A Study of CNTO 136 (Sirukumab), Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Disease-Modifying Antirheumatic Drug (DMARD) Therapy (SIRROUND-D)
Public ClinicalTrials.gov record NCT01604343. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Subjects With Active Rheumatoid Arthritis Despite DMARD Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of rheumatoid arthritis (RA) and inhibition of radiographic progression in patients with active RA who are unresponsive to treatment with disease-modifying antirheumatic drugs (DMARD).
Study identification
- NCT ID
- NCT01604343
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,670 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 15, 2012 (Actual)
- Primary completion
- Sep 2, 2015 (Actual)
- Completion
- Dec 6, 2016 (Actual)
- Last update posted
- Jan 11, 2018
2012 – 2016
United States locations
- U.S. sites
- 48
- U.S. states
- 20
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Glendale | Arizona | — | — |
| Not listed | Mesa | Arizona | — | — |
| Not listed | Peoria | Arizona | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Covina | California | — | — |
| Not listed | El Cajon | California | — | — |
| Not listed | Glendale | California | — | — |
| Not listed | Hemet | California | — | — |
| Not listed | Huntington Beach | California | — | — |
| Not listed | La Jolla | California | — | — |
| Not listed | La Palma | California | — | — |
| Not listed | Whittier | California | — | — |
| Not listed | Aventura | Florida | — | — |
| Not listed | Brandon | Florida | — | — |
| Not listed | Daytona Beach | Florida | — | — |
| Not listed | Lake Mary | Florida | — | — |
| Not listed | Naples | Florida | — | — |
| Not listed | Palm Harbor | Florida | — | — |
| Not listed | Tampa | Florida | — | — |
| Not listed | Zephyrhills | Florida | — | — |
| Not listed | Indianapolis | Indiana | — | — |
| Not listed | Cedar Rapids | Iowa | — | — |
| Not listed | Bowling Green | Kentucky | — | — |
| Not listed | Monroe | Louisiana | — | — |
| Not listed | Wheaton | Maryland | — | — |
| Not listed | Eagan | Minnesota | — | — |
| Not listed | Springfield | Missouri | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | Omaha | Nebraska | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Brooklyn | New York | — | — |
| Not listed | Plainview | New York | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Middleburg Heights | Ohio | — | — |
| Not listed | Edmond | Oklahoma | — | — |
| Not listed | Tulsa | Oklahoma | — | — |
| Not listed | Duncansville | Pennsylvania | — | — |
| Not listed | Wyomissing | Pennsylvania | — | — |
| Not listed | Carrollton | Texas | — | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Lubbock | Texas | — | — |
| Not listed | Mesquite | Texas | — | — |
| Not listed | Kennewick | Washington | — | — |
| Not listed | Beckley | West Virginia | — | — |
| Not listed | Clarksburg | West Virginia | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 108 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01604343, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 11, 2018 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01604343 live on ClinicalTrials.gov.