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Completed Phase 1 Interventional

Study of XL888 With Vemurafenib for Patients With Unresectable BRAF Mutated Stage III/IV Melanoma

ClinicalTrials.gov ID: NCT01657591

Public ClinicalTrials.gov record NCT01657591. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 9:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase I Study of Escalating Doses of XL888 With Vemurafenib for Patients With Unresectable BRAF Mutated Stage III/IV Melanoma

Study identification

NCT ID
NCT01657591
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Enrollment
21 participants

Conditions and interventions

Conditions

Interventions

  • Vemurafenib Drug
  • XL888 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 26, 2012
Primary completion
Sep 19, 2016
Completion
Sep 20, 2021
Last update posted
Jan 18, 2023

2012 – 2021

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
H. Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01657591, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 18, 2023 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01657591 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →