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Completed Phase 2 Interventional Results available

Alisertib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus

ClinicalTrials.gov ID: NCT01637961

Public ClinicalTrials.gov record NCT01637961. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Evaluation of MLN8237 (NSC# 747888) in the Treatment of Recurrent or Persistent Leiomyosarcoma of the Uterus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This phase II trial studies how well alisertib works in treating patients with leiomyosarcoma of the uterus that has come back or persistent. Alisertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Study identification

NCT ID
NCT01637961
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
23 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2012 (Type not available)
Primary completion
Aug 2014 (Actual)
Completion
Feb 11, 2017 (Actual)
Last update posted
Jul 23, 2019

2012 – 2017

United States locations

U.S. sites
50
U.S. states
19
U.S. cities
40
Facility City State ZIP Site status
Hartford Hospital Hartford Connecticut 06102 —
Smilow Cancer Hospital Care Center at Saint Francis Hartford Connecticut 06105 —
The Hospital of Central Connecticut New Britain Connecticut 06050 —
Florida Hospital Orlando Orlando Florida 32803 —
University of Hawaii Cancer Center Honolulu Hawaii 96813 —
Saint Alphonsus Cancer Care Center-Boise Boise Idaho 83706 —
University of Chicago Comprehensive Cancer Center Chicago Illinois 60637 —
Sudarshan K Sharma MD Limted-Gynecologic Oncology Hinsdale Illinois 60521 —
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis Indiana 46202 —
Saint Vincent Hospital and Health Care Center Indianapolis Indiana 46260 —
McFarland Clinic PC-William R Bliss Cancer Center Ames Iowa 50010 —
Iowa Methodist Medical Center Des Moines Iowa 50309 —
Iowa-Wide Oncology Research Coalition NCORP Des Moines Iowa 50309 —
Medical Oncology and Hematology Associates-Des Moines Des Moines Iowa 50309 —
Medical Oncology and Hematology Associates-Laurel Des Moines Iowa 50314 —
Mercy Medical Center - Des Moines Des Moines Iowa 50314 —
Iowa Lutheran Hospital Des Moines Iowa 50316 —
University of Iowa/Holden Comprehensive Cancer Center Iowa City Iowa 52242 —
Saint Joseph Mercy Hospital Ann Arbor Michigan 48106-0995 —
Michigan Cancer Research Consortium NCORP Ann Arbor Michigan 48106 —
Beaumont Hospital-Dearborn Dearborn Michigan 48124 —
Saint John Hospital and Medical Center Detroit Michigan 48236 —
Hurley Medical Center Flint Michigan 48502 —
Genesys Regional Medical Center Grand Blanc Michigan 48439 —
Allegiance Health Jackson Michigan 49201 —
Sparrow Hospital Lansing Michigan 48912 —
Saint Mary Mercy Hospital Livonia Michigan 48154 —
Saint Joseph Mercy Oakland Pontiac Michigan 48341 —
Lake Huron Medical Center Port Huron Michigan 48060 —
Saint Mary's of Michigan Saginaw Michigan 48601 —
University of Mississippi Medical Center Jackson Mississippi 39216 —
Cancer Research for the Ozarks NCORP Springfield Missouri 65804 —
Mercy Hospital Springfield Springfield Missouri 65804 —
CoxHealth South Hospital Springfield Missouri 65807 —
Washington University School of Medicine St Louis Missouri 63110 —
Nebraska Methodist Hospital Omaha Nebraska 68114 —
Memorial Sloan-Kettering Cancer Center New York New York 10065 —
UNC Lineberger Comprehensive Cancer Center Chapel Hill North Carolina 27599 —
Carolinas Medical Center/Levine Cancer Institute Charlotte North Carolina 28203 —
Southeast Clinical Oncology Research (SCOR) Consortium NCORP Winston-Salem North Carolina 27104 —
Case Western Reserve University Cleveland Ohio 44106 —
Riverside Methodist Hospital Columbus Ohio 43214 —
Lake University Ireland Cancer Center Mentor Ohio 44060 —
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104 —
Oklahoma Cancer Specialists and Research Institute-Tulsa Tulsa Oklahoma 74146 —
Abington Memorial Hospital Abington Pennsylvania 19001 —
Reading Hospital West Reading Pennsylvania 19611 —
Women and Infants Hospital Providence Rhode Island 02905 —
AnMed Health Cancer Center Anderson South Carolina 29621 —
Memorial Hermann Texas Medical Center Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01637961, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 23, 2019 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01637961 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →