
| Texas Oncology Cancer Center Sugar Land | Sugar Land | Texas | 77479 | — |
| Intermountain Medical Center | Murray | Utah | 84157 | — |
| Utah Cancer Specialists-Salt Lake City | Salt Lake City | Utah | 84106 | — |
| Dixie Medical Center Regional Cancer Center | St. George | Utah | 84770 | — |
| Sentara Cancer Institute at Sentara CarePlex Hospital | Hampton | Virginia | 23666 | — |
| Sentara Hospitals | Norfolk | Virginia | 23507 | — |
| Oncology and Hematology Associates of Southwest Virginia | Roanoke | Virginia | 24014 | — |
| Sentara Virginia Beach General Hospital | Virginia Beach | Virginia | 23454 | — |
| Saint Francis Hospital | Federal Way | Washington | 98003 | — |
| Virginia Mason CCOP | Seattle | Washington | 98101 | — |
| Appleton Medical Center | Appleton | Wisconsin | 54911 | — |
| Saint Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
| Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| Gundersen Lutheran | La Crosse | Wisconsin | 54601 | — |
| Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Columbia Saint Mary's Hospital - Ozaukee | Mequon | Wisconsin | 53097 | — |
| Columbia Saint Mary's Water Tower Medical Commons | Milwaukee | Wisconsin | 53211 | — |
| Froedtert and the Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Clement J. Zablocki VA Medical Center | Milwaukee | Wisconsin | 53295 | — |
| Wheaton Franciscan Cancer Care - All Saints | Racine | Wisconsin | 53405 | — |
| Door County Cancer Center | Sturgeon Bay | Wisconsin | 54235-1495 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01546987, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 6, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01546987 live on ClinicalTrials.gov.