Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Following Total Knee Arthroplasty
Public ClinicalTrials.gov record NCT01683071. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Dose Ranging Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Single Injection Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia in Subjects Undergoing Total Knee Arthroplasty
Study identification
- NCT ID
- NCT01683071
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Enrollment
- 297 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- EXPAREL 67 mg Drug
- EXPAREL 133 mg Drug
- EXPAREL 266 mg Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2012
- Primary completion
- Nov 30, 2013
- Completion
- Nov 30, 2013
- Last update posted
- Dec 8, 2020
2012 – 2013
United States locations
- U.S. sites
- 30
- U.S. states
- 12
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| ACHIEVE CLINICAL RESEARCH LLC 2017 Canyon Road Suite 41 | Birmingham | Alabama | 35216 | — |
| HORIZON RESEARCH GROUP INC 3610 Springhill Memorial Dr. N | Mobile | Alabama | 36608 | — |
| Veritas Research, LLC | Mobile | Alabama | 36660 | — |
| SHOALS MEDICAL TRIALS INC. 1300 S Montgomery Ave | Sheffield | Alabama | 35660 | — |
| PHOENIX ORTHOPAEDIC SURGEONS 2525 W. Greenway Road Suite 114 | Phoenix | Arizona | 85023 | — |
| ALLIANCE RESEARCH CENTERS 24411 Health Center Drive Suite 350 | Laguna Hills | California | 92653 | — |
| ORTHOPADIC SURGERY Loma Linda University Health Care Dept. Pf Orthopaedic Surgery 250 East Caroline Street Suite A | San Bernardino | California | 92508 | — |
| University of California, San Diego | San Diego | California | 92103 | — |
| Ilfeld, Brian (Thornton) UNIVERSITY OF CALIFORNIA, SAN DIEGO 10610 Hunters Glen Drive | San Diego | California | 92130 | — |
| FLORIDA RESEARCH ASSOCIATES, LLC / FLORIDA ORTHOPAEDIC ASSOCIATES 740 W. Plymouth Ave | DeLand | Florida | 32720 | — |
| JACKSON MEMORIAL HOSPITAL UNVERSITY OF MIAMI 1611 Nw. 12th Ave C300 | Miami | Florida | 33136 | — |
| PENSACOLA RESEARCH CONSULTANTS,INC 5149 N.9th Avenue Suite 241 | Pensacola | Florida | 32504 | — |
| SHERIDAN CLINICAL RESEARCH, INC. 1613 N. Harrison Parkway Building C Suite 200 | Sunrise | Florida | 33323 | — |
| PHOENIX CLINICAL RESEARCH,LLC 7171 N. University Drive Suite 100 | Tamarac | Florida | 33321 | — |
| UNIVERSITY OF KANSAS HOSPITAL & MEDICAL CENTER Dept. Of Anesthesiology 3901 Rainbow Blvd. Ms 1034 | Kansas City | Kansas | 66160 | — |
| BEAUMONT HEALTH SYSTEM 44201 Dequindre Road Suite Pob 120 | Troy | Michigan | 48085 | — |
| COOPER UNIVERSITY HOSPITAL 1 Cooper Plaza 202 Dorrance Building | Camden | New Jersey | 08103 | — |
| UNIVERSITY OF MEDICINE AND DENSITRY OF NEW JERSEY/NEW JERSEY MEDICAL SCHOOL 185 South Orange Ave. Department of Anesthesiology - MSB E538 | Newark | New Jersey | 07101 | — |
| NORTHERN WESTCHESTER HOSPTIAL Department Of Clinical Trials 400 East Main St. | Mount Kisco | New York | 10549 | — |
| ST. LUKE-ROOSEVELT HOSPITAL CENTER Dept. Of Anesthesiology 1111 Amsterdam Ave. Travis Bld. 7 | New York | New York | 10025 | — |
| INSALL-SCOTT-KELLY INSTITUTE 210 East 64th Street | New York | New York | 10065 | — |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL Department Of Anesthesiology 101 Manning Drive N0021, Cb 7010 | Chapel Hill | North Carolina | 27599 | — |
| CLEVELAND CLINIC FAIRVIEW HOSPTIAL 1801 Lorain Avenue | Cleveland | Ohio | 44111 | — |
| CLEVELAND CLINIC 9500 Euclid Ave P-77 | Cleveland | Ohio | 44195 | — |
| PENN STATE MILTON S. HERSHEY MEDICAL CENTER H187,500 University Drive | Hershey | Pennsylvania | 17033 | — |
| THOMAS JEFFERSON UNIVERSITY Dept. Of Anesthesiology 111 S. 11th Street Suite G 8490 | Philadelphia | Pennsylvania | 19107 | — |
| UPMC PRESBYTERIAN SHADYSIDE/ DEPT. OF ANESTHESIOLOGY POSNER PAIN CENTER 532 South Aiken Avenue Suite 407 | Pittsburgh | Pennsylvania | 15232 | — |
| UNIVERSITY OF TEXAS MEDICAL BRANCH Dept. Chairman, Orthopedic Surgery & Rehabilitation 2.316 Rebecca Sealy Hospital 301 University Blvd. | Galveston | Texas | 77551 | — |
| RESEARCH CONCEPTS,GP LLC 921 Gessner Rd. Anesthesia Dept., Classroom F | Houston | Texas | 77024 | — |
| CHRISTUS ST. JOHN HOSPITAL 18300 St. John Dr., 2nd Floor, Surgery | Nassau Bay | Texas | 77058 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01683071, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 8, 2020 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01683071 live on ClinicalTrials.gov.