A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Anti-TNFa Biologics
Public ClinicalTrials.gov record NCT01636817. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Randomised, Double Blind, Placebo-controlled, Multiple Dose, Phase 2b, 24 Week Trial Followed by an Open Label Extension of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Anti-TNFa Biologics
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This trial is conducted in Europe, North America and South America. The aim of this trial is to investigate the clinical efficacy of NNC0109-0012, a human monoclonal antibody, compared to placebo when administered as weekly s.c. (subcutaneous, under the skin) injections to patients with active rheumatoid arthritis (RA) who are inadequate responders to anti-TNFa biologics and are on a stable background of methotrexate (MTX) therapy.
Study identification
- NCT ID
- NCT01636817
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 239 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2012 (Type not available)
- Primary completion
- Nov 2014 (Actual)
- Completion
- Nov 2014 (Actual)
- Last update posted
- Sep 5, 2018
2012 – 2014
United States locations
- U.S. sites
- 92
- U.S. states
- 32
- U.S. cities
- 84
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novo Nordisk Investigational Site | Huntsville | Alabama | 35801 | — |
| Novo Nordisk Investigational Site | Tuscaloosa | Alabama | 35406 | — |
| Novo Nordisk Investigational Site | Mesa | Arizona | 85202 | — |
| Novo Nordisk Investigational Site | Phoenix | Arizona | 85037 | — |
| Novo Nordisk Investigational Site | Scottsdale | Arizona | 85258-4523 | — |
| Novo Nordisk Investigational Site | Glendale | California | 91204 | — |
| Novo Nordisk Investigational Site | Hemet | California | 92543 | — |
| Novo Nordisk Investigational Site | Huntington Beach | California | 92646 | — |
| Novo Nordisk Investigational Site | La Mesa | California | 91942 | — |
| Novo Nordisk Investigational Site | Lakewood | California | 90712 | — |
| Novo Nordisk Investigational Site | Long Beach | California | 90806 | — |
| Novo Nordisk Investigational Site | Long Beach | California | 90808-2146 | — |
| Novo Nordisk Investigational Site | Los Angeles | California | 90022 | — |
| Novo Nordisk Investigational Site | Placentia | California | 92870 | — |
| Novo Nordisk Investigational Site | San Diego | California | 92101 | — |
| Novo Nordisk Investigational Site | Santa Monica | California | 90409 | — |
| Novo Nordisk Investigational Site | Upland | California | 91786 | — |
| Novo Nordisk Investigational Site | Boca Raton | Florida | 33486 | — |
| Novo Nordisk Investigational Site | Fort Lauderdale | Florida | 33334 | — |
| Novo Nordisk Investigational Site | Gainesville | Florida | 32607 | — |
| Novo Nordisk Investigational Site | Jupiter | Florida | 33468 | — |
| Novo Nordisk Investigational Site | New Port Richey | Florida | 34652 | — |
| Novo Nordisk Investigational Site | Ocala | Florida | 34474 | — |
| Novo Nordisk Investigational Site | Orlando | Florida | 32804 | — |
| Novo Nordisk Investigational Site | Tampa | Florida | 33613 | — |
| Novo Nordisk Investigational Site | Venice | Florida | 34292 | — |
| Novo Nordisk Investigational Site | West Palm Beach | Florida | 33407 | — |
| Novo Nordisk Investigational Site | Decatur | Georgia | 30033 | — |
| Novo Nordisk Investigational Site | Idaho Falls | Idaho | 83404 | — |
| Novo Nordisk Investigational Site | Rock Island | Illinois | 61201 | — |
| Novo Nordisk Investigational Site | Springfield | Illinois | 62704 | — |
| Novo Nordisk Investigational Site | South Bend | Indiana | 46601 | — |
| Novo Nordisk Investigational Site | Cedar Rapids | Iowa | 52401-2112 | — |
| Novo Nordisk Investigational Site | Kansas City | Kansas | 66160 | — |
| Novo Nordisk Investigational Site | Wichita | Kansas | 67206 | — |
| Novo Nordisk Investigational Site | Elizabethtown | Kentucky | 42701-2988 | — |
| Novo Nordisk Investigational Site | Lake Charles | Louisiana | 70601 | — |
| Novo Nordisk Investigational Site | Shreveport | Louisiana | 71105 | — |
| Novo Nordisk Investigational Site | Baltimore | Maryland | 21239 | — |
