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Completed Phase 3 Interventional

Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

ClinicalTrials.gov ID: NCT01714661

Public ClinicalTrials.gov record NCT01714661. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Parallel, 26-Week, Phase 3 Study of 2 Doses of an Alpha-7 Nicotinic Acetylcholine Receptor Agonist (EVP-6124) or Placebo as an Adjunctive Pro-cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine if EVP-6124 (an alpha-7 nAChR agonist) enhances the cognitive abilities of subjects with Schizophrenia who are also taking stable antipsychotic therapy.

Study identification

NCT ID
NCT01714661
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
FORUM Pharmaceuticals Inc
Industry
Enrollment
753 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 50 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 2012 (Type not available)
Primary completion
Dec 2015 (Actual)
Completion
Dec 2015 (Actual)
Last update posted
May 3, 2016

2012 – 2015

United States locations

U.S. sites
38
U.S. states
19
U.S. cities
38
Facility City State ZIP Site status
Not listed Tucson Arizona — —
Not listed Anaheim California — —
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Not listed Oceanside California — —
Not listed Orange California — —
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Not listed Torrance California — —
Not listed Lauderhill Florida — —
Not listed Miami Florida — —
Not listed North Miami Florida — —
Not listed Orange City Florida — —
Not listed Atlanta Georgia — —
Not listed Chicago Illinois — —
Not listed Wichita Kansas — —
Not listed Shreveport Louisiana — —
Not listed Minneapolis Minnesota — —
Not listed Flowood Mississippi — —
Not listed Creve Coeur Missouri — —
Not listed O'Fallon Missouri — —
Not listed St Louis Missouri — —
Not listed Omaha Nebraska — —
Not listed Marlton New Jersey — —
Not listed Albuquerque New Mexico — —
Not listed Cedarhurst New York — —
Not listed New York New York — —
Not listed Charlotte North Carolina — —
Not listed Durham North Carolina — —
Not listed Cleveland Ohio — —
Not listed Oklahoma City Oklahoma — —
Not listed Conshohocken Pennsylvania — —
Not listed Norristown Pennsylvania — —
Not listed Philadelphia Pennsylvania — —
Not listed Dallas Texas — —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 56 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01714661, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 3, 2016 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT01714661 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →