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Completed Phase 3 Interventional Results available

SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

ClinicalTrials.gov ID: NCT01718483

Public ClinicalTrials.gov record NCT01718483. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The SPD489-343, Phase 3, Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled, Dose-optimization Study to Evaluate the Efficacy, Safety, and Tolerability of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of the study is to demonstrate the efficacy of SPD489 compared with placebo in adults (18 55 years of age inclusive) with moderate to severe Binge Eating Disorder at Visit 8 (Weeks 11 and 12) as measured by the number of binge days (defined as days during which at least 1 binge episode occurs) per week as assessed by clinical interview based on subject diary

Study identification

NCT ID
NCT01718483
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Shire
Industry
Enrollment
383 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 25, 2012
Primary completion
Sep 24, 2013
Completion
Sep 24, 2013
Last update posted
Jun 7, 2021

2012 – 2013

United States locations

U.S. sites
43
U.S. states
25
U.S. cities
43
Facility City State ZIP Site status
Birmingham Research Group Birmingham Alabama 35216
Clinical Study Centers, LLC Little Rock Arkansas 72211
Trimed Clinical Trials Corona California 92880
Pharmacology Research Institute Encino California 91316
Pharmacology Research Institute Los Alamitos California 90720
Pacific Research Partners, LLC Oakland California 94812
Research Across America Santa Ana California 92705
Western Affiliated Research Institute, Inc. Denver Colorado 80209
Gulfcoast Clinical Research Fort Myers Florida 33912
Clinical Neuroscience Solutions, Inc. Jacksonville Florida 32256
Fidelity Clinical Research, Inc. Lauderhill Florida 33319
Compass Research LLC Leesburg Florida 34748
Scientific Clinical Research Inc. North Miami Florida 33161
Uptown Research Institute Chicago Illinois 60640
Alexian Brothers Behavioral Health Hospital Hoffman Estates Illinois 60169
AMR Baber Research, Inc. Naperville Illinois 60563
Goldpoint Clinical Research, LLC Indianapolis Indiana 46260
Cypress Medical Research Center, LLC Wichita Kansas 67226
McLean Hospital Belmont Massachusetts 02478
St. Charles Psychiatric Associates/Midwest Research Group Saint Charles Missouri 63304
Center for Psychiatry and Behavioral Medicine, Inc. Las Vegas Nevada 89128
Pacific Research for Research and Evaluation Albuquerque New Mexico 87102
Wake Research Associates, LLC Raleigh North Carolina 27612
Community Research Cincinnati Ohio 45227
Midwest Clinical Research Center, LLC Dayton Ohio 45417
North Star Medical Research Middleburg Heights Ohio 44130
IPS Research Company Oklahoma City Oklahoma 73103
Oregon Center for Clinical Investigations, Inc. Salem Oregon 97301
The Clinical Trials Center, LLC Jenkintown Pennsylvania 19046
Suburban Research Associates Media Pennsylvania 19063
Clinical Trials Research Services, LLC Pittsburgh Pennsylvania 15206
Radiant Research, Inc. Anderson South Carolina 29621
Coastal Carolina Research Center Mt. Pleasant South Carolina 29464
Clinical Neuroscience Solutions, Inc. Memphis Tennessee 38119
Future Search Trials Austin Texas 78731
Futuresearch Trials of Dallas, L.P. Dallas Texas 75231
Grayline Clinical Drug Trials Wichita Falls Texas 76309
Radiant Research, Inc. Murray Utah 84123
Neuropsychiatric Associates, LLC Woodstock Vermont 05091
Charlottesville Medical Research Center, LLC Charlottesville Virginia 22911
Alliance Research Group Richmond Virginia 23230
Northwest Clinical Research Center Bellevue Washington 98007
Dean Foundation for Health, Research and Educations, Inc. Middleton Wisconsin 53562

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01718483, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 7, 2021 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01718483 live on ClinicalTrials.gov.

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