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Terminated Phase 1Phase 2 Interventional Results available

A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

ClinicalTrials.gov ID: NCT01602315

Public ClinicalTrials.gov record NCT01602315. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 4:41 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase Ib Dose Escalation/Randomized Phase II, Multicenter, Open-label Study of BYL719 in Combination With Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Study identification

NCT ID
NCT01602315
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
179 participants

Conditions and interventions

Interventions

  • BYL719 as film-coated (FC) whole tablets Drug
  • BYL719 as dispersible tablets (DT) Drug
  • cetuximab Biological
  • BYL719 drink suspension Drug

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 11, 2012
Primary completion
Sep 15, 2016
Completion
Sep 15, 2016
Last update posted
Dec 28, 2020

2012 – 2016

United States locations

U.S. sites
14
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
Novartis Investigative Site Sacramento California 95817
Novartis Investigative Site San Francisco California 94101
Novartis Investigative Site Aurora Colorado 80045
Novartis Investigative Site Jacksonville Florida 32224
Novartis Investigative Site Orlando Florida 32806
Novartis Investigative Site Atlanta Georgia 30322
Novartis Investigative Site Boston Massachusetts 02114
Novartis Investigative Site St Louis Missouri 63110
Novartis Investigative Site New York New York 10017
Novartis Investigative Site New York New York 10029
Novartis Investigative Site Philadelphia Pennsylvania 19104
Novartis Investigative Site Charleston South Carolina 29425
Novartis Investigative Site Nashville Tennessee 37232
Novartis Investigative Site Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01602315, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 28, 2020 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01602315 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →