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Completed Phase 3 Interventional

Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

ClinicalTrials.gov ID: NCT01714661

Public ClinicalTrials.gov record NCT01714661. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 4:39 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled, Parallel, 26-Week, Phase 3 Study of 2 Doses of an Alpha-7 Nicotinic Acetylcholine Receptor Agonist (EVP-6124) or Placebo as an Adjunctive Pro-cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine if EVP-6124 (an alpha-7 nAChR agonist) enhances the cognitive abilities of subjects with Schizophrenia who are also taking stable antipsychotic therapy.

Study identification

NCT ID
NCT01714661
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
FORUM Pharmaceuticals Inc
Industry
Enrollment
753 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 50 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2012
Primary completion
Nov 30, 2015
Completion
Nov 30, 2015
Last update posted
May 2, 2016

2012 – 2015

United States locations

U.S. sites
38
U.S. states
19
U.S. cities
38
Facility City State ZIP Site status
Not listed Tucson Arizona
Not listed Anaheim California
Not listed Bellflower California
Not listed Costa Mesa California
Not listed Culver City California
Not listed Downey California
Not listed Escondido California
Not listed Los Angeles California
Not listed Oceanside California
Not listed Orange California
Not listed San Diego California
Not listed Torrance California
Not listed Lauderhill Florida
Not listed Miami Florida
Not listed North Miami Florida
Not listed Orange City Florida
Not listed Atlanta Georgia
Not listed Chicago Illinois
Not listed Wichita Kansas
Not listed Shreveport Louisiana
Not listed Minneapolis Minnesota
Not listed Flowood Mississippi
Not listed Creve Coeur Missouri
Not listed O'Fallon Missouri
Not listed St Louis Missouri
Not listed Omaha Nebraska
Not listed Marlton New Jersey
Not listed Albuquerque New Mexico
Not listed Cedarhurst New York
Not listed New York New York
Not listed Charlotte North Carolina
Not listed Durham North Carolina
Not listed Cleveland Ohio
Not listed Oklahoma City Oklahoma
Not listed Conshohocken Pennsylvania
Not listed Norristown Pennsylvania
Not listed Philadelphia Pennsylvania
Not listed Dallas Texas

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 56 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01714661, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 2, 2016 · Synced Sep 6, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01714661 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →