ClinicalTrials.gov record
Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)
ClinicalTrials.gov ID: NCT01601704
Public ClinicalTrials.gov record NCT01601704. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Assessing the Occurrence of Major Adverse Cardiovascular Events (MACE) in Overweight and Obese Subjects With Cardiovascular Risk Factors Receiving Naltrexone SR/Bupropion SR
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the effects of NB relative to placebo on major adverse cardiovascular events (MACE) such as cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in overweight and obese subjects who are at a higher risk of having these events because they have diabetes and/or other cardiovascular risk factors.
Study identification
- NCT ID
- NCT01601704
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 8,910 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 45 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2012 (Type not available)
- Primary completion
- Aug 2015 (Actual)
- Completion
- Aug 2015 (Actual)
- Last update posted
- Feb 27, 2017
2012 – 2015
United States locations
- U.S. sites
- 224
- U.S. states
- 44
- U.S. cities
- 224
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Dothan | Alabama | — | — |
| Not listed | Mobile | Alabama | — | — |
| Not listed | Scottsboro | Alabama | — | — |
| Not listed | Chandler | Arizona | — | — |
| Not listed | Mesa | Arizona | — | — |
| Not listed | Peoria | Arizona | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Scottsdale | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Tuscson | Arizona | — | — |
| Not listed | Little Rock | Arkansas | — | — |
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| Not listed | Fresno | California | — | — |
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| Not listed | Denver | Colorado | — | — |
| Not listed | Golden | Colorado | — | — |
| Not listed | Wheat Ridge | Colorado | — | — |
| Not listed | Norwalk | Connecticut | — | — |
| Not listed | Stamford | Connecticut | — | — |
| Not listed | Wilmington | Delaware | — | — |
| Not listed | Washington D.C. | District of Columbia | — | — |
| Not listed | Boynton Beach | Florida | — | — |
| Not listed | Brooksville | Florida | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | DeLand | Florida | — | — |
| Not listed | Delray Beach | Florida | — | — |
| Not listed | Gainesville | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Jacksonville Beach | Florida | — | — |
| Not listed | Melbourne | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | New Port Richey | Florida | — | — |
| Not listed | New Smyrna Beach | Florida | — | — |
| Not listed | Oakland Park | Florida | — | — |
| Not listed | Orlando | Florida | — | — |
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| Not listed | Pembroke Pines | Florida | — | — |
| Not listed | Pensacola | Florida | — | — |
| Not listed | Pinellas Park | Florida | — | — |
| Not listed | St. Petersburg | Florida | — | — |
| Not listed | Vero Beach | Florida | — | — |
| Not listed | Wellington | Florida | — | — |
| Not listed | Winter Haven | Florida | — | — |
| Not listed | Atlanta | Georgia | — | — |
| Not listed | Austell | Georgia | — | — |
| Not listed | Columbus | Georgia | — | — |
| Not listed | Lawrenceville | Georgia | — | — |
| Not listed | Riverdale | Georgia | — | — |
| Not listed | Savannah | Georgia | — | — |
| Not listed | Stockbridge | Georgia | — | — |
| Not listed | Honolulu | Hawaii | — | — |
| Not listed | Meridian | Idaho | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Gurnee | Illinois | — | — |
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| Not listed | Hammond | Indiana | — | — |
| Not listed | South Bend | Indiana | — | — |
| Not listed | Valparaiso | Indiana | — | — |
| Not listed | Ames | Iowa | — | — |
| Not listed | Council Bluffs | Iowa | — | — |
| Not listed | Des Moines | Iowa | — | — |
| Not listed | West Des Moines | Iowa | — | — |
| Not listed | Overland Park | Kansas | — | — |
| Not listed | Wichita | Kansas | — | — |
| Not listed | Crestview Hills | Kentucky | — | — |
| Not listed | Louisville | Kentucky | — | — |
| Not listed | Mount Sterling | Kentucky | — | — |
| Not listed | Alexandria | Louisiana | — | — |
| Not listed | Baton Rouge | Louisiana | — | — |
| Not listed | Monroe | Louisiana | — | — |
| Not listed | Natchitoches | Louisiana | — | — |
| Not listed | Auburn | Maine | — | — |
| Not listed | Bangor | Maine | — | — |
| Not listed | Baltimore | Maryland | — | — |
| Not listed | Columbia | Maryland | — | — |
| Not listed | Elkridge | Maryland | — | — |
| Not listed | Lutherville | Maryland | — | — |
| Not listed | Salisbury | Maryland | — | — |
| Not listed | Boston | Massachusetts | — | — |
| Not listed | Brockton | Massachusetts | — | — |
| Not listed | Fall River | Massachusetts | — | — |
| Not listed | Haverhill | Massachusetts | — | — |
| Not listed | Methuen | Massachusetts | — | — |
| Not listed | Bingham Farms | Michigan | — | — |
| Not listed | Dearbon | Michigan | — | — |
| Not listed | Kalamazoo | Michigan | — | — |
| Not listed | Midland | Michigan | — | — |
| Not listed | Saginaw | Michigan | — | — |
| Not listed | Southfield | Michigan | — | — |
| Not listed | Stevensville | Michigan | — | — |
| Not listed | Edina | Minnesota | — | — |
| Not listed | Rochester | Minnesota | — | — |
| Not listed | Jackson | Mississippi | — | — |
| Not listed | Olive Branch | Mississippi | — | — |
| Not listed | Tupelo | Mississippi | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | Butte | Montana | — | — |
| Not listed | Missoula | Montana | — | — |
| Not listed | Fremont | Nebraska | — | — |
| Not listed | Grand Island | Nebraska | — | — |
| Not listed | Omaha | Nebraska | — | — |
| Not listed | Henderson | Nevada | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Reno | Nevada | — | — |
| Not listed | Sparks | Nevada | — | — |
| Not listed | Belvidere | New Jersey | — | — |
| Not listed | Edison | New Jersey | — | — |
| Not listed | Elizabeth | New Jersey | — | — |
| Not listed | Elmer | New Jersey | — | — |
| Not listed | Linden | New Jersey | — | — |
| Not listed | Ridgewood | New Jersey | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Endwell | New York | — | — |
| Not listed | New Hyde Park | New York | — | — |
| Not listed | New York | New York | — | — |
| Not listed | Staten Island | New York | — | — |
| Not listed | Syracuse | New York | — | — |
| Not listed | The Bronx | New York | — | — |
| Not listed | Williamsville | New York | — | — |
| Not listed | Cary | North Carolina | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Durham | North Carolina | — | — |
| Not listed | Elizabeth City | North Carolina | — | — |
| Not listed | Greensboro | North Carolina | — | — |
| Not listed | Greenville | North Carolina | — | — |
| Not listed | Hickory | North Carolina | — | — |
| Not listed | Morganton | North Carolina | — | — |
| Not listed | Raleigh | North Carolina | — | — |
| Not listed | Salisbury | North Carolina | — | — |
| Not listed | Wilmington | North Carolina | — | — |
| Not listed | Winston-Salem | North Carolina | — | — |
| Not listed | Akron | Ohio | — | — |
| Not listed | Beachwood | Ohio | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Cleveland | Ohio | — | — |
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| Not listed | Portland | Oregon | — | — |
| Not listed | Altoona | Pennsylvania | — | — |
| Not listed | Bensalem | Pennsylvania | — | — |
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| Not listed | Sellersville | Pennsylvania | — | — |
| Not listed | State College | Pennsylvania | — | — |
| Not listed | West Reading | Pennsylvania | — | — |
| Not listed | Wilkes-Barre | Pennsylvania | — | — |
| Not listed | Anderson | South Carolina | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Columbia | South Carolina | — | — |
| Not listed | Greenville | South Carolina | — | — |
| Not listed | Greer | South Carolina | — | — |
| Not listed | Hodges | South Carolina | — | — |
| Not listed | Laurens | South Carolina | — | — |
| Not listed | Mt. Pleasant | South Carolina | — | — |
| Not listed | Rapid City | South Dakota | — | — |
| Not listed | Bristol | Tennessee | — | — |
| Not listed | Chattanooga | Tennessee | — | — |
| Not listed | Germantown | Tennessee | — | — |
| Not listed | Jackson | Tennessee | — | — |
| Not listed | Kingsport | Tennessee | — | — |
| Not listed | Knoxville | Tennessee | — | — |
| Not listed | Memphis | Tennessee | — | — |
| Not listed | Beaumont | Texas | — | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Hurst | Texas | — | — |
| Not listed | Lake Jackson | Texas | — | — |
| Not listed | McKinney | Texas | — | — |
| Not listed | San Antonio | Texas | — | — |
| Not listed | Schertz | Texas | — | — |
| Not listed | Tomball | Texas | — | — |
| Not listed | Waco | Texas | — | — |
| Not listed | Bountiful | Utah | — | — |
| Not listed | Draper | Utah | — | — |
| Not listed | Murray | Utah | — | — |
| Not listed | Ogden | Utah | — | — |
| Not listed | Orem | Utah | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | West Jordan | Utah | — | — |
| Not listed | Alexandria | Virginia | — | — |
| Not listed | Norfolk | Virginia | — | — |
| Not listed | Richmond | Virginia | — | — |
| Not listed | Winchester | Virginia | — | — |
| Not listed | Seattle | Washington | — | — |
| Not listed | Spokane | Washington | — | — |
| Not listed | Tacoma | Washington | — | — |
| Not listed | Walla Walla | Washington | — | — |
| Not listed | Green Bay | Wisconsin | — | — |
| Not listed | Kenosha | Wisconsin | — | — |
| Not listed | Madison | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01601704, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 27, 2017 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01601704 live on ClinicalTrials.gov.