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Completed Phase 2 Interventional Results available

LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung Cancer

ClinicalTrials.gov ID: NCT01685138

Public ClinicalTrials.gov record NCT01685138. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Multicenter, Single-arm Study of Oral LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung Cancer

Study identification

NCT ID
NCT01685138
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
124 participants

Conditions and interventions

Interventions

  • LDK378 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 19, 2012
Primary completion
Jan 21, 2018
Completion
Jan 21, 2018
Last update posted
Mar 25, 2019

2012 – 2018

United States locations

U.S. sites
4
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
Massachusetts General Hospital Mass Gen 5 Boston Massachusetts 02114
Washington University School of Medicine Washington University (16) St Louis Missouri 63110
Sarah Cannon Research Institute Drug Ship - 4 Nashville Tennessee 37203
U of TX Southwestern Medical Center - SimmonsCompCancerCtr Clinical Research Office Dallas Texas 75390

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 47 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01685138, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 25, 2019 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01685138 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →