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Completed Phase 1 Interventional

A Study to Determine the Relative Bioavailability of the MEK Inhibitor, Trametinib, in Subjects With Solid Tumor Malignancies

ClinicalTrials.gov ID: NCT01725100

Public ClinicalTrials.gov record NCT01725100. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Randomized, 2-treatment, 2-period, 2-way Crossover, Single-dose Study to Determine the Relative Bioavailability of the MEK Inhibitor, Trametinib, in Subjects With Solid Tumor Malignancies

Study identification

NCT ID
NCT01725100
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
80 participants

Conditions and interventions

Conditions

Interventions

  • GSK1120212B (Lower DMSO content) Drug
  • GSK1120212B (Standard DMSO content) Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 4, 2013
Primary completion
Jan 29, 2015
Completion
Jan 29, 2015
Last update posted
Nov 12, 2017

2013 – 2015

United States locations

U.S. sites
4
U.S. states
3
U.S. cities
4
Facility City State ZIP Site status
GSK Investigational Site Goodyear Arizona 85338
GSK Investigational Site Scottsdale Arizona 85259
GSK Investigational Site Sarasota Florida 34232
GSK Investigational Site Nashville Tennessee 37203

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01725100, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 12, 2017 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01725100 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →