A Study of Bitopertin (RO4917838) in Combination With Selective Serotonin Reuptake Inhibitors (SSRIs) in Participants With Obsessive-Compulsive Disorder (OCD)
Public ClinicalTrials.gov record NCT01674361. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate Efficacy and Safety of RO4917838 in Combination With Selective Serotonin Reuptake Inhibitors in Patients With Obsessive Compulsive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This multicenter, randomized, double-blind, parallel-group, placebo-controlled study will evaluate the efficacy and safety of bitopertin in combination with SSRI in participants with obsessive-compulsive disorder. Participants will be randomized to receive either bitopertin 30 milligrams (mg) or bitopertin 10 mg or placebo orally daily in addition to their background therapy with an SSRI. Participants will be allocated to one of two strata. Participants in Stratum 1 will start study drug on Day 1. Participants in Stratum 2 will receive placebo from Day 1 (placebo lead-in) and will then start study drug at the Week 2 visit. Participants in both strata will receive the study drug in addition to their background therapy with an SSRI until Week 16.
Study identification
- NCT ID
- NCT01674361
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 99 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2012 (Actual)
- Primary completion
- Apr 30, 2015 (Actual)
- Completion
- Apr 30, 2015 (Actual)
- Last update posted
- Aug 2, 2017
2012 – 2015
United States locations
- U.S. sites
- 27
- U.S. states
- 19
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Excell Research | Oceanside | California | 92056 | — |
| Stanford University School of Medicine | Stanford | California | 94305 | — |
| Yale University School of Medicine; Neuroscience Research Training Program | New Haven | Connecticut | 06519 | — |
| Compass Research North, LLC | Leesburg | Florida | 34748 | — |
| Medical Research Group of Central Florida | Orange City | Florida | 3273 | — |
| University of South Florida | St. Petersburg | Florida | 33701 | — |
| University of South Florida | Tampa | Florida | 33613-4706 | — |
| iResearch Atlanta | Decatur | Georgia | 30030 | — |
| Carman Research | Smyrna | Georgia | 30080 | — |
| Uni of Chicago; Centre For Advanced Medicine | Chicago | Illinois | 60637 | — |
| Louisiana Research Associates | New Orleans | Louisiana | 70114 | — |
| Massachusetts General Hospital - East | Boston | Massachusetts | 02114 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| Ambulatory Research Center (ARC), Department of Psychiatry | Minneapolis | Minnesota | 55454 | — |
| Precise Research Centers | Flowood | Mississippi | 39232 | — |
| St Louis Clinical Trials | St Louis | Missouri | 63141 | — |
| Mount Sinai School of Medicine; Department of Psychiatry | New York | New York | 10029 | — |
| Medical Research Network - New York | New York | New York | 10128 | — |
| Finger Lakes Clinical Research | Rochester | New York | 14618 | — |
| North Star Research | Middleburg Heights | Ohio | 44130 | — |
| Ips Research Company | Oklahoma City | Oklahoma | 73103 | — |
| Keystone Clinical Studies, LLC | Norristown | Pennsylvania | 19403 | — |
| Butler Hospital - Department of Psychiatry and Human Behavior | Providence | Rhode Island | 02906 | — |
| Clinical Neuroscience Solutions,Inc | Memphis | Tennessee | 38119 | — |
| FutureSearch Trials, LP | Austin | Texas | 78731 | — |
| Eastside Therapeutic Resource | Kirkland | Washington | 98033 | — |
| Dean Foundation | Middleton | Wisconsin | 53562 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01674361, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 2, 2017 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01674361 live on ClinicalTrials.gov.