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Completed Phase 2 Interventional

Safety and Efficacy Study of MEHD7945A + FOLFIRI Versus Cetuximab + FOLFIRI as Second Line Therapy in Participants With KRAS Wild-Type Metastatic Colorectal Cancer (mCRC)

ClinicalTrials.gov ID: NCT01652482

Public ClinicalTrials.gov record NCT01652482. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 9:24 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Multicenter, Open-Label, Randomized Study Evaluating the Efficacy and Safety of MEHD7945A + FOLFIRI Versus Cetuximab + FOLFIRI in Second Line in Patients With KRAS Wildtype Metastatic Colorectal Cancer

Study identification

NCT ID
NCT01652482
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Genentech, Inc.
Industry
Enrollment
135 participants

Conditions and interventions

Interventions

  • 5-fluorouracil Drug
  • Cetuximab Drug
  • Irinotecan Drug
  • Leucovorin Drug
  • MEHD7945A Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2012
Primary completion
Oct 31, 2014
Completion
Oct 31, 2014
Last update posted
Nov 1, 2016

2012 – 2014

United States locations

U.S. sites
19
U.S. states
12
U.S. cities
17
Facility City State ZIP Site status
Not listed Bakersfield California 93309
Not listed Fullerton California 92835
Not listed Los Angeles California 90033
Not listed Los Angeles California 90095
Not listed San Luis Obispo California 93454
Not listed Santa Barbara California 93105
Not listed Aurora Colorado 80045
Not listed Orange Park Florida 32073
Not listed Harvey Illinois 60426
Not listed Paducah Kentucky 42003
Not listed Rockville Maryland 20850
Not listed Boston Massachusetts 02114
Not listed Boston Massachusetts 02215
Not listed Detroit Michigan 48201
Not listed Jefferson City Missouri 65109
Not listed Las Vegas Nevada 89148
Not listed Philadelphia Pennsylvania 19104
Not listed Kirkland Washington 98034
Not listed Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01652482, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 1, 2016 · Synced May 11, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01652482 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →