The Performance of the APPY1 Test in the Evaluation of Possible Acute Appendicitis
Public ClinicalTrials.gov record NCT01652170. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The Performance of the APPY1 Test in the Evaluation of Possible Acute Appendicitis in Children, Adolescents, and Young Adults Presenting to the Emergency Department
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will consist of a brief interaction with the subject or parent or guardian to obtain consent, collect a blood sample, medical history, and physical examination of those who meet the inclusion criteria. The blood sample will be tested for the WBC value, as well as processed into plasma in order to compute the APPY1 Test result, which is based on a combination of the WBC value and the plasma MRP 8/14 and CRP concentrations received from the APPY1 Test cassette. There will be a 2-week (14 days +/- 3) follow-up telephone call for those subjects that were discharged from the ED without an appendectomy or diagnosis of acute appendicitis. Use of the APPY1 Test to help identify low risk patients could significantly reduce the use of CT scans in diagnosis of AA, thereby reducing the exposure to ionizing radiation in children, adolescents, and young adults.
Study identification
- NCT ID
- NCT01652170
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 2,201 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 2 Years to 20 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2012
- Primary completion
- Jan 31, 2014
- Completion
- Jan 31, 2014
- Last update posted
- Mar 23, 2014
2013 – 2014
United States locations
- U.S. sites
- 29
- U.S. states
- 19
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Children's Hosptial | Phoenix | Arizona | 85016 | — |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | — |
| UC Davis | Sacramento | California | 95817 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida, College of Medicine | Jacksonville | Florida | 32209 | — |
| All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| Emory-Egleston (CHOA) | Atlanta | Georgia | 30322 | — |
| Scottish Rite (CHOA) | Atlanta | Georgia | 30342 | — |
| Newton-Wellesley Hospital | Newton | Massachusetts | 02462 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| South Shore Hospital | Weymouth | Massachusetts | 02190 | — |
| University of Michigan, Mott Children's Hospital | Ann Arbor | Michigan | 48109 | — |
| Spectrum Health System | Grand Rapids | Michigan | 49503 | — |
| The Children's Mercy Hosptial | Kansas City | Missouri | 64108 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03766 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27175 | — |
| Cincinnati Children's Hospital | Cincinnati | Ohio | 45229 | — |
| Cleveland Clinic | Cleveland | Ohio | 44495 | — |
| Nationwide Children's | Columbus | Ohio | 43205 | — |
| OHSU | Portland | Oregon | 97239 | — |
| Children's Hospital of Pittsburg | Pittsburgh | Pennsylvania | 15224 | — |
| Rhode Island Hospital - Hasbro | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Vanderbilt Children's Hospital | Nashville | Tennessee | 37232 | — |
| Dell Children's Medical Center | Austin | Texas | 78723 | — |
| St. Joseph's Regional Health Center | Bryan | Texas | 77802 | — |
| St. Joseph's Emergency Center | College Station | Texas | 77845 | — |
| Dallas Children's Hospital | Dallas | Texas | 75235 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01652170, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 23, 2014 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01652170 live on ClinicalTrials.gov.