A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma
Public ClinicalTrials.gov record NCT01677858. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The study had the following primary objectives: * Phase 1: to determine the maximum tolerated dose (MTD) of once-weekly (QW) carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma who have received 1 to 3 prior therapies * Phase 2: to estimate the overall response rate (ORR) for patients with relapsed or refractory multiple myeloma who received 1 to 3 prior therapies treated with carfilzomib and dexamethasone QW at the MTD established in phase 1.
Study identification
- NCT ID
- NCT01677858
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 116 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 4, 2012 (Type not available)
- Primary completion
- Jul 22, 2016 (Actual)
- Completion
- Oct 31, 2018 (Actual)
- Last update posted
- Sep 23, 2022
2012 – 2018
United States locations
- U.S. sites
- 35
- U.S. states
- 15
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Oncology Associates | Tucson | Arizona | — | — |
| Comprehensive Blood and Cancer Center (CCBC) | Bakersfield | California | — | — |
| California Cancer Associates for Research and Excellence | Encinitas | California | — | — |
| Robert A. Moss, M.D., FACP, Inc. | Fountain Valley | California | — | — |
| California Cancer Associates for Research and Excellence | Fresno | California | — | — |
| Cedars-Sinai Medical Center | Los Angeles | California | — | — |
| Monterey Bay Oncology | Salinas | California | — | — |
| Sansum Clinic | Santa Barbara | California | — | — |
| Central Coast Medical Oncology Corporation | Santa Maria | California | — | — |
| James R. Berenson M.D. Inc. | West Hollywood | California | — | — |
| The Oncology Insititute of Hope and Innovation | Whittier | California | — | — |
| Rocky Mountain Cancer Centers | Denver | Colorado | — | — |
| Florida Cancer Specialists - South | Fort Myers | Florida | — | — |
| Florida Cancer Specialists - North | Tampa | Florida | — | — |
| Illinois Cancer Care | Galesburg | Illinois | — | — |
| Illinois Cancer Specialists | Hinsdale | Illinois | — | — |
| Illinois Cancer Specialists | Niles | Illinois | — | — |
| Fort Wayne Oncology & Hematology | Fort Wayne | Indiana | — | — |
| Horizon Oncology Research, Inc. | Lafayette | Indiana | — | — |
| Center for Cancer and Blood Disorders (CCBD) | Bethesda | Maryland | — | — |
| Hematology-Oncology Associates of Northern NJ, PA | Morristown | New Jersey | — | — |
| New Mexico Cancer Care Alliance | Albuquerque | New Mexico | — | — |
| Clinical Research Alliance | New York | New York | — | — |
| Hudson Valley Hematology Oncology Associates | Poughkeepsie | New York | — | — |
| Willamette Valley Cancer Institute and Research Center | Eugene | Oregon | — | — |
| Tennessee Oncology, PLLC | Chattanooga | Tennessee | — | — |
| St. Joseph Regional Cancer Center | Bryan | Texas | — | — |
| Millennium Oncology | Houston | Texas | — | — |
| Waldron Medical Research and Development Center | Houston | Texas | — | — |
| Cancer Care Centers of South Texas | San Antonio | Texas | — | — |
| Center at Cancer Therapy & Research Center at The University of Texas Health Science Center at San Antonio | San Antonio | Texas | — | — |
| Blood and Cancer Center of East Texas | Tyler | Texas | — | — |
| Shenandoah Oncology, PC | Winchester | Virginia | — | — |
| Northwest Cancer Specialists | Vancouver | Washington | — | — |
| Yakima Valley Memorial Hospital/ North Star Lodge | Yakima | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01677858, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 23, 2022 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01677858 live on ClinicalTrials.gov.