ClinicalTrials.gov record
Evaluation of Patient Retention of Fingolimod vs. Currently Approved Disease Modifying Therapy in Patients With Relapsing Remitting Multiple Sclerosis.
ClinicalTrials.gov ID: NCT01623596
Public ClinicalTrials.gov record NCT01623596. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 12-month, Prospective, Randomized, Active-controlled, Open-label Study to Evaluate the Patient Retention of Fingolimod vs. Approved First-line Disease Modifying Therapies in Adults With Relapsing Remitting Multiple Sclerosis (PREFERMS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A 12 month study where 852 patients with relapsing remitting MS will be randomized 1:1 to fingolimod or approved disease modifying therapy. Patients will be be treatment naive or have only been treated with one class of DMT (Interferon beta preparation or glatiramer acetate) . Patients will be able to switch to different treatment for safety, efficacy, tolerability or convenience during the study. Primary objective is to evaluate efficacy of fingolimod by assessing patients retention on treatment. Secondary objectives are to compare reasons for discontinuation, adverse events, cognitive impairment, medication satisfaction and change in brain volume measured by MRI.
Study identification
- NCT ID
- NCT01623596
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 881 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 7, 2012
- Primary completion
- Jul 12, 2015
- Completion
- Jul 12, 2015
- Last update posted
- Jan 4, 2021
2012 – 2015
United States locations
- U.S. sites
- 122
- U.S. states
- 38
- U.S. cities
- 114
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novartis Investigative Site | Cullman | Alabama | 35058 | — |
| Novartis Investigative Site | Phoenix | Arizona | 85004 | — |
| Novartis Investigative Site | Sun City | Arizona | 85351 | — |
| Novartis Investigative Site | Tucson | Arizona | 85741 | — |
| Novartis Investigative Site | Sherwood | Arkansas | 72120 | — |
| Novartis Investigative Site | Fullerton | California | 92835 | — |
| Novartis Investigative Site | Oceanside | California | 92056 | — |
| Novartis Investigative Site | San Francisco | California | 94117 | — |
| Novartis Investigative Site | Walnut Creek | California | 94598 | — |
| Novartis Investigative Site | Basalt | Colorado | 81621 | — |
| Novartis Investigative Site | Boulder | Colorado | 80301 | — |
| Novartis Investigative Site | Denver | Colorado | 80209 | — |
| Novartis Investigative Site | Denver | Colorado | 80210 | — |
| Novartis Investigative Site | Fort Collins | Colorado | 80528 | — |
| Novartis Investigative Site | Fairfield | Connecticut | 06824 | — |
| Novartis Investigative Site | New London | Connecticut | 06320 | — |
| Novartis Investigative Site | Dover | Delaware | 19901 | — |
| Novartis Investigative Site | Atlantis | Florida | 33462-6608 | — |
| Novartis Investigative Site | Bradenton | Florida | 34205 | — |
| Novartis Investigative Site | Delray Beach | Florida | 33445 | — |
| Novartis Investigative Site | Hollywood | Florida | 33021 | — |
| Novartis Investigative Site | Jacksonville | Florida | 32216 | — |
| Novartis Investigative Site | North Palm Beach | Florida | 33408 | — |
| Novartis Investigative Site | Plantation | Florida | 33324 | — |
| Novartis Investigative Site | Pompano Beach | Florida | 33060 | — |
| Novartis Investigative Site | Port Charlotte | Florida | 33952 | — |
| Novartis Investigative Site | Port Orange | Florida | 32127 | — |
| Novartis Investigative Site | Sarasota | Florida | 34233 | — |
| Novartis Investigative Site | Sarasota | Florida | 34243 | — |
| Novartis Investigative Site | St. Petersburg | Florida | 33713 | — |
| Novartis Investigative Site | Tallahassee | Florida | 32308 | — |
| Novartis Investigative Site | Tampa | Florida | 33609 | — |
| Novartis Investigative Site | West Palm Beach | Florida | 33407 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30312 | — |
| Novartis Investigative Site | Columbus | Georgia | 31904 | — |
| Novartis Investigative Site | Decatur | Georgia | 30083 | — |
| Novartis Investigative Site | Suwanee | Georgia | 30024 | — |
| Novartis Investigative Site | Flossmoor | Illinois | 60422 | — |
| Novartis Investigative Site | Northbrook | Illinois | 60062 | — |
| Novartis Investigative Site | Anderson | Indiana | 46011 | — |
| Novartis Investigative Site | Indianapolis | Indiana | 46227 | — |
| Novartis Investigative Site | Indianapolis | Indiana | 46256 | — |
| Novartis Investigative Site | Des Moines | Iowa | 50314-2611 | — |
| Novartis Investigative Site | Overland Park | Kansas | — | — |
| Novartis Investigative Site | Wichita | Kansas | 67214 | — |
| Novartis Investigative Site | Hawesville | Kentucky | 42384 | — |
| Novartis Investigative Site | Lexington | Kentucky | 40504 | — |
| Novartis Investigative Site | Madisonville | Kentucky | 42431 | — |
| Novartis Investigative Site | Alexandria | Louisiana | 71301 | — |
| Novartis Investigative Site | Baton Rouge | Louisiana | 70809 | — |
| Novartis Investigative Site | New Orleans | Louisiana | 70115 | — |