| Novo Nordisk Investigational Site | Columbia | Maryland | 21045 | — |
| Novo Nordisk Investigational Site | Cumberland | Maryland | 21502 | — |
| Novo Nordisk Investigational Site | Hagerstown | Maryland | 21740 | — |
| Novo Nordisk Investigational Site | Worcester | Massachusetts | 01605 | — |
| Novo Nordisk Investigational Site | Ann Arbor | Michigan | 48109-0100 | — |
| Novo Nordisk Investigational Site | Battle Creek | Michigan | 49018 | — |
| Novo Nordisk Investigational Site | Flowood | Mississippi | 39232-9306 | — |
| Novo Nordisk Investigational Site | Flowood | Mississippi | 39232 | — |
| Novo Nordisk Investigational Site | St Louis | Missouri | 63117 | — |
| Novo Nordisk Investigational Site | St Louis | Missouri | 63139-2338 | — |
| Novo Nordisk Investigational Site | St Louis | Missouri | 63141-6819 | — |
| Novo Nordisk Investigational Site | Lincoln | Nebraska | 68516 | — |
| Novo Nordisk Investigational Site | Clifton | New Jersey | 07012 | — |
| Novo Nordisk Investigational Site | Freehold | New Jersey | 07728 | — |
| Novo Nordisk Investigational Site | Toms River | New Jersey | 08755 | — |
| Novo Nordisk Investigational Site | Albuquerque | New Mexico | 87102 | — |
| Novo Nordisk Investigational Site | Albany | New York | 12206 | — |
| Novo Nordisk Investigational Site | Brooklyn | New York | 11201-4326 | — |
| Novo Nordisk Investigational Site | Lake Success | New York | 11042 | — |
| Novo Nordisk Investigational Site | Chapel Hill | North Carolina | 27599 | — |
| Novo Nordisk Investigational Site | Charlotte | North Carolina | 28210 | — |
| Novo Nordisk Investigational Site | Greensboro | North Carolina | 27408 | — |
| Novo Nordisk Investigational Site | Raleigh | North Carolina | 27617 | — |
| Novo Nordisk Investigational Site | Wilmington | North Carolina | 28401-6442 | — |
| Novo Nordisk Investigational Site | Cincinnati | Ohio | 45219 | — |
| Novo Nordisk Investigational Site | Columbus | Ohio | 43203 | — |
| Novo Nordisk Investigational Site | Toledo | Ohio | 43606 | — |
| Novo Nordisk Investigational Site | Norman | Oklahoma | 73069 | — |
| Novo Nordisk Investigational Site | Oklahoma City | Oklahoma | 73103 | — |
| Novo Nordisk Investigational Site | Tulsa | Oklahoma | 74135 | — |
| Novo Nordisk Investigational Site | Bend | Oregon | 97701 | — |
| Novo Nordisk Investigational Site | Lake Oswego | Oregon | 07035 | — |
| Novo Nordisk Investigational Site | Hershey | Pennsylvania | 17033-2360 | — |
| Novo Nordisk Investigational Site | Charleston | South Carolina | 29406 | — |
| Novo Nordisk Investigational Site | Charleston | South Carolina | 29407-7757 | — |
| Novo Nordisk Investigational Site | Columbia | South Carolina | 29204-2409 | — |
| Novo Nordisk Investigational Site | Orangeburg | South Carolina | 29118 | — |
| Novo Nordisk Investigational Site | Jackson | Tennessee | 38305 | — |
| Novo Nordisk Investigational Site | Memphis | Tennessee | 38104 | — |
| Novo Nordisk Investigational Site | Memphis | Tennessee | 38119 | — |
| Novo Nordisk Investigational Site | Amarillo | Texas | 79124 | — |
| Novo Nordisk Investigational Site | Austin | Texas | 78721 | — |
| Novo Nordisk Investigational Site | Carrollton | Texas | 75007 | — |
| Novo Nordisk Investigational Site | Houston | Texas | 77008 | — |
| Novo Nordisk Investigational Site | Houston | Texas | 77034 | — |
| Novo Nordisk Investigational Site | Houston | Texas | 77090 | — |
| Novo Nordisk Investigational Site | McKinney | Texas | 75071 | — |
| Novo Nordisk Investigational Site | Sugar Land | Texas | 77479 | — |
| Novo Nordisk Investigational Site | Waco | Texas | 76708-3244 | — |
| Novo Nordisk Investigational Site | Arlington | Virginia | 22205 | — |
| Novo Nordisk Investigational Site | Seattle | Washington | 98122 | — |
| Novo Nordisk Investigational Site | Tacoma | Washington | 98405 | — |
| Novo Nordisk Investigational Site | Beckley | West Virginia | 25801-2805 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 72 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01636817, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 5, 2018 · Synced Nov 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01636817 live on ClinicalTrials.gov.