Study of Dasatinib vs Imatinib in Patients With Chronic Myeloid Leukemia (CML) Who Did Not Have Favorable Response to Imatinib
Public ClinicalTrials.gov record NCT01593254. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open Label, Randomized (2:1) Phase IIb Study of Dasatinib Versus Imatinib in Patients With Chronic Phase Chronic Myeloid Leukemia Who Have Not Achieved an Optimal Response to 3 Months of Therapy With 400 mg Imatinib
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to test the hypothesis that patients with CML who have not achieved optimal response after 3 months of treatment with imatinib will have a better response by switching to dasatinib compared to staying on their original imatinib regimen.
Study identification
- NCT ID
- NCT01593254
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 262 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 11, 2012
- Primary completion
- Nov 7, 2017
- Completion
- Apr 11, 2022
- Last update posted
- Jun 21, 2023
2012 – 2022
United States locations
- U.S. sites
- 21
- U.S. states
- 12
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0004 | Anaheim | California | 92801 | — |
| Local Institution - 0006 | Fontana | California | 92335 | — |
| University Of Southern California University Hospital | Los Angeles | California | 90033 | — |
| Local Institution - 0110 | Roseville | California | 95661 | — |
| Local Institution - 0112 | San Jose | California | 95119 | — |
| Local Institution - 0009 | Vallejo | California | 94589-2441 | — |
| Local Institution - 0078 | Whittier | California | 90603 | — |
| Local Institution - 0089 | Southington | Connecticut | 06489 | — |
| Northwestern University | Evanston | Illinois | 60208 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Northern Indiana Cancer Research Consortium | Crown Point | Indiana | 46307 | — |
| Franciscan St. Francis Health | Indianapolis | Indiana | 46237 | — |
| University Of Iowa | Iowa City | Iowa | 52242 | — |
| Local Institution - 0010 | Rochester | Minnesota | 55905 | — |
| Local Institution - 0002 | Cincinnati | Ohio | 45242 | — |
| Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| Local Institution - 0001 | Nashville | Tennessee | 37203-1625 | — |
| Michael E Debakey VAMC | Houston | Texas | 77030 | — |
| Institute of Oncology Hematology Biomedical Research | Laredo | Texas | 78041 | — |
| Edwards Comprehensive Cancer Center | Huntington | West Virginia | 25701 | — |
| Local Institution - 0005 | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01593254, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 21, 2023 · Synced Sep 24, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01593254 live on ClinicalTrials.gov.