Study of Nivolumab (BMS-936558) vs. Everolimus in Pre-Treated Advanced or Metastatic Clear-cell Renal Cell Carcinoma (CheckMate 025)
Public ClinicalTrials.gov record NCT01668784. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open-Label, Phase 3 Study of Nivolumab (BMS-936558) vs. Everolimus in Subjects With Advanced or Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to compare the clinical benefit, as measured by duration of overall survival, of Nivolumab vs. Everolimus in subjects with advanced or metastatic clear-cell renal cell carcinoma who have received prior anti-angiogenic therapy
Study identification
- NCT ID
- NCT01668784
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 821 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 9, 2012 (Actual)
- Primary completion
- May 6, 2015 (Actual)
- Completion
- Jul 19, 2021 (Actual)
- Last update posted
- Aug 9, 2022
2012 – 2021
United States locations
- U.S. sites
- 39
- U.S. states
- 22
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0182 | Fayetteville | Arkansas | 72703 | — |
| UCSD Moores Cancer Center | La Jolla | California | 92093-0698 | — |
| Local Institution - 0024 | Los Angeles | California | 90033 | — |
| University Of Southern California | Los Angeles | California | 90033 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| Ucsf Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94115 | — |
| Stanford Cancer Institute | Stanford | California | 94305 | — |
| University Of Colorado | Aurora | Colorado | 80045 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Local Institution - 0027 | Washington D.C. | District of Columbia | 20007 | — |
| H. Lee Moffitt Cancer Center & Research Institute | Tampa | Florida | 33612-9497 | — |
| Winship Cancer Institute. | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Loyola University Chicago | Maywood | Illinois | 60153 | — |
| Indiana University Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| University Of Iowa Hospitals And Clinics | Iowa City | Iowa | 52242 | — |
| Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins | Baltimore | Maryland | 21231-1000 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| University Of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-5946 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Memorial Sloan Kettering Nassau | New York | New York | 10065 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Medical University Of South Carolina | Charleston | South Carolina | 29425 | — |
| St Francis Hospital | Greenville | South Carolina | 29601 | — |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232-6307 | — |
| Ut Southwestern Medical Center | Dallas | Texas | 75390-9133 | — |
| Local Institution - 0139 | Houston | Texas | 77030-4009 | — |
| CTRC at UTHSC San Antonio | San Antonio | Texas | 78229 | — |
| Local Institution - 0076 | Richmond | Virginia | 23229 | — |
| Local Institution - 0009 | Seattle | Washington | 98109 | — |
| University Of Washington | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 129 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01668784, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 9, 2022 · Synced Oct 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01668784 live on ClinicalTrials.gov.