Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study)
Public ClinicalTrials.gov record NCT01583218. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
(Apex) Multicenter, Randomized, Active-Controlled Efficacy And Safety Study Comparing Extended Duration Betrixaban With Standard Of Care Enoxaparin For The Prevention Of Venous Thromboembolism In Acute Medically Ill Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate whether extended prophylaxis with oral betrixaban can prevent blood clots in the leg and lung that sometime occur in patients hospitalized for an acute medical illness and to compare these results with standard of care enoxaparin. The safety of betrixaban will also be studied.
Study identification
- NCT ID
- NCT01583218
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 7,513 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 2012 (Type not available)
- Primary completion
- Dec 2015 (Actual)
- Completion
- Jan 2016 (Actual)
- Last update posted
- Aug 7, 2023
2012 – 2016
United States locations
- U.S. sites
- 75
- U.S. states
- 29
- U.S. cities
- 72
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | 35294 | — |
| Not listed | Bakersfield | California | 93308 | — |
| Not listed | Fresno | California | 93701 | — |
| Not listed | La Mesa | California | 91942 | — |
| Not listed | Long Beach | California | 90822 | — |
| Not listed | Los Angeles | California | 90073 | — |
| Not listed | Modesto | California | 95350 | — |
| Not listed | San Diego | California | 92120 | — |
| Not listed | Stanford | California | 94305 | — |
| Not listed | Torrance | California | 90509 | — |
| Not listed | Englewood | Colorado | 80113 | — |
| Not listed | Bay Pines | Florida | 33744 | — |
| Not listed | Clearwater | Florida | 33756 | — |
| Not listed | Jacksonville | Florida | 32216 | — |
| Not listed | Miami | Florida | 33143 | — |
| Not listed | Pensacola | Florida | 32504 | — |
| Not listed | Sarasota | Florida | 34232 | — |
| Not listed | Vero Beach | Florida | 32960 | — |
| Not listed | Columbus | Georgia | 31904 | — |
| Not listed | Decatur | Georgia | 30030 | — |
| Not listed | Chicago | Illinois | 60611 | — |
| Not listed | Oak Park | Illinois | 60302 | — |
| Not listed | Carmel | Indiana | 46032 | — |
| Not listed | Davenport | Iowa | 52803 | — |
| Not listed | Windsor Heights | Iowa | 50324 | — |
| Not listed | Topeka | Kansas | 66604 | — |
| Not listed | Hazard | Kentucky | 41701 | — |
| Not listed | Annapolis | Maryland | 21401 | — |
| Not listed | Baltimore | Maryland | 21287 | — |
| Not listed | Detroit | Michigan | 48202 | — |
| Not listed | Grand Blanc | Michigan | 48439 | — |
| Not listed | Royal Oak | Michigan | 48073 | — |
| Not listed | Troy | Michigan | 48085 | — |
| Not listed | Duluth | Minnesota | 55805 | — |
| Not listed | Picayune | Mississippi | 39466 | — |
| Not listed | Kansas City | Missouri | 64111 | — |
| Not listed | St Louis | Missouri | 63110 | — |
| Not listed | Butte | Montana | 59701 | — |
| Not listed | Omaha | Nebraska | 68131 | — |
| Not listed | Las Vegas | Nevada | 89109 | — |
| Not listed | Reno | Nevada | 89502 | — |
| Not listed | Atlantic City | New Jersey | 08401 | — |
| Not listed | Pomona | New Jersey | 08240 | — |
| Not listed | Somerville | New Jersey | 08876 | — |
| Not listed | Summit | New Jersey | 07901 | — |
| Not listed | Buffalo | New York | 14209 | — |
| Not listed | Manhasset | New York | 11030 | — |
| Not listed | Staten Island | New York | 10305 | — |
| Not listed | Valhalla | New York | 10595 | — |
| Not listed | Durham | North Carolina | 27710 | — |
| Not listed | Cincinnati | Ohio | 45267 | — |
| Not listed | Cleveland | Ohio | 44106-5072 | — |
| Not listed | Columbus | Ohio | 43210 | — |
| Not listed | Camp Hill | Pennsylvania | 17011 | — |
| Not listed | Philadelphia | Pennsylvania | 19107 | — |
| Not listed | Charleston | South Carolina | 29425 | — |
| Not listed | Orangeburg | South Carolina | 29118 | — |
| Not listed | Austin | Texas | 78705 | — |
| Not listed | Austin | Texas | 78752 | — |
| Not listed | Bellaire | Texas | 77401 | — |
| Not listed | Corsicana | Texas | 75110 | — |
| Not listed | Dallas | Texas | 75216 | — |
| Not listed | Fort Worth | Texas | 76104 | — |
| Not listed | Houston | Texas | 77024 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | McAllen | Texas | 78501 | — |
| Not listed | Mission | Texas | 78572 | — |
| Not listed | San Antonio | Texas | 78205 | — |
| Not listed | San Antonio | Texas | 78258 | — |
| Not listed | Victoria | Texas | 77901 | — |
| Not listed | Colchester | Vermont | 05401 | — |
| Not listed | Charlottesville | Virginia | 22908 | — |
| Not listed | Richmond | Virginia | 23249 | — |
| Not listed | Everett | Washington | 98201 | — |
| Not listed | Huntington | West Virginia | 25701 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 387 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01583218, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 7, 2023 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01583218 live on ClinicalTrials.gov.