| Novartis Investigative Site | Annapolis | Maryland | 21401 | — |
| Novartis Investigative Site | Fulton | Maryland | 20759 | — |
| Novartis Investigative Site | New Bedford | Massachusetts | 02740 | — |
| Novartis Investigative Site | North Dartmouth | Massachusetts | 02747 | — |
| Novartis Investigative Site | Springfield | Massachusetts | 01104 | — |
| Novartis Investigative Site | Watertown | Massachusetts | 02472 | — |
| Novartis Investigative Site | Worcester | Massachusetts | 01608 | — |
| Novartis Investigative Site | Kalamazoo | Michigan | 49007 | — |
| Novartis Investigative Site | Traverse City | Michigan | 49684-2340 | — |
| Novartis Investigative Site | Nixa | Missouri | 65714-7807 | — |
| Novartis Investigative Site | North Kansas City | Missouri | 64116 | — |
| Novartis Investigative Site | St Louis | Missouri | 63104 | — |
| Novartis Investigative Site | Las Vegas | Nevada | 89121 | — |
| Novartis Investigative Site | Las Vegas | Nevada | 89123 | — |
| Novartis Investigative Site | Las Vegas | Nevada | 89144 | — |
| Novartis Investigative Site | Flemington | New Jersey | 08822 | — |
| Novartis Investigative Site | Teaneck | New Jersey | 07666 | — |
| Novartis Investigative Site | Toms River | New Jersey | 08755 | — |
| Novartis Investigative Site | Albuquerque | New Mexico | 87108 | — |
| Novartis Investigative Site | Albany | New York | 12208 | — |
| Novartis Investigative Site | Amherst | New York | 14226 | — |
| Novartis Investigative Site | Kingston | New York | 12401 | — |
| Novartis Investigative Site | Latham | New York | 12110 | — |
| Novartis Investigative Site | New York | New York | 10003 | — |
| Novartis Investigative Site | Patchogue | New York | 11772 | — |
| Novartis Investigative Site | The Bronx | New York | 10467-2490 | — |
| Novartis Investigative Site | Asheville | North Carolina | 28806 | — |
| Novartis Investigative Site | Charlotte | North Carolina | 28202 | — |
| Novartis Investigative Site | Charlotte | North Carolina | 28204 | — |
| Novartis Investigative Site | Greensboro | North Carolina | 27401 | — |
| Novartis Investigative Site | Greenville | North Carolina | 27834 | — |
| Novartis Investigative Site | Raleigh | North Carolina | 27607 | — |
| Novartis Investigative Site | Salisbury | North Carolina | 28144 | — |
| Novartis Investigative Site | Winston-Salem | North Carolina | 27103 | — |
| Novartis Investigative Site | Grand Forks | North Dakota | 58201 | — |
| Novartis Investigative Site | Akron | Ohio | 44320 | — |
| Novartis Investigative Site | Bellevue | Ohio | 44811 | — |
| Novartis Investigative Site | Canton | Ohio | 44718 | — |
| Novartis Investigative Site | Cincinnati | Ohio | 45219 | — |
| Novartis Investigative Site | Columbus | Ohio | 43221 | — |
| Novartis Investigative Site | Dayton | Ohio | 45408 | — |
| Novartis Investigative Site | Toledo | Ohio | 43623 | — |
| Novartis Investigative Site | Oklahoma City | Oklahoma | 73104 | — |
| Novartis Investigative Site | Oklahoma City | Oklahoma | 73112 | — |
| Novartis Investigative Site | Eugene | Oregon | 97401 | — |
| Novartis Investigative Site | Greensburg | Pennsylvania | 15601 | — |
| Novartis Investigative Site | Hershey | Pennsylvania | 17033-0850 | — |
| Novartis Investigative Site | Pittsburgh | Pennsylvania | 15212 | — |
| Novartis Investigative Site | Cranston | Rhode Island | 02920 | — |
| Novartis Investigative Site | Old Point Station | South Carolina | 29707 | — |
| Novartis Investigative Site | Spartanburg | South Carolina | 29302 | — |
| Novartis Investigative Site | Spartanburg | South Carolina | 29307 | — |
| Novartis Investigative Site | Cordova | Tennessee | 38018 | — |
| Novartis Investigative Site | Knoxville | Tennessee | 37920 | — |
| Novartis Investigative Site | Nashville | Tennessee | 37205 | — |
| Novartis Investigative Site | Colleyville | Texas | 76034 | — |
| Novartis Investigative Site | Houston | Texas | 77074 | — |
| Novartis Investigative Site | Lubbock | Texas | 79410 | — |
| Novartis Investigative Site | North Richland Hills | Texas | 76180 | — |
| Novartis Investigative Site | Plano | Texas | 75075 | — |
| Novartis Investigative Site | Round Rock | Texas | 78681 | — |
| Novartis Investigative Site | San Antonio | Texas | 78229 | — |
| Novartis Investigative Site | Orem | Utah | 84058 | — |
| Novartis Investigative Site | Alexandria | Virginia | 22310 | — |
| Novartis Investigative Site | Norfolk | Virginia | 23507 | — |
| Novartis Investigative Site | Vienna | Virginia | 22182 | — |
| Novartis Investigative Site | Bothell | Washington | 98011 | — |
| Novartis Investigative Site | Seattle | Washington | 98101 | — |
| Novartis Investigative Site | Tacoma | Washington | 98405 | — |
| Novartis Investigative Site | Morgantown | West Virginia | 26506-9260 | — |
| Novartis Investigative Site | Neenah | Wisconsin | 54956 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01623596, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 4, 2021 · Synced Sep 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01623596 live on ClinicalTrials.gov.