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Completed Phase 3 Interventional Results available

Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100

ClinicalTrials.gov ID: NCT01605227

Public ClinicalTrials.gov record NCT01605227. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 8:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-blind, Controlled Study of Cabozantinib (XL184) Versus Prednisone in Metastatic Castration-resistant Prostate Cancer Patients Who Have Received Prior Docetaxel and Prior Abiraterone or MDV3100

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the effect of cabozantinib compared to prednisone on overall survival in men with previously treated metastatic castration-resistant prostate cancer with bone-dominant disease who have experienced disease progression on docetaxel-containing chemotherapy and abiraterone or MDV3100.

Study identification

NCT ID
NCT01605227
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Exelixis
Industry
Enrollment
1,028 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 2012 (Type not available)
Primary completion
Sep 2014 (Actual)
Completion
Mar 2015 (Actual)
Last update posted
Mar 14, 2018

2012 – 2015

United States locations

U.S. sites
77
U.S. states
35
U.S. cities
76
Facility City State ZIP Site status
Not listed Birmingham Alabama 35205 —
Not listed Anchorage Alaska 99508 —
Not listed Phoenix Arizona 85016 —
Not listed Scottsdale Arizona 85255 —
Not listed Tucson Arizona 85710 —
Not listed Jonesboro Arkansas 72401 —
Not listed Duarte California 91010 —
Not listed Highland California 92346 —
Not listed La Jolla California 92093 —
Not listed Los Angeles California 90033 —
Not listed Montebello California 90640 —
Not listed Orange California 92868 —
Not listed Palo Alto California 94301 —
Not listed Rancho Mirage California 92270 —
Not listed San Marcos California 92069 —
Not listed St. Helena California 94574 —
Not listed Vallejo California 94589 —
Not listed Aurora Colorado 80045 —
Not listed New Haven Connecticut 06520 —
Not listed Southington Connecticut 06489 —
Not listed Miami Beach Florida 33140 —
Not listed Ocala Florida 34471 —
Not listed Orlando Florida 32806 —
Not listed Tampa Florida 33612 —
Not listed Titusville Florida 32796 —
Not listed Wellington Florida 33449 —
Not listed West Palm Beach Florida 33401 —
Not listed Athens Georgia 30607 —
Not listed Atlanta Georgia 30318 —
Not listed Marietta Georgia 30060 —
Not listed Galesburg Illinois 61401 —
Not listed Niles Illinois 60714 —
Not listed Ames Iowa 50010 —
Not listed Sioux City Iowa 51101 —
Not listed Wichita Kansas 67214 —
Not listed Hazard Kentucky 41701 —
Not listed Louisville Kentucky 40202 —
Not listed Brewer Maine 04412 —
Not listed Baltimore Maryland 21201 —
Not listed Bethesda Maryland 20817 —
Not listed Towson Maryland 21204 —
Not listed Boston Massachusetts 02114 —
Not listed Boston Massachusetts 02118 —
Not listed Methuen Massachusetts 01844 —
Not listed Detroit Michigan 48202 —
Not listed Wyoming Michigan 49509 —
Not listed Minneapolis Minnesota 55455 —
Not listed Jefferson City Missouri 65109 —
Not listed Springfield Missouri 65804 —
Not listed Lincoln Nebraska 68506 —
Not listed Omaha Nebraska 68130 —
Not listed Hackensack New Jersey 07601 —
Not listed Lawrenceville New Jersey 08648 —
Not listed Albany New York 12208 —
Not listed Garden City New York 11530 —
Not listed New York New York 10065 —
Not listed Pinehurst North Carolina 28374 —
Not listed Bismarck North Dakota 58501 —
Not listed Cincinnati Ohio 45219 —
Not listed Columbus Ohio 43221 —
Not listed Portland Oregon 97227 —
Not listed Bryn Mawr Pennsylvania 19010 —
Not listed Hershey Pennsylvania 17033 —
Not listed Lancaster Pennsylvania 17604 —
Not listed Greenville South Carolina 29615 —
Not listed Chattanooga Tennessee 37421 —
Not listed Amarillo Texas 79106 —
Not listed Bedford Texas 76022 —
Not listed Houston Texas 77024 —
Not listed Laredo Texas 78041 —
Not listed San Antonio Texas 78217 —
Not listed Salt Lake City Utah 84112 —
Not listed Burlington Vermont 05405 —
Not listed Fairfax Virginia 22031 —
Not listed Newport News Virginia 23601 —
Not listed Spokane Washington 99204 —
Not listed Green Bay Wisconsin 54311 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 187 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01605227, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 14, 2018 · Synced Oct 27, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01605227 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →