ClinicalTrials.gov record
Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)
ClinicalTrials.gov ID: NCT01601704
Public ClinicalTrials.gov record NCT01601704. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 8, 2026, 12:29 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Assessing the Occurrence of Major Adverse Cardiovascular Events (MACE) in Overweight and Obese Subjects With Cardiovascular Risk Factors Receiving Naltrexone SR/Bupropion SR
Study identification
- NCT ID
- NCT01601704
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Orexigen Therapeutics, Inc
- Industry
- Enrollment
- 8,910 participants
Conditions and interventions
Conditions
Interventions
- NB32 Drug
- PBO Drug
- Weight Management Program Behavioral
Drug · Behavioral
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2012
- Primary completion
- Jul 31, 2015
- Completion
- Jul 31, 2015
- Last update posted
- Feb 26, 2017
2012 – 2015
United States locations
- U.S. sites
- 224
- U.S. states
- 44
- U.S. cities
- 224
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Dothan | Alabama | — | — |
| Not listed | Mobile | Alabama | — | — |
| Not listed | Scottsboro | Alabama | — | — |
| Not listed | Chandler | Arizona | — | — |
| Not listed | Mesa | Arizona | — | — |
| Not listed | Peoria | Arizona | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Scottsdale | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Tuscson | Arizona | — | — |
| Not listed | Little Rock | Arkansas | — | — |
| Not listed | Anaheim | California | — | — |
| Not listed | Carmichael | California | — | — |
| Not listed | Escondido | California | — | — |
| Not listed | Fresno | California | — | — |
| Not listed | Harbor City | California | — | — |
| Not listed | Huntington Beach | California | — | — |
| Not listed | La Jolla | California | — | — |
| Not listed | Lomita | California | — | — |
| Not listed | Los Angeles | California | — | — |
| Not listed | Paramount | California | — | — |
| Not listed | Pasadena | California | — | — |
| Not listed | Riverside | California | — | — |
| Not listed | Sacramento | California | — | — |
| Not listed | Santa Rosa | California | — | — |
| Not listed | Spring Valley | California | — | — |
| Not listed | Thousand Oaks | California | — | — |
| Not listed | Torrance | California | — | — |
| Not listed | West Hills | California | — | — |
| Not listed | Colorado Springs | Colorado | — | — |
| Not listed | Denver | Colorado | — | — |
| Not listed | Golden | Colorado | — | — |
| Not listed | Wheat Ridge | Colorado | — | — |
| Not listed | Norwalk | Connecticut | — | — |
| Not listed | Stamford | Connecticut | — | — |
| Not listed | Wilmington | Delaware | — | — |
| Not listed | Washington D.C. | District of Columbia | — | — |
| Not listed | Boynton Beach | Florida | — | — |
| Not listed | Brooksville | Florida | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | DeLand | Florida | — | — |
| Not listed | Delray Beach | Florida | — | — |
| Not listed | Gainesville | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Jacksonville Beach | Florida | — | — |
| Not listed | Melbourne | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | New Port Richey | Florida | — | — |
| Not listed | New Smyrna Beach | Florida | — | — |
| Not listed | Oakland Park | Florida | — | — |
| Not listed | Orlando | Florida | — | — |
| Not listed | Palm Harbor | Florida | — | — |
| Not listed | Pembroke Pines | Florida | — | — |
| Not listed | Pensacola | Florida | — | — |
| Not listed | Pinellas Park | Florida | — | — |
| Not listed | St. Petersburg | Florida | — | — |
| Not listed | Vero Beach | Florida | — | — |
| Not listed | Wellington | Florida | — | — |
| Not listed | Winter Haven | Florida | — | — |
| Not listed | Atlanta | Georgia | — | — |
| Not listed | Austell | Georgia | — | — |
| Not listed | Columbus | Georgia | — | — |
| Not listed | Lawrenceville | Georgia | — | — |
| Not listed | Riverdale | Georgia | — | — |
| Not listed | Savannah | Georgia | — | — |
| Not listed | Stockbridge | Georgia | — | — |
| Not listed | Honolulu | Hawaii | — | — |
| Not listed | Meridian | Idaho | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Gurnee | Illinois | — | — |
| Not listed | Melrose Park | Illinois | — | — |
| Not listed | Bloomington | Indiana | — | — |
| Not listed | Brownsburg | Indiana | — | — |
| Not listed | Elwood | Indiana | — | — |
| Not listed | Evansville | Indiana | — | — |
| Not listed | Hammond | Indiana | — | — |
| Not listed | South Bend | Indiana | — | — |
| Not listed | Valparaiso | Indiana | — | — |
| Not listed | Ames | Iowa | — | — |
| Not listed | Council Bluffs | Iowa | — | — |
| Not listed | Des Moines | Iowa | — | — |
| Not listed | West Des Moines | Iowa | — | — |
| Not listed | Overland Park | Kansas | — | — |
| Not listed | Wichita | Kansas | — | — |
| Not listed | Crestview Hills | Kentucky | — | — |
| Not listed | Louisville | Kentucky | — | — |
| Not listed | Mount Sterling | Kentucky | — | — |
| Not listed | Alexandria | Louisiana | — | — |
| Not listed | Baton Rouge | Louisiana | — | — |
| Not listed | Monroe | Louisiana | — | — |
| Not listed | Natchitoches | Louisiana | — | — |
| Not listed | Auburn | Maine | — | — |
| Not listed | Bangor | Maine | — | — |
| Not listed | Baltimore | Maryland | — | — |
| Not listed | Columbia | Maryland | — | — |
| Not listed | Elkridge | Maryland | — | — |
| Not listed | Lutherville | Maryland | — | — |
| Not listed | Salisbury | Maryland | — | — |
| Not listed | Boston | Massachusetts | — | — |
| Not listed | Brockton | Massachusetts | — | — |
| Not listed | Fall River | Massachusetts | — | — |
| Not listed | Haverhill | Massachusetts | — | — |
| Not listed | Methuen | Massachusetts | — | — |
| Not listed | Bingham Farms | Michigan | — | — |
| Not listed | Dearbon | Michigan | — | — |
| Not listed | Kalamazoo | Michigan | — | — |
| Not listed | Midland | Michigan | — | — |
| Not listed | Saginaw | Michigan | — | — |
| Not listed | Southfield | Michigan | — | — |
| Not listed | Stevensville | Michigan | — | — |
| Not listed | Edina | Minnesota | — | — |
| Not listed | Rochester | Minnesota | — | — |
| Not listed | Jackson | Mississippi | — | — |
| Not listed | Olive Branch | Mississippi | — | — |
| Not listed | Tupelo | Mississippi | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | Butte | Montana | — | — |
| Not listed | Missoula | Montana | — | — |
| Not listed | Fremont | Nebraska | — | — |
| Not listed | Grand Island | Nebraska | — | — |
| Not listed | Omaha | Nebraska | — | — |
| Not listed | Henderson | Nevada | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Reno | Nevada | — | — |
| Not listed | Sparks | Nevada | — | — |
| Not listed | Belvidere | New Jersey | — | — |
| Not listed | Edison | New Jersey | — | — |
| Not listed | Elizabeth | New Jersey | — | — |
| Not listed | Elmer | New Jersey | — | — |
| Not listed | Linden | New Jersey | — | — |
| Not listed | Ridgewood | New Jersey | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Endwell | New York | — | — |
| Not listed | New Hyde Park | New York | — | — |
| Not listed | New York | New York | — | — |
| Not listed | Staten Island | New York | — | — |
| Not listed | Syracuse | New York | — | — |
| Not listed | The Bronx | New York | — | — |
| Not listed | Williamsville | New York | — | — |
| Not listed | Cary | North Carolina | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Durham | North Carolina | — | — |
| Not listed | Elizabeth City | North Carolina | — | — |
| Not listed | Greensboro | North Carolina | — | — |
| Not listed | Greenville | North Carolina | — | — |
| Not listed | Hickory | North Carolina | — | — |
| Not listed | Morganton | North Carolina | — | — |
| Not listed | Raleigh | North Carolina | — | — |
| Not listed | Salisbury | North Carolina | — | — |
| Not listed | Wilmington | North Carolina | — | — |
| Not listed | Winston-Salem | North Carolina | — | — |
| Not listed | Akron | Ohio | — | — |
| Not listed | Beachwood | Ohio | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Cleveland | Ohio | — | — |
| Not listed | Columbus | Ohio | — | — |
| Not listed | Delaware | Ohio | — | — |
| Not listed | Kettering | Ohio | — | — |
| Not listed | Marion | Ohio | — | — |
| Not listed | Mentor | Ohio | — | — |
| Not listed | Willoughby Hills | Ohio | — | — |
| Not listed | Oklahoma City | Oklahoma | — | — |
| Not listed | Medford | Oregon | — | — |
| Not listed | Portland | Oregon | — | — |
| Not listed | Altoona | Pennsylvania | — | — |
| Not listed | Bensalem | Pennsylvania | — | — |
| Not listed | Danville | Pennsylvania | — | — |
| Not listed | Duncansville | Pennsylvania | — | — |
| Not listed | Ephrata | Pennsylvania | — | — |
| Not listed | Jersey Shore | Pennsylvania | — | — |
| Not listed | Lancaster | Pennsylvania | — | — |
| Not listed | Lansdale | Pennsylvania | — | — |
| Not listed | Norristown | Pennsylvania | — | — |
| Not listed | Scottdale | Pennsylvania | — | — |
| Not listed | Sellersville | Pennsylvania | — | — |
| Not listed | State College | Pennsylvania | — | — |
| Not listed | West Reading | Pennsylvania | — | — |
| Not listed | Wilkes-Barre | Pennsylvania | — | — |
| Not listed | Anderson | South Carolina | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Columbia | South Carolina | — | — |
| Not listed | Greenville | South Carolina | — | — |
| Not listed | Greer | South Carolina | — | — |
| Not listed | Hodges | South Carolina | — | — |
| Not listed | Laurens | South Carolina | — | — |
| Not listed | Mt. Pleasant | South Carolina | — | — |
| Not listed | Rapid City | South Dakota | — | — |
| Not listed | Bristol | Tennessee | — | — |
| Not listed | Chattanooga | Tennessee | — | — |
| Not listed | Germantown | Tennessee | — | — |
| Not listed | Jackson | Tennessee | — | — |
| Not listed | Kingsport | Tennessee | — | — |
| Not listed | Knoxville | Tennessee | — | — |
| Not listed | Memphis | Tennessee | — | — |
| Not listed | Beaumont | Texas | — | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Hurst | Texas | — | — |
| Not listed | Lake Jackson | Texas | — | — |
| Not listed | McKinney | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Schertz | Texas | — | — |
| Not listed | Tomball | Texas | — | — |
| Not listed | Waco | Texas | — | — |
| Not listed | Bountiful | Utah | — | — |
| Not listed | Draper | Utah | — | — |
| Not listed | Murray | Utah | — | — |
| Not listed | Ogden | Utah | — | — |
| Not listed | Orem | Utah | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | West Jordan | Utah | — | — |
| Not listed | Alexandria | Virginia | — | — |
| Not listed | Norfolk | Virginia | — | — |
| Not listed | Richmond | Virginia | — | — |
| Not listed | Winchester | Virginia | — | — |
| Not listed | Seattle | Washington | — | — |
| Not listed | Spokane | Washington | — | — |
| Not listed | Tacoma | Washington | — | — |
| Not listed | Walla Walla | Washington | — | — |
| Not listed | Green Bay | Wisconsin | — | — |
| Not listed | Kenosha | Wisconsin | — | — |
| Not listed | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01601704, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 26, 2017 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01601704 live on ClinicalTrials.gov.