A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)
Public ClinicalTrials.gov record NCT01606761. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Subjects With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of rheumatoid arthritis (RA) in patients with active RA who are unresponsive or intolerant to treatment with anti-TNF-alpha agents.
Study identification
- NCT ID
- NCT01606761
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 878 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 6, 2012 (Actual)
- Primary completion
- Mar 17, 2015 (Actual)
- Completion
- Jan 12, 2016 (Actual)
- Last update posted
- Mar 23, 2018
2012 – 2016
United States locations
- U.S. sites
- 81
- U.S. states
- 28
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Birmingham | Alabama | — | — |
| Not listed | Glendale | Arizona | — | — |
| Not listed | Mesa | Arizona | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Covina | California | — | — |
| Not listed | El Cajon | California | — | — |
| Not listed | Hemet | California | — | — |
| Not listed | Huntington Beach | California | — | — |
| Not listed | La Jolla | California | — | — |
| Not listed | La Palma | California | — | — |
| Not listed | Placentia | California | — | — |
| Not listed | Santa Monica | California | — | — |
| Not listed | Tustin | California | — | — |
| Not listed | Upland | California | — | — |
| Not listed | Victorville | California | — | — |
| Not listed | Whittier | California | — | — |
| Not listed | Hamden | Connecticut | — | — |
| Not listed | Aventura | Florida | — | — |
| Not listed | Boca Raton | Florida | — | — |
| Not listed | Brandon | Florida | — | — |
| Not listed | Daytona Beach | Florida | — | — |
| Not listed | Lake Mary | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Naples | Florida | — | — |
| Not listed | Orlando | Florida | — | — |
| Not listed | Palm Harbor | Florida | — | — |
| Not listed | Plantation | Florida | — | — |
| Not listed | Sarasota | Florida | — | — |
| Not listed | Tampa | Florida | — | — |
| Not listed | Zephyrhills | Florida | — | — |
| Not listed | Boise | Idaho | — | — |
| Not listed | Idaho Falls | Idaho | — | — |
| Not listed | Indianapolis | Indiana | — | — |
| Not listed | Cedar Rapids | Iowa | — | — |
| Not listed | Bowling Green | Kentucky | — | — |
| Not listed | Monroe | Louisiana | — | — |
| Not listed | Shreveport | Louisiana | — | — |
| Not listed | Cumberland | Maryland | — | — |
| Not listed | Frederick | Maryland | — | — |
| Not listed | Hagerstown | Maryland | — | — |
| Not listed | Eagan | Minnesota | — | — |
| Not listed | Rochester | Minnesota | — | — |
| Not listed | Flowood | Mississippi | — | — |
| Not listed | Tupelo | Mississippi | — | — |
| Not listed | Springfield | Missouri | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | Omaha | Nebraska | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Freehold | New Jersey | — | — |
| Not listed | Albuquerque | New Mexico | — | — |
| Not listed | Brooklyn | New York | — | — |
| Not listed | Lake Success | New York | — | — |
| Not listed | Plainview | New York | — | — |
| Not listed | Charlotte | North Carolina | — | — |
| Not listed | Hickory | North Carolina | — | — |
| Not listed | Cincinnati | Ohio | — | — |
| Not listed | Columbus | Ohio | — | — |
| Not listed | Dayton | Ohio | — | — |
| Not listed | Middleburg Heights | Ohio | — | — |
| Not listed | Edmond | Oklahoma | — | — |
| Not listed | Tulsa | Oklahoma | — | — |
| Not listed | Erie | Pennsylvania | — | — |
| Not listed | Pittsburgh | Pennsylvania | — | — |
| Not listed | Wyomissing | Pennsylvania | — | — |
| Not listed | East Greenwich | Rhode Island | — | — |
| Not listed | Charleston | South Carolina | — | — |
| Not listed | Austin | Texas | — | — |
| Not listed | Carrollton | Texas | — | — |
| Not listed | Corpus Christi | Texas | — | — |
| Not listed | Cypress | Texas | — | — |
| Not listed | Dallas | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Katy | Texas | — | — |
| Not listed | Lubbock | Texas | — | — |
| Not listed | Mesquite | Texas | — | — |
| Not listed | Richmond | Texas | — | — |
| Not listed | Victoria | Texas | — | — |
| Not listed | Kennewick | Washington | — | — |
| Not listed | Seattle | Washington | — | — |
| Not listed | Beckley | West Virginia | — | — |
| Not listed | Clarksburg | West Virginia | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 120 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01606761, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 23, 2018 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01606761 live on ClinicalTrials.gov.