Hepatic Impairment Study For Crizotinib In Advanced Cancer Patients
Public ClinicalTrials.gov record NCT01576406. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase I Study To Evaluate The Effect Of Hepatic Impairment On The Pharmacokinetics And Safety Of Crizotinib In Advanced Cancer Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to evaluate the potential effect of hepatic impairment on the pharmacokinetics and safety of crizotinib in advanced cancer patients. Advanced cancer patients with mild, moderate or severe liver dysfunction as well as patients with normal liver function will be enrolled in this study.
Study identification
- NCT ID
- NCT01576406
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 88 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2012 (Actual)
- Primary completion
- Jun 2016 (Actual)
- Completion
- Jun 2016 (Actual)
- Last update posted
- Oct 25, 2018
2012 – 2016
United States locations
- U.S. sites
- 20
- U.S. states
- 5
- U.S. cities
- 5
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Keck Hospital of USC | Los Angeles | California | 90033 | — |
| LAC&USC Medical Center | Los Angeles | California | 90033 | — |
| USC/Norris Comprehensive Cancer Center / Investigational Drug Services | Los Angeles | California | 90033 | — |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Anschutz Cancer Pavilion, Room 2224, c/o Melinda Friesleben, Pharm D | Aurora | Colorado | 80045 | — |
| University of Colorado Denver - Clinical Translational Research Center | Aurora | Colorado | 80045 | — |
| University of Colorado Denver, Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| University of Colorado Denver, Anschutz Inpatient Pavillion | Aurora | Colorado | 80045 | — |
| Emory University Hospital Midtown Laboratory | Atlanta | Georgia | 30308 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Investigational Drug Service: The Emory Clinic Bldg A | Atlanta | Georgia | 30322 | — |
| The Emory Clinic | Atlanta | Georgia | 30322 | — |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| University Hospital East | Columbus | Ohio | 43205 | — |
| Investigational Drug Services | Columbus | Ohio | 43210 | — |
| James Cancer Hospital | Columbus | Ohio | 43210 | — |
| The Ohio State University, Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Martha Morehouse Medical Plaza | Columbus | Ohio | 43221 | — |
| Cancer Therapy & Research Center at UTHSCSA | San Antonio | Texas | 78229 | — |
| Medical Arts and Research Center-MARC | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01576406, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 25, 2018 · Synced Oct 2, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01576406 live on ClinicalTrials.gov.