A Study in Moderate to Severe Rheumatoid Arthritis
Public ClinicalTrials.gov record NCT01710358. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo- and Active-Controlled, Phase 3 Study Evaluating the Efficacy and Safety of Baricitinib in Patients With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether baricitinib is superior to placebo in the treatment of participants with moderately to severely active Rheumatoid Arthritis (RA) who have had an inadequate response to methotrexate (MTX) treatment.
Study identification
- NCT ID
- NCT01710358
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,307 participants
Conditions and interventions
Conditions
Interventions
- Adalimumab Drug
- Baricitinib Drug
- Methotrexate Drug
- Adalimumab Placebo Drug
- Baricitinib Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2012 (Type not available)
- Primary completion
- Mar 2015 (Actual)
- Completion
- Sep 2015 (Actual)
- Last update posted
- Sep 18, 2019
2012 – 2015
United States locations
- U.S. sites
- 45
- U.S. states
- 22
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arthritis & Rheumatology Research | Glendale | Arizona | 85304 | — |
| Sun Valley Arthritis Center, LTD | Peoria | Arizona | 85381 | — |
| Valley Arthritis Care, LLC | Phoenix | Arizona | 85023 | — |
| University of Boards Regent | Tucson | Arizona | 85724 | — |
| Valley Endocrine, Fresno | Fresno | California | 93720 | — |
| Desert Medical Advances | Palm Desert | California | 92260 | — |
| Pacific Arthritis Center | Santa Maria | California | 93454 | — |
| Inlande Rheumatology Clinical Trials | Upland | California | 91786 | — |
| Boulder Medical Center | Boulder | Colorado | 80304 | — |
| Clinical Research Center of CT/NY | Danbury | Connecticut | 06810 | — |
| New England Research Associates | Trumbull | Connecticut | 06611 | — |
| Delaware Arthritis | Lewes | Delaware | 19958 | — |
| Orthopedic Research Institute | Boynton Beach | Florida | 33472 | — |
| Jeffrey Alper, M.D. | Naples | Florida | 34102 | — |
| Sun Coast Clinical Research, Inc | New Port Richey | Florida | 34652 | — |
| Rheumatology Associates of Central Florida | Orlando | Florida | 32806 | — |
| Integral Rheumatology & Immunology Specialists | Plantation | Florida | 33324 | — |
| McIlwain Medical Group | Tampa | Florida | 33613 | — |
| Indiana University Health | Indianapolis | Indiana | 46202 | — |
| Diagnostic Rheumatology and Research | Indianapolis | Indiana | 46227 | — |
| Goldpoint Clinical Research LLC | Indianapolis | Indiana | 46260 | — |
| West Michigan Rheumatology | Grand Rapids | Michigan | 49546 | — |
| University of Missouri | Columbia | Missouri | 65212 | — |
| Dr. George Timothy Kelly | Las Vegas | Nevada | 89128 | — |
| (AOA) Arthritis & Osteoporosis Associates | Freehold | New Jersey | 07728 | — |
| Bio Behavioral Health | Toms River | New Jersey | 08755 | — |
| Drug Trials of America | Hartsdale | New York | 10530 | — |
| Asheville Rheumatology & Osteoporosis Research Assoc, PA | Asheville | North Carolina | 28803 | — |
| Paramount Medical Research | Middleburg Heights | Ohio | 44130 | — |
| Health Research Institute | Oklahoma City | Oklahoma | 73103 | — |
| Healthcare Research Consultant | Tulsa | Oklahoma | 74135 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| East Penn Rheumatology | Bethlehem | Pennsylvania | 18017 | — |
| Clinical Research Center of Reading, LLP | Wyomissing | Pennsylvania | 19610 | — |
| Carolina Rheumatology and Neurology Associates | Myrtle Beach | South Carolina | 29572 | — |
| Metroplex Clinical Research Center | Dallas | Texas | 75231 | — |
| Pioneer Research Solutions | Houston | Texas | 77008 | — |
| Accurate Clinical Research | Houston | Texas | 77084 | — |
| Arthritis & Osteoporosis Associates LLP | Lubbock | Texas | 79424 | — |
| Accurate Clinical Research | Nassau Bay | Texas | 77058 | — |
| Accurate Clinical Research | Webster | Texas | 77508 | — |
| Center for Arthritis and Rheumatic Diseases, PC | Chesapeake | Virginia | 23320 | — |
| The Seattle Arthritis Clinic | Seattle | Washington | 98133 | — |
| Vancouver Clinic | Vancouver | Washington | 98664 | — |
| Rheumatology and Immunotherapy Center | Franklin | Wisconsin | 53132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 168 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01710358, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 18, 2019 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01710358 live on ClinicalTrials.gov.