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Completed Phase 2 Interventional Results available

Oral Nitrite in Adults With Metabolic Syndrome and Hypertension

ClinicalTrials.gov ID: NCT01681810

Public ClinicalTrials.gov record NCT01681810. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 11, 2026, 4:52 AM EST

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Official title

An Open-Label Study of Oral Nitrite in Adults With Metabolic Syndrome and Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This research study is being conducted to examine the effects of daily inorganic nitrite treatment on the cardiometabolic and hormonal disturbances observed in overweight/obese adults with the metabolic syndrome and high blood pressure. Ultimately, oral nitrite therapy may have a major impact on the prevention and treatment of both diabetes and cardiovascular disease.

Study identification

NCT ID
NCT01681810
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Gladwin, Mark, MD
Individual
Enrollment
20 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 60 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 2012 (Type not available)
Primary completion
Feb 8, 2018 (Actual)
Completion
Mar 8, 2018 (Actual)
Last update posted
Apr 16, 2019

2012 – 2018

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Montefiore Hospital of University of Pittsburgh Medical Center (UPMC) Pittsburgh Pennsylvania 15213 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01681810, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2019 · Synced Nov 11, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01681810 live on ClinicalTrials.gov.

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