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Completed Phase 4 Interventional Results available

Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection)

ClinicalTrials.gov ID: NCT01722045

Public ClinicalTrials.gov record NCT01722045. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 1:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label Study of the Efficacy, Safety, and Tolerability of Intravitreal Administration of VEGF Trap-Eye (Intravitreal Aflibercept Injection) in Patients With Neovascular Age-Related Macular Degeneration

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a phase 4, open-label, single arm, multicenter, clinical study in patients with neovascular AMD designed to evaluate the efficacy and safety of Intravitreal Aflibercept Injection (IAI) administered over 2 years , and to provide clinical information from the first year in the trial evaluating the adverse effects, if any, on the corneal endothelium following administration of IAI.

Study identification

NCT ID
NCT01722045
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Regeneron Pharmaceuticals
Industry
Enrollment
154 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2012
Primary completion
Aug 31, 2015
Completion
Aug 31, 2015
Last update posted
Dec 21, 2017

2012 – 2015

United States locations

U.S. sites
49
U.S. states
25
U.S. cities
49
Facility City State ZIP Site status
Not listed Phoenix Arizona
Not listed Tucson Arizona
Not listed Beverly Hills California
Not listed Oakland California
Not listed Palm Desert California
Not listed Sacramento California
Not listed Santa Ana California
Not listed Westlake Village California
Not listed Colorado Springs Colorado
Not listed Golden Colorado
Not listed Boynton Beach Florida
Not listed Fort Lauderdale Florida
Not listed Fort Myers Florida
Not listed Pensacola Florida
Not listed Plantation Florida
Not listed Tampa Florida
Not listed Winter Haven Florida
Not listed Augusta Georgia
Not listed Oak Park Illinois
Not listed New Albany Indiana
Not listed Wichita Kansas
Not listed Lexington Kentucky
Not listed Boston Massachusetts
Not listed Worcester Massachusetts
Not listed Jackson Michigan
Not listed Lincoln Nebraska
Not listed Las Vegas Nevada
Not listed Portsmouth New Hampshire
Not listed Bloomfield New Jersey
Not listed Lawrenceville New Jersey
Not listed Northfield New Jersey
Not listed Teaneck New Jersey
Not listed Rochester New York
Not listed Asheville North Carolina
Not listed Oklahoma City Oklahoma
Not listed Portland Oregon
Not listed Salem Oregon
Not listed Kingston Pennsylvania
Not listed Pittsburgh Pennsylvania
Not listed Florence South Carolina
Not listed Ladson South Carolina
Not listed West Columbia South Carolina
Not listed Rapid City South Dakota
Not listed Nashville Tennessee
Not listed Arlington Texas
Not listed Fort Worth Texas
Not listed Houston Texas
Not listed San Antonio Texas
Not listed Seattle Washington

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01722045, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 21, 2017 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01722045 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